Patents by Inventor Sheng-Hung Rainbow Tschang

Sheng-Hung Rainbow Tschang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multifunctional antibodies binding to EGFR and MET
    Patent number: 9328173
    Abstract: Provided are multifunctional antibodies, and/or antigen-binding fragments, that bind to, and inhibit the activity of, both human epidermal growth factor receptor (EGFR) and MET, and that are effective in treating cancers and other diseases, disorders, or conditions where pathogenesis is mediated by EGFR and MET.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: May 3, 2016
    Assignee: Eli Lilly and Company
    Inventors: Hector Aldaz, Barrett Allan, Ling Liu, Jirong Lu, Ying Tang, Sheng-Hung Rainbow Tschang, Pia Pauliina Yachi
  • Multifunctional Antibodies Binding to EGFR and MET
    Publication number: 20150175708
    Abstract: Provided are multifunctional antibodies, and/or antigen-binding fragments, that bind to, and inhibit the activity of, both human epidermal growth factor receptor (EGFR) and MET, and that are effective in treating cancers and other diseases, disorders, or conditions where pathogenesis is mediated by EGFR and MET.
    Type: Application
    Filed: December 17, 2014
    Publication date: June 25, 2015
    Inventors: Hector ALDAZ, Barrett ALLAN, Ling LIU, Jirong LU, Ying TANG, Sheng-Hung Rainbow TSCHANG, Pia Pauliina YACHI
  • FGF-21 fusion proteins
    Patent number: 7576190
    Abstract: The invention provides specific FGF-21 compounds fused to specific IgG4-Fc or HSA derivatives resulting in fusion proteins that are biologically active with an extended elimination half-life and a slower clearance. These FGF-21 compound fusion proteins and compositions are useful in treating type 2 diabetes, obesity, and metabolic syndrome.
    Type: Grant
    Filed: May 2, 2005
    Date of Patent: August 18, 2009
    Assignee: Eli Lilly and Company
    Inventors: Wolfgang Glaesner, Rohn Lee Millican, Jr., Yu Tian, Sheng-Hung Rainbow Tschang
  • GLP-1 fusion proteins
    Patent number: 7271149
    Abstract: The present invention relates to glucagon-like-1 compounds fused to proteins that have the effect of extending the in vivo half-life of the peptides. These fusion proteins can be used to treat non-insulin dependent diabetes mellitus as well as a variety of other conditions.
    Type: Grant
    Filed: November 29, 2001
    Date of Patent: September 18, 2007
    Assignee: Eli Lilly and Company
    Inventors: Wolfgang Glaesner, Radmila Micanovic, Sheng-Hung Rainbow Tschang
  • Flint polypeptide analogs
    Patent number: 6965012
    Abstract: Disclosed are polypeptide analogs of FLINT, polydeoxynucleotides encoding FLINT analogs, and methods of using FLINT analogs and polydeoxynucleotides. The FLINT analogs of the invention include polypeptides having the amino acid sequence of FLINT, modified at one or more positions with amino acid substitutions, and include fragments thereof, as well as Fc fusions comprising FLINT and FLINT analogs.
    Type: Grant
    Filed: March 20, 2000
    Date of Patent: November 15, 2005
    Assignee: Eli Lilly and Company
    Inventors: Gerald Wayne Becker, Fredric Jay Cohen, Patricia Ann Gonzalez-DeWhitt, John Edward Hale, Radmila Micanovic, Christy Michelle Newton, Timothy Wayne Noblitt, Radhakrishnan Rathnachalam, Sheng-Hung Rainbow Tschang, Derrick Ryan Witcher, Victor John Wroblewski
  • GLP-1 Fusion Proteins
    Publication number: 20040053370
    Abstract: The present invention relates to glucagon-like-1 compounds fused to proteins that have the effect of extending the in vivo half-life of the peptides. These fusion proteins can be used to treat non-insulin dependent diabetes mellitus as well as a variety of other conditions.
    Type: Application
    Filed: May 29, 2003
    Publication date: March 18, 2004
    Inventors: Wolfgang Glaesner, Radmila Micanovic, Sheng-Hung Rainbow Tschang
  • Novel secreted proteins and their uses
    Publication number: 20040038242
    Abstract: The present invention provides nucleic acid sequences encoding novel human proteins. These novel nucleic acids are useful for constructing the claimed DNA vectors and host cells of the invention and for preparing the claimed nucleic acids, recombinant proteins and antibodies that are useful in the claimed methods and medical uses.
    Type: Application
    Filed: January 29, 2003
    Publication date: February 26, 2004
    Inventors: Brian Taylor Edmonds, Radmila Micanovic, Weijia Ou, Eric Wen Su, Sheng-Hung Rainbow Tschang, He Wang