Patents by Inventor Shelly MAMAN

Shelly MAMAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of cancer and inhibition of metastasis using hemoglobin beta subunit
    Patent number: 10561712
    Abstract: The beta 2 subunit of mouse hemoglobin (HBB2) has been identified as soluble factor from mouse lungs that exhibits cytostatic/cytotoxic activity against neuroblastoma lung micrometastases. The beta subunit of human hemoglobin (HBB) has been found to have similar activity. Methods of using these proteins and fragments thereof in the treatment of cancer and inhibition of metastasis are provided, along with methods of screening a subject for micrometastases by detecting HBB in a biological sample.
    Type: Grant
    Filed: May 21, 2015
    Date of Patent: February 18, 2020
    Assignees: UNIVERSITY OF MARYLAND, BALTIMORE, RAMOT AT TEL AVIV UNIVERSITY LTD.
    Inventors: Wuyuan Lu, Issac Witz, Shelly Maman
  • TREATMENT OF CANCER AND INHIBITION OF METASTASIS USING HEMOGLOBIN BETA SUBUNIT
    Publication number: 20170304410
    Abstract: The beta 2 subunit of mouse hemoglobin (HBB2) has been identified as soluble factor from mouse lungs that exhibits cytostatic/cytotoxic activity against neuroblastoma lung micrometastases. The beta subunit of human hemoglobin (HBB) has been found to have similar activity. Methods of using these proteins and fragments thereof in the treatment of cancer and inhibition of metastasis are provided, along with methods of screening a subject for micrometastases by detecting HBB in a biological sample.
    Type: Application
    Filed: May 21, 2015
    Publication date: October 26, 2017
    Applicants: UNIVERSITY OF MARYLAND, BALTIMORE, RAMOT AT TEL-AVIV UNIVERSITY LTD.
    Inventors: Wuyuan LU, Issac WITZ, Shelly MAMAN