Abstract: A method for managing storage performance consistency, where the method determines a target throughput for writes to a memory sub-system, increases a tracking variable with a granularity based on the target throughput at fixed intervals, decreases the tracking variable based on writes of host data received from a host system to the memory sub-system, and adjusts a priority of host data writes to the memory sub-system relative to writes of reclaimed data from the memory sub-system in response to the tracking variable indicating a deviation from the target throughput.

Abstract: Disclosed are a method, apparatus, device and system for processing commodity transaction, and a storage medium. The method includes: acquiring a commodity order of a user from an E-commerce platform; generating a manufacturing order according to the commodity order, and providing the manufacturing order to a manufacturer to enable the manufacturer to produce a commodity on the basis of the manufacturing order; and providing a production progress and/or a delivery progress of the commodity to a user.

Abstract: Disclosed are a commodity customization method, apparatus and device, and a storage medium. The method includes: receiving a commodity creating request of a first user and providing a created commodity editing interface; creating a target customizable commodity according to basic information and customizable component information configured by the first user; and sending relevant information about the target customizable commodity to an E-commerce platform server for publishment.

Abstract: Systems and methods are provided for retraining a machine learning model to learn a retrained machine learning model. After a computing system receives an execution log of a prediction service and an observed user action, it may create retraining data. From the retraining data, the computing system may learn a retrained machine learning model. The retrained machine learning model can be used to compute future predictions of user actions if it has an improved performance over the original machine learning model.

Abstract: An entry is read from a first memory component, the entry associated with a first logical address. The first entry includes a first physical address to a segment of a logical-to-physical address map in a second memory component and an indication of whether the segment of the logical-to-physical address map is stored in the first memory component. The segment of the logical-to-physical address map includes a second entry associated with the first logical address. A second physical address is written to the second entry in the first memory component based on a determination from the indication that the segment of the logical-to-physical address map is stored in the first memory component.

Abstract: A method for managing storage performance consistency, where the method determines a target throughput for writes to a memory sub-system, increases a tracking variable with a granularity based on the target throughput at fixed intervals, decreases the tracking variable based on writes of host data received from a host system to the memory sub-system, and adjusts a priority of host data writes to the memory sub-system relative to writes of reclaimed data from the memory sub-system in response to the tracking variable indicating a deviation from the target throughput.

Abstract: Techniques are provided for presenting and dynamically updating a user interface that represents features/services associated with a service provider. For example, a user interface element associated with services offered by a service provider may be maintained. Further, instructions to present the user interface element with at least a first portion that represents a service of the services that is accessible may be provided. Information corresponding to an interaction with the service provider may be received. A second portion of the user interface element to present may be determined based at least in part on the received information and aggregate user data that identifies interactions by a plurality of users with the services offered by the service provider. Instructions may be provided to present the user interface element with the first portion and the determined second portion.

Abstract: Disclosed are various embodiments for an automated service agent. Natural language inputs are obtained from a client. The natural language inputs and other data are input to machine learning models to identify intents reflected in the natural language inputs. A state in a workflow is updated to reflect the identified intents. Responses may be communicated to the client to further progress in the workflow.

Abstract: A novel nucleoside phosphoramidate compound of the formula below, or a stereoisomer, salt, hydrate, solvate or crystal thereof for the treatment of Flaviviridae family viral infection, especially hepatitis C viral infection, and having a good anti-HCV effect; a pharmaceutical composition having the compound, or a stereoisomer, salt, hydrate, solvate or crystal thereof:

Abstract: In the field of pharmaceutical chemistry compounds of general formula I having heteroaryl alkynyl moiety or pharmaceutically acceptable salts, isomers, solvates, crystals or prodrugs thereof, and pharmaceutical compositions including these compounds, as well as uses of these compounds and compositions thereof in the manufacture of a medicament. The compounds have a strong inhibitory effect on BCR-ABL tyrosine kinase and are useful for treating diseases, such as tumors.

Abstract: A novel nucleoside phosphoramidate compound, or a stereoisomer, salt, hydrate, solvate or crystal thereof for the treatment of Flaviviridae family viral infection, especially hepatitis C viral infection is provided. The pharmaceutical composition having the compound, or a stereoisomer, salt, hydrate, solvate or crystal thereof and a use of the compound or the composition in the treatment of Flaviviridae family viral infection, especially hepatitis C viral infection. The compound has a good anti-HCV effect.

Abstract: Disclosed are 3-aryl-6-aryl-[1,2,4]triazolo[4,3-a]pyridines thereof, represented by the Formula (I) wherein Ar1, Ar2, R1-R3 are defined herein. Compounds having Formula (I) are inhibitors of cell proliferation. Therefore, compounds of the invention may be used to treat clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.

Abstract: In the field of pharmaceutical chemistry compounds of general formula I having heteroaryl alkynyl moiety or pharmaceutically acceptable salts, isomers, solvates, crystals or prodrugs thereof, and pharmaceutical compositions including these compounds, as well as uses of these compounds and compositions thereof in the manufacture of a medicament. The compounds have a strong inhibitory effect on BCR-ABL tyrosine kinase and are useful for treating diseases, such as tumors.

Abstract: The present invention belongs to the field of pharmaceutical chemistry, and specifically relates to compounds having an alkynyl heteroaromatic ring structure and pharmaceutically acceptable salts, stereoisomers, N-oxides, solvates, or prodrugs thereof, and pharmaceutical compositions comprising these compounds, as well as uses of these compounds and compositions in the manufacture of a medicament. The compounds of the present invention and the pharmaceutically acceptable salts, stereoisomers, N-oxides, solvates or prodrugs thereof and the pharmaceutical compositions comprising the compounds have better anti-tumor activity.

Abstract: A method of object customization by high-speed and realistic 3D rendering through web pages, including generating a 3D model of an object with a three dimensional modeling tool; outputting the 3D model to a 3D model file; loading the 3D model file into the system 400; preprocessing the 3D model file; and generating a binary snapshot file of the 3D model file. The method further includes loading the binary snapshot file; color-separated rendering of various parts of the 3D model of the object; and saving the data of the color-separated rendering in mask images. The method additionally includes calculating object portion specifications and object portion extensibility based on user selection of targeted areas of the 3D model image; displaying the subsequent targeted portions of the 3D model after recalculation; and displaying the resulting images of the 3D model of the object after combining the calculated portions with the 3D model, without rerendering the 3D model.

Abstract: The present invention relates to the field of obesity. More specifically, the present invention provides methods and compositions useful in treating obesity and obesity-associated conditions. In a specific embodiment, a method for treating obesity comprises administering an effective amount of an agent that inhib its expression of neuropeptide Y (NPY). In another embodiment, the present invention provides a recombinant nucleic acid construct comprising a nucleic acid sequence encoding an oligonucleic acid, wherein the oligonucleic acid comprises at least one sequence substantially complementary to at least a part of the neuropeptide Y (NPY) gene or transcript thereof, and wherein the oligonucleic acid inhibits or reduces the expression of NPY.

Abstract: Disclosed are 3-aryl-6-aryl-[1,2,4]triazolo[4,3-?]pyridines thereof, represented by the Formula (I) wherein Ar1, Ar2, R1—R3 are defined herein. Compounds having Formula (I) are inhibitors of cell proliferation. Therefore, compounds of the invention may be used to treat clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.

Abstract: A position locking device is disclosed for a draw-out circuit breaker. In at least one embodiment, the position locking device includes a screw rod, a catching plate, a positioning plate, a locking plate, and a push rod. The screw rod has key ways. The catching plate has a catching plate hole and a protrusion that can be inserted into the key ways. Positioning notches for limiting OFF, TEST, and ON positions of the circuit breaker are formed on the top surface of the positioning plate, and corresponding protruding platforms are disposed on the bottom surface. One end of the locking plate bears against the bottom surface of the positioning plate, and the other end is locked to or unlocked from an outward protruding platform of the catching plate. One end of the push rod passes through the catching plate hole, and has an inclined surface. When the push rod is pushed, the inclined surface makes the catching plate leave the key ways.

Abstract: A position locking device is disclosed for a draw-out circuit breaker. In at least one embodiment, the position locking device includes a screw rod, a catching plate, a positioning plate, a locking plate, and a push rod. The screw rod has key ways. The catching plate has a catching plate hole and a protrusion that can be inserted into the key ways. Positioning notches for limiting OFF, TEST, and ON positions of the circuit breaker are farmed on the top surface of the positioning plate, and corresponding protruding platforms are disposed on the bottom surface. One end of the locking plate bears against the bottom surface of the positioning plate, and the other end is locked to or unlocked from an outward protruding platform of the catching plate. One end of the push rod passes through the catching plate hole, and has an inclined surface. When the push rod is pushed, the inclined surface makes the catching plate leave the key ways.

Abstract: A crank handle apparatus for a draw-out circuit breaker is disclosed. In at least one embodiment, the crank handle apparatus includes a crank, a locating piece, a button, a locking plate provided with a projecting part, and a retractable connecting link. A taken-in locking slot and a draw-out locking slot are provided in both ends of the crank. The locating piece includes a drawing gear which is wedged into the taken-in locking slot and the drawn-out locking slot respectively, and a locating slope which is connected with a locating spring apparatus. A button slope is provided in the button. A first resetting spring apparatus is provided in the button slope. A slope part of the button slope and a slope part of the locating slope are opposite and are in contact with each other. The projecting part is suppressed against or departed from the locating piece when the locking plate is moved.