Abstract: CRISPR/CAS-related compositions and methods for treatment of Leber's Congenital Amaurosis 10 (LCA10) are disclosed.

Abstract: The present invention provides AAV capsid proteins comprising a modification in the amino acid sequence and virus capsids and virus vectors comprising the modified AAV capsid protein. The invention also provides methods of administering the virus vectors and virus capsids of the invention to a cell or to a subject in vivo.

Abstract: The present invention relates to a method and system for vehicle data integration. The method is comprised of the steps of: capturing a plurality of vehicle data and sending the vehicle data to a data filter; configuring the data filter to determine the quality of the vehicle data; reading a plurality of contents of different properties of the vehicle data and sending the contents to a server; configuring the sever to determine if at least two contents of different properties exist within a predetermined time interval; matching the contents into at least one dataset and sending the dataset to a buffer; configuring the buffer to determine if any of the datasets in the buffer has occurred for over a predetermined number of times; and sending at least one dataset having occurred for over the predetermined number of times to a database.

Abstract: CRISPR/CAS-related compositions and methods for treatment of Leber's Congenital Amaurosis 10 (LCA10) are disclosed.

Abstract: Webpages configured for display on a full-sized screen such as a computer monitor (111) are reconfigured for use with a mobile device in accordance with a user's preferences. A custom rendering tool engages the user in customizing the webpage in order to render the webpage information suitable for display on a mobile device. A browser toolbar is used, by which the user may highlight a section of interest section (121) from a webpage and save the customization information. A proxy server receives the customization information and uses the information to accurately retrieve the sections of interest later, even after the webpage or the section has been updated.

Abstract: Integrated circuits with dynamic pin routing capabilities are provided. An integrated circuit may include circuitry under test and a dynamic signal routing controller. The dynamic signal routing controller may include multiplexers, a test register, and a signal select register. The circuitry under test may be connected to internal test lines that receive static test signals and dynamic test signals. The internal test lines that receive static test signals may be selectively routed to the test register (e.g., test registers store static test signals) while the internal test lines that receive dynamic test signals may be selectively routed to test pins (e.g., dynamic test signals are driven through the test pins). Each multiplexer may have a given input that is connected to the test register and additional inputs that are connected to the test pins. The signal select register stores control bits that configure the routing performed by each multiplexer.

Abstract: Webpages configured for display on a full-sized screen such as a computer monitor (111) are reconfigured for use with a mobile device in accordance with a user's preferences. A custom rendering tool engages the user in customizing the webpage in order to render the webpage information suitable for display on a mobile device. A browser toolbar is used, by which the user may highlight a section of interest section (121) from a webpage and save the customization information. A proxy server receives the customization information and uses the information to accurately retrieve the sections of interest later, even after the webpage or the section has been updated.

Abstract: The present invention provides a fuel cell device, which at least comprises: at least one membrane electrode assembly, at least one fuel flow board, and at least one permeability membrane; wherein, the membrane electrode assembly is provided with an anode electrode, a cathode electrode, and an electrolyte membrane; and, the permeability membrane is configured between the membrane electrode assembly and the fuel flow board, so that the liquid fuel flowing into the fuel flow board could permeate into the permeability membrane, and reducing the density of liquid fuel permeating from the permeability membrane; and, the liquid fuel permeating from the permeability membrane is the liquid fuel with lower density, and is supplied to the anode electrode of the membrane electrode assembly for electrochemical reaction.

Abstract: An organic electroluminescent material of the formula: wherein R1, R2 and R3 are selected from the group consisting of hydrogen, halogen, nitryl, alkyl, cycloalkyl, alkyloxy, alkenyl, amine, aryl, polyaryl, arylalkyl, and propenyloxy, Ar3 is at least one selected from the group consisting of aryl and polyaryl and A and B are at least one selected from the group consisting of hydrogen, alkyl, cycloalkyl, alkyloxy, alkenyl, amine, aryl, polyaryl, arylalkyl, and propenyloxy. An electroluminescent device having the organic electroluminescent material is provided.

Abstract: An organic electroluminescent material of the formula: wherein M is at least one selected from the group consisting of —CH2—, —CH2CH2—, —CH2CH2CH2—, —CH2C(CH3)2CH2—, and —CH2YCH2—, X is at least one selected from the group consisting of oxygen, sulfur, nitrogen, carbon, alkyl, silicon, silyl, phosphorus, aryl, and polyaryl, and n is depending on the amount of free radicals of X. Y is at least one selected from the group consisting of oxygen, sulfur, nitrogen and SiR1R2. Wherein, R1 and R2 is at least one selected from the group consisting of substituted or unsubstituted alkyl having 1 to 10 carbon atoms, and substituted or unsubstituted aryl having 6 to 30 carbon atoms. This invention also discloses an organic electroluminescent element having the organic electroluminescent material.

Abstract: The present invention relates to an organic electroluminescent device, comprising a first electrode, an organic luminescent layer and a second electrode which disposed over a substrate. The organic electroluminescent layer comprises compound of formula (I) compound, wherein that Ar1—Ar6 are individual hydrogen, substituted or unsubstituted C1-6 alkyl, substituted or unsubstituted C3-6 cycloalkyl, substituted or unsubstituted C3-10 alkenyl, substituted or unsubstituted C6-40 aromatic amino, substituted or unsubstituted C6-40 aromatic, substituted or unsubstituted C6-40 poly cyclic aromatic, or substituted or unsubstituted C6-40 aralkyl.

Abstract: An organic electroluminescent material of the formula: 1

Abstract: An organic electroluminescent material of the formula: 1

Abstract: A method for forming a drying film of an organic electroluminescent device includes the steps of: providing a desiccant, and depositing the desiccant to form the drying film. The drying film is formed on a lid of the organic electroluminescent device or over a substrate thereof. Furthermore, an organic electroluminescent device is also disclosed. The organic electroluminescent device includes a substrate, a first electrode, an organic functional layer, a second electrode, a lid or passivation film, and a drying film. The substrate and the lid or passivation layer form an airtight space, in which the first electrode, organic functional layer and second electrode are located. In such cases, the drying film is formed with a deposition method.

Abstract: A foldable transformer includes an enclosure (10), a plug assembly (12), and a locating assembly (14). The enclosure has a storage cavity (16) at a top end thereof. A window (20) is defined in the enclosure in communication with a bottom portion of the storage cavity, for receiving the plug assembly therethrough. The plug assembly includes a pair of inserting pins (34), a rotatable rod (36) having an arched profile, a pair of metal ears (38), and a pair spring pins (44). Each inserting pin is made of conductive material, is insert-molded in the rod, and electrically connects with a corresponding ear. The locating assembly includes a pair of slots (48) for receiving the spring pins, and a cam (56) for resiliently engaging with the plug assembly so that the plug assembly can be disengagably fixed in a folded position or an unfolded position.