Patents by Inventor Sheng-hung Kuo
Sheng-hung Kuo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150174301Abstract: This invention is related to the use of polyurethane based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs. The drug delivery device for releasing one or more drugs at controlled rates for an extended period of time to produce local or systemic pharmacological effects comprises: 1. a reservoir, said reservoir comprising; 2. at least one active ingredient; and, optionally, 3. at least one pharmaceutically acceptable carrier, a polyurethane based polymer completely surrounding the reservoir.Type: ApplicationFiled: January 30, 2015Publication date: June 25, 2015Applicant: BRAEBURN PHARMACEUTICAL BVBA SPRLInventors: Sheng-hung KUO, Petr Kuzma
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Publication number: 20140135684Abstract: This invention is related to the use of polyurethane based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs. The drug delivery device for releasing one or more drugs at controlled rates for an extended period of time to produce local or systemic pharmacological effects comprises: 1. a reservoir, said reservoir comprising; 2. at least one active ingredient; and, optionally, 3. at least one pharmaceutically acceptable carrier; a polyurethane based polymer completely surrounding the reservoir.Type: ApplicationFiled: January 20, 2014Publication date: May 15, 2014Applicant: Endo Pharmaceuticals Solutions Inc.Inventors: Sheng-hung Kuo, Petr Kuzma
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Patent number: 8658195Abstract: This invention is related to the use of polyurethane based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs. The drug delivery device for releasing one or more drugs at controlled rates for an extended period of time to produce local or systemic pharmacological effects comprises: 1. a reservoir, said reservoir comprising; 2. at least one active ingredient; and, optionally, 3. at least one pharmaceutically acceptable carrier; a polyurethane based polymer completely surrounding the reservoir.Type: GrantFiled: July 26, 2013Date of Patent: February 25, 2014Assignee: Endo Pharmaceuticals Solutions Inc.Inventors: Sheng-hung Kuo, Petr Kuzma
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Publication number: 20130310740Abstract: This invention is related to the use of polyurethane based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs. The drug delivery device for releasing one or more drugs at controlled rates for an extended period of time to produce local or systemic pharmacological effects comprises: 1. a reservoir, said reservoir comprising; 2. at least one active ingredient; and, optionally, 3. at least one pharmaceutically acceptable carrier; a polyurethane based polymer completely surrounding the reservoir.Type: ApplicationFiled: July 26, 2013Publication date: November 21, 2013Applicant: Endo Pharmaceuticals Solutions Inc.Inventors: Sheng-hung KUO, Petr Kuzma
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Patent number: 8529936Abstract: This invention is related to the use of polyurethane based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs. The drug delivery device for releasing one or more drugs at controlled rates for an extended period of time to produce local or systemic pharmacological effects comprises: 1. a reservoir, said reservoir comprising; 2. at least one active ingredient; and, optionally, 3. at least one pharmaceutically acceptable carrier; a polyurethane based polymer completely surrounding the reservoir.Type: GrantFiled: December 4, 2012Date of Patent: September 10, 2013Assignee: Endo Pharmaceuticals Solutions Inc.Inventors: Sheng-hung Kuo, Petr Kuzma
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Patent number: 8357389Abstract: This invention is related to the use of polyurethane based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs. The drug delivery device for releasing one or more drugs at controlled rates for an extended period of time to produce local or systemic pharmacological effects comprises: 1. a reservoir, said reservoir comprising; 2. at least one active ingredient; and, optionally, 3. at least one pharmaceutically acceptable carrier; a polyurethane based polymer completely surrounding the reservoir.Type: GrantFiled: August 31, 2010Date of Patent: January 22, 2013Assignee: Endo Pharmaceuticals Solutions Inc.Inventors: Sheng-hung Kuo, Petr Kuzma
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Patent number: 8343528Abstract: This invention is related to the use of polyurethane based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs. The drug delivery device for releasing one or more drugs at controlled rates for an extended period of time to produce local or systemic pharmacological effects comprises: 1. a reservoir, said reservoir comprising; 2. at least one active ingredient; and, optionally, 3. at least one pharmaceutically acceptable carrier; a polyurethane based polymer completely surrounding the reservoir.Type: GrantFiled: October 19, 2010Date of Patent: January 1, 2013Assignee: Endo Pharmaceuticals Solutions Inc.Inventors: Sheng-hung Kuo, Petr Kuzma
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Patent number: 8206734Abstract: This invention is related to the use of polyurethane based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs. The drug delivery device for releasing one or more drugs at controlled rates for an extended period of time to produce local or systemic pharmacological effects comprises: 1. a reservoir, said reservoir comprising; 2. at least one active ingredient; and, optionally, 3. at least one pharmaceutically acceptable carrier; a polyurethane based polymer completely surrounding the reservoir.Type: GrantFiled: August 31, 2010Date of Patent: June 26, 2012Assignee: Endo Pharmaceuticals Solutions Inc.Inventors: Sheng-hung Kuo, Petr Kuzma
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Publication number: 20110059147Abstract: This invention is related to the use of polyurethane based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs. The drug delivery device for releasing one or more drugs at controlled rates for an extended period of time to produce local or systemic pharmacological effects comprises: 1. a reservoir, said reservoir comprising; 2. at least one active ingredient; and, optionally, 3. at least one pharmaceutically acceptable carrier; a polyurethane based polymer completely surrounding the reservoir.Type: ApplicationFiled: August 31, 2010Publication date: March 10, 2011Inventors: Sheng-hung KUO, Petr Kuzma
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Publication number: 20110034566Abstract: This invention is related to the use of polyurethane based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs. The drug delivery device for releasing one or more drugs at controlled rates for an extended period of time to produce local or systemic pharmacological effects comprises: 1. a reservoir, said reservoir comprising; 2. at least one active ingredient; and, optionally, 3. at least one pharmaceutically acceptable carrier; a polyurethane based polymer completely surrounding the reservoir.Type: ApplicationFiled: October 19, 2010Publication date: February 10, 2011Inventors: Sheng-hung KUO, Petr Kuzma
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Patent number: 7842303Abstract: This invention is related to the use of polyurethane based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs. The drug delivery device for releasing one or more drugs at controlled rates for an extended period of time to produce local or systemic pharmacological effects comprises: 1. a reservoir, said reservoir comprising; 2. at least one active ingredient; and, optionally, 3. at least one pharmaceutically acceptable carrier; a polyurethane based polymer completely surrounding the reservoir.Type: GrantFiled: August 10, 2004Date of Patent: November 30, 2010Assignee: Indevus Pharmaceuticals, Inc.Inventors: Sheng-hung Kuo, Petr Kuzma
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Publication number: 20090208540Abstract: This invention is related to the use of polyurethane-based polymer as a drug delivery device to deliver naltrexone and formulations thereof at a constant rate for an extended period of time. The devices and methods of use thereof are biocompatible and biostable, and useful for the delivery of naltrexone in patients (humans and animals).Type: ApplicationFiled: January 9, 2009Publication date: August 20, 2009Inventors: Petr Kuzma, Harry Quandt, Sheng-hung Kuo
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Publication number: 20050037078Abstract: This invention is related to the use of polyurethane based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs. The drug delivery device for releasing one or more drugs at controlled rates for an extended period of time to produce local or systemic pharmacological effects comprises: 1. a reservoir, said reservoir comprising; 2. at least one active ingredient; and, optionally, 3. at least one pharmaceutically acceptable carrier; a polyurethane based polymer completely surrounding the reservoir.Type: ApplicationFiled: August 10, 2004Publication date: February 17, 2005Applicant: Valera PharmaceuticalsInventors: Sheng-hung Kuo, Petr Kuzma
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Patent number: 5952422Abstract: Method for forming a polyurethane based adhesive composition in which a reaction mixture of at least one NCO-terminated prepolymer and a polyhydroxy compound is heated at a temperature and for a length of time sufficient to provide a gel content of from about 30 to 42% by weight and a molecular weight of extractables of at least about 45,000. Polyurethane based adhesives prepared by the method and medical devices employing the same are also disclosed.Type: GrantFiled: December 18, 1996Date of Patent: September 14, 1999Assignee: Bristol-Myers Squibb CompanyInventors: Tak-lung Chang, Sheng-hung Kuo, Kishore Shah, Agis Kydonieus
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Patent number: 5591820Abstract: Pressure-sensitive adhesives which possess absorptivity and/or permeability properties to remove transepidermal water loss and/or other bodily fluids that come into contact with the adhesive, in combination with a fine balance of cohesion and adhesion properties, can be formulated by controlling the crosslinking of a polyurethane polymer having excess hydroxyl functionality, a glass transition temperature of less than about 0.degree. C., a moisture absorption of at least about 20% of its weight and/or a moisture vapor transmission rate of at least about 300 grams/meter.sup.2 /24 hours measured at 37.degree. C. and a 90% relative humidity gradient. Adhesives of these polymers possess a peel adhesion to human skin of between about 0.3 and 4 newtons/cm width of the polymer or adhesive.Type: GrantFiled: May 9, 1995Date of Patent: January 7, 1997Assignee: E. R. Squibb & Sons, Inc.Inventors: Agis Kydonieus, Ladislav Bastar, Kishore Shah, Khosrow Jamshidi, Tak-lung Chang, Sheng-hung Kuo