Abstract: Semiconductor devices and methods of manufacture which utilize lids in order to constrain thermal expansion during annealing are presented. In some embodiments lids are placed and attached on encapsulant and, in some embodiments, over first semiconductor dies. As such, when heat is applied, and the encapsulant attempts to expand, the lid will work to constrain the expansion, reducing the amount of stress that would otherwise accumulate within the encapsulant.

Abstract: A semiconductor memory device includes a substrate having a conductor region thereon, an interlayer dielectric layer on the substrate, and a conductive via electrically connected to the conductor region. The conductive via has a lower portion embedded in the interlayer dielectric layer and an upper portion protruding from a top surface of the interlayer dielectric layer. The upper portion has a rounded top surface. A storage structure conformally covers the rounded top surface.

Abstract: Provided is a system and platform for Machine Learning (ML) based Data Discovery and Classification. The system and platform comprising components of a user console, a ML agent, and a ML data engine. By way of a ML pipeline, sensitive data is obfuscated that would otherwise by in the clear when transmitted to a centralized server. The ML model pipeline decouples embedding from model training. In a first step, the ML Agent runs on data endpoint machine or proxy to convert clear text data to embedding vectors. In a second step, the ML data engine runs on a centralized server to train models using the embedding vectors. The separation of pipeline components and respective handling of workflow requests and messages associated therewith prevents the transfer of clear data in the open. Other embodiments disclosed.

Abstract: An atomization device and a method of predicting atomization time for the same are provided. The atomization device includes a control module, an atomization module and a breathing sensing module. The method includes: configuring the breath sensing module to detect inhalations of a user using the atomization device, so as to generate initial breath data correspondingly; and configuring the control module to perform: comparing inhalation data of the initial breath data with a valid inhalation standard to obtain valid inhalation data and filter noise; statistically analyzing the valid inhalation data to generate a predicted value of inhalation time; calculating an atomization time according to the predicted value of the inhalation time; and generating a driving signal to drive the atomization module to perform atomization according to the atomization time.

Abstract: A method includes receiving an input for a large language model (LLM) from a user. The method also includes generating one or more token embeddings based on the input. The method further includes generating one or more prompt embeddings based on the input using a contextual prompt generator (CPG), the one or more prompt embeddings representing new or updated information that is not contained in existing knowledge of the LLM. The method also includes providing the one or more token embeddings and the one or more prompt embeddings to the LLM. In addition, the method includes outputting a prediction based on the one or more token embeddings and the one or more prompt embeddings using the LLM, wherein the prediction reflects the new or updated information represented by the one or more prompt embeddings.

Abstract: An integrated circuit (IC) device includes a substrate and a circuit region over the substrate. The circuit region includes at least one active region extending along a first direction, at least one gate region extending across the at least one active region and along a second direction transverse to the first direction, and at least one first input/output (IO) pattern configured to electrically couple the circuit region to external circuitry outside the circuit region. The at least one first IO pattern extends along a third direction oblique to both the first direction and the second direction.

Abstract: A semiconductor package is provided, which includes a first chip disposed over a first package substrate, a molding compound surrounding the first chip, a first thermal interface material disposed over the first chip and the molding compound, a heat spreader disposed over the thermal interface material, and a second thermal interface material disposed over the heat spreader. The first thermal interface material and the second thermal interface material have an identical width.

Abstract: A package structure is provided. The package structure includes a first conductive pad in a first insulating layer, a conductive via in a second insulating layer directly under the first conductive pad, and a first under bump metallurgy structure directly under the first conductive via. In a first horizontal direction, the conductive via is narrower than the first under bump metallurgy structure, and the first under bump metallurgy structure is narrower than the first conductive pad.

Abstract: A semiconductor die package is provided. The semiconductor die package includes a semiconductor die and a package substrate supporting and electrically connected to the semiconductor die. The semiconductor die has a corner. The package substrate includes several conductive lines, and one of the conductive lines under the corner of the semiconductor die includes a first line segment and a second line segment connected to the first line segment. The first line segment is linear and extends in a first direction. The second line segment is non-linear and has a varying extension direction.

Abstract: The present disclosure provides a novel method for modulating mucosal immune response, comprising administering an antigen to a mucosal site of a subject in need thereof, and administering an immunomodulator to a different anatomical mucosal site of said subject. The antigen may be administered to sublingual mucosa and the immunomodulator may be administered to intranasal mucosa. An immune response involving production of IgG and IgA against the antigen may be elicited.

Abstract: The present disclosure provides a method for the treatment or prophylaxis of coronavirus infection, comprising administering a therapeutically effective amount of an immunomodulator to a subject in need thereof or at risk of coronavirus infection. A vaccine composition comprising a pharmaceutically effective amount of an immunomodulator is also provided.

Abstract: An earphone has a housing, a sound output hole, a first touch sensor, a second touch, a third touch sensor, and a microprocessor. The microprocessor is coupled to the first touch sensor, the second touch sensor and the third touch sensor for determining whether the earphone is worn on an ear according to the sensing result of the first touch sensor, determining whether the earphone is held in hand according to the sensing result of the second touch sensor, and providing a corresponding control function according to the sensing result of the third touch sensor.

Abstract: The disclosure provides an electronic device, including a body and a mouse body. The body includes an accommodating area. The mouse body includes a touch surface and is detachably disposed in the accommodating area.

Abstract: A touch detection apparatus and a touch detection method are provided. The touch detection apparatus includes a sensing element and a detection circuit. The touch detection method includes the following steps. At least one touch sensing value is provided by the sensing element. Whether a first object touches the sensing element is determined by the detection circuit according to the at least one touch sensing value and a first reference value in a first stage. If the first object touches the sensing element, a second reference value is calculated by the detection circuit according to the at least one touch sensing value and the detection circuit enters a second stage. Whether a second object touches the first object is determined by the detection circuit according to the at least one touch sensing value and the second reference value in the second stage.

Abstract: The present invention relates to a fluorescent polymer cast on the surface of wells of a plate and a plate comprising the fluorescent polymer. The plate is used in a method for calibrating read-out values of plate readers. The method for calibrating the plate readers can effectively reduce the deviation of read-out values among different plate readers.

Abstract: An earphone has a housing, a sound output hole, a first touch sensor, a second touch, a third touch sensor, and a microprocessor. The microprocessor is coupled to the first touch sensor, the second touch sensor and the third touch sensor for determining whether the earphone is worn on an ear according to the sensing result of the first touch sensor, determining whether the earphone is held in hand according to the sensing result of the second touch sensor, and providing a corresponding control function according to the sensing result of the third touch sensor.

Abstract: A touch detection apparatus and a touch detection method are provided. The touch detection apparatus includes a sensing element and a detection circuit. The touch detection method includes the following steps. At least one touch sensing value is provided by the sensing element. Whether a first object touches the sensing element is determined by the detection circuit according to the at least one touch sensing value and a first reference value in a first stage. If the first object touches the sensing element, a second reference value is calculated by the detection circuit according to the at least one touch sensing value and the detection circuit enters a second stage. Whether a second object touches the first object is determined by the detection circuit according to the at least one touch sensing value and the second reference value in the second stage.

Abstract: A detoxified recombinant E. coli heat-labile enterotoxin mutant, LTS61K, is employed as a carrier protein to conjugate polysaccharide. The LTS61K contains a mutated mature sub-unit A (LTA) that includes lysine at amino acid position 61 and a wild-type mature sub-unit B (LTB). Various types of bacterial capsular polysaccharide antigens were chemically conjugated with the LTS61K protein by a reductive amination reaction. The conjugated polysaccharide-LTS61K products were physically, chemically and biochemically identified as soluble form. Rabbits were immunized intramuscularly to determine the immunogenicity of conjugated vaccines by ELISA to detect anti-polysaccharide antigen IgG titers and serum bactericidal assay thereby determining the functional activity of the antibodies. Study results show that conjugated polysaccharide-LTS61K vaccines induce higher polysaccharide-specific IgG titers and greater bactericidal activity in sera than that of polysaccharide alone or polysaccharide mixed with LTS61K.