Patents by Inventor Sheng-Shung Pong

Sheng-Shung Pong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cloning and identification of the motilin receptor
    Patent number: 7179886
    Abstract: The motilin receptor has been isolated and cloned, and nucleic acid sequences are given. Two spice variants have been identified. Also, assays for motilin receptor ligands are given. The identification of the cloned motilin receptor may be used to screen and identify compounds which bind to the receptor for use in a variety of gastric conditions, including gastric motility disorders.
    Type: Grant
    Filed: June 8, 1999
    Date of Patent: February 20, 2007
    Assignee: Merck & Co., Inc.
    Inventors: Scott D. Feighner, Arthur A. Patchett, Carina Tan, Karen Kulju McKee, Douglas MacNeil, Andrew D. Howard, Sheng-Shung Pong, Roy G. Smith
  • Assays for growth hormone secretagogue receptors
    Patent number: 6242199
    Abstract: An assay for the detection of growth hormone secretagogue receptors and growth hormone secretagogue related receptors is described. As these receptors are a member of the G protein coupled receptors, a subunit of the G protein must be present in order for expression to be detected. A similar assay is described where the presence of growth hormone secretagogues are detected.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: June 5, 2001
    Assignee: Merck & Co., Inc.
    Inventors: Lee-Yuh Pai, Scott D. Feighner, Andrew D. Howard, Sheng-Shung Pong, Leonardus H. T. Van Der Ploeg
  • Radiolabeled growth hormone secretagogue
    Patent number: 5830433
    Abstract: The present invention is directed to ?.sup.35 S!-N-?1(R)-?(1,2-dihydro-1-methanesulfonylspiro?3H-indole-3,4'-piperidin!- 1'-yl)carbonyl!-2-(phenylmethyloxy)ethyl!-2-amino-2-methylpropanamide, and pharmaceutically acceptable salts thereof. This ?.sup.35 S! radioligand is useful in identifying and characterizing cellular receptors which play a role in the activity of growth hormone secretatogogues. In addition, this ?.sup.35 S! radioligand is useful in assays which test compounds for growth hormone secretagogue activity.
    Type: Grant
    Filed: December 17, 1996
    Date of Patent: November 3, 1998
    Assignee: Merck & Co., Inc.
    Inventors: Dennis C. Dean, David G. Melillo, Ravi Nargund, Leonardus Van Der Ploeg, Sheng-Shung Pong, James M. Schaeffer, Roy G. Smith