Abstract: A computer-implemented method dynamically switches access plans for a query during concurrent query execution. The method includes receiving a first query configured to be processed by a database system. The method also includes generating, for the first query, an access plan for each of identified resource sets. The method includes determining a first set of available resources that represent an available capacity for the database system. The method further includes selecting a first resource set of the one or more resource sets, where the selecting is based on the first set of available resources being closest to the first resource set. The method also includes selecting, based on the first set of available resources, a first access plan of the one or more access plans. The method includes executing the first query and returning results of the first query to a source of the first query.

Abstract: The compositions and methods described herein are based, in part, on the discovery that regulatory B cells (Bregs) differentially express a specific set of coinhibitory molecules, including TIGIT, LAG-3, PD-1, CTLA4, and TIM-3. The data described herein indicate that TIGIT is required for both Breg-mediated tolerance maintenance at the steady state, and inflammation restraint during autoimmune and inflammatory diseases. Accordingly, provided herein are compositions and methods targeting coinhibitory molecules, such as TIGIT, LAG-3, PD-1, CTLA4, and TIM-3, in B cells, as novel therapeutic strategies for modulating immune suppression and treating diseases mediated or impacted by immune suppression mechanisms, such as autoimmune diseases and cancers.

Abstract: A tracking device is described. The tracking device receives, from a management server, pressure measurement thresholds. The tracking device monitors pressure measurements of the asset. Based on the pressure measurements, the tracking device enters an active mode of operation. When operating in the active mode of operation, the tracking device transmits sensor measurements of the asset to the management server. The tracking device determines new pressure measurements of the asset. Based on the new pressure measurements, the tracking device enters a passive mode of operation. When operating in the passive mode of operation, no data is transmitted or received from/to the tracking device to/from the management server.

Abstract: An iron-based metal powder for ultra-high-speed laser cladding comprising chemical composition and mass percentage of the metal powder of: C 0.6˜1.0%, Cr 17.0˜20.0%, Ni 5.0˜6.5%, Mn 2.0˜4.0%, Mo 1.0˜1.5%, Ti 4.0˜6.0%, B 1.0˜1.5%, N 0.08˜0.15%, Si?0.5%, P?0.030%, S?0.030%, balance of Fe and unavoidable impurities, wherein the particle size of the metal powder is 15˜65 ?m, the fluidity is 16˜20 s/50 g.

Abstract: Provided herein are free base crystalline forms, crystalline salts, and an amorphous salts of omecamtiv mecarbil.

Abstract: An electrostatic protection structure able to discharge static electricity of either polarity from a functional circuit including signal lines includes a discharge electrode and a plurality of electrostatic protection units electrically coupled to the discharge electrode. Each electrostatic protection unit includes a first TFT and a second TFT. The first TFT includes first gate, source, and drain, the second TFT includes second gate, source, and drain. The first gate and the first drain are electrically connected to one signal line. The first source is electrically connected to the second drain, the first drain is electrically connected to the second source, the second gate is electrically connected to the discharge electrode, and the second gate is electrically connected to the second drain.

Abstract: A thin film transistor substrate allowing an increase in proportionate size of the display area includes gate driving units, signal test pads, a first function line, and a first-stage gate output signal line in a surrounding non-display area, the display area having pixels. The gate driving units include a first-stage gate driving unit with an output terminal electrically connected to one row of pixels. The first function line has a first function but can also multiplex as a connecting line between the first-stage gate output signal line and one test pad. The first-stage gate output signal line is electrically insulated from the first function line during the first function of the first function line but is electrically connected to the first function line when multiplexed.

Abstract: Provided herein are methods and compositions related to the targeting of Bregs for the treatment of diseases and disorders involving inappropriate suppression of B cell-mediated immune function.

Abstract: A thin film transistor substrate allowing an increase in proportionate size of the display area includes gate driving units, signal test pads, a first function line, and a first-stage gate output signal line in a surrounding non-display area, the display area having pixels. The gate driving units include a first-stage gate driving unit with an output terminal electrically connected to one row of pixels. The first function line has a first function but can also multiplex as a connecting line between the first-stage gate output signal line and one test pad. The first-stage gate output signal line is electrically insulated from the first function line during the first function of the first function line but is electrically connected to the first function line when multiplexed.

Abstract: An electrostatic protection structure able to discharge static electricity of either polarity from a functional circuit including signal lines includes a discharge electrode and a plurality of electrostatic protection units electrically coupled to the discharge electrode. Each electrostatic protection unit includes a first TFT and a second TFT. The first TFT includes first gate, source, and drain, the second TFT includes second gate, source, and drain. The first gate and the first drain are electrically connected to one signal line. The first source is electrically connected to the second drain, the first drain is electrically connected to the second source, the second gate is electrically connected to the discharge electrode, and the second gate is electrically connected to the second drain.

Abstract: A thin film transistor (TFT) substrate optimized for protection against the build up of static electricity defines a display area and a non-display area surrounding the display area. The TFT substrate includes a substrate and an electrostatic protection structure on the substrate and in the non-display area. The electrostatic protection structure includes a transparent conductive layer and a discharge metal layer on the transparent conductive layer. The discharge metal layer partially overlaps with the transparent conductive layer. The discharge metal layer is in direct contact with the transparent conductive layer. The transparent conductive layer has a width that is greater than a width of the discharge metal layer.

Abstract: A Multi-Z confocal microscopy system can simultaneously record from multiple Z-sections, and thus performs high speed volumetric imaging. An illumination line can be formed by under-filling the illumination beam in the aperture of the microscope objective. The illumination line extends in the Z dimension into the target sample to be imaged and an X-Y scanning mechanism can be used to scan the illumination line over the sample. The detection signal emanating from the scanned sample can be collected through the full numerical aperture of the microscope objective and directed to a detector subsystem. The detector subsystem includes an array of reflecting pinhole detectors and each reflecting pinhole detector is configured to image a volume at a different depth in the sample. This configuration enables reflecting pinhole detector array to image more than one depth volume at the same time.

Abstract: The compositions and methods described herein are based, in part, on the discovery that regulatory B cells (Bregs) differentially express a specific set of coinhibitory molecules, including TIGIT, LAG-3, PD-1, CTLA4, and TIM-3. The data described herein indicate that TIGIT is required for both Breg-mediated tolerance maintenance at the steady state, and inflammation restraint during autoimmune and inflammatory diseases. Accordingly, provided herein are compositions and methods targeting coinhibitory molecules, such as TIGIT, LAG-3, PD-1, CTLA4, and TIM-3, in B cells, as novel therapeutic strategies for modulating immune suppression and treating diseases mediated or impacted by immune suppression mechanisms, such as autoimmune diseases and cancers.

Abstract: A Multi-Z confocal microscopy system can simultaneously record from multiple Z-sections, and thus performs high speed volumetric imaging. An illumination line can be formed by under-filling the illumination beam in the aperture of the microscope objective. The illumination line extends in the Z dimension into the target sample to be imaged and an X-Y scanning mechanism can be used to scan the illumination line over the sample. The detection signal emanating from the scanned sample can be collected through the full numerical aperture of the microscope objective and directed to a detector subsystem. The detector subsystem includes an array of reflecting pinhole detectors and each reflecting pinhole detector is configured to image a volume at a different depth in the sample. This configuration enables reflecting pinhole detector array to image more than one depth volume at the same time.

Abstract: The invention relates to the field of semiconductor, more particularly, to a preparation process of image sensors, comprising: Step S1, providing a semiconductor structure, a top of which is provided with a groove, and leads being formed in said groove, the top of said semiconductor structure and an exposed surface of said groove are covered with a first dielectric layer; Step S2: depositing a second dielectric layer covering the upper surface of said first dielectric layer and said leads and filling said groove; Step S3: performing a reversed-etching process to thin said second dielectric layer, and to form a convex structure on a surface of said second dielectric layer above the groove; Step S4: performing a planarization process to said second dielectric layer to improve surface evenness of said second dielectric layer after grinding by the convex structure.

Abstract: The invention relates to the field of semiconductor, more particularly, to a preparation process of image sensors, comprising: Step S1, providing a semiconductor structure, a top of which is provided with a groove, and leads being formed in said groove, the top of said semiconductor structure and an exposed surface of said groove are covered with a first dielectric layer; Step S2: depositing a second dielectric layer covering the upper surface of said first dielectric layer and said leads and filling said groove; Step S3: performing a reversed-etching process to thin said second dielectric layer, and to form a convex structure on a surface of said second dielectric layer above the groove; Step S4: performing a planarization process to said second dielectric layer to improve surface evenness of said second dielectric layer after grinding by the convex structure.

Abstract: The invention relates to the field of semiconductor manufacturing process, more particularly, to an image sensor having an embedded color filter and its preparation method, providing a bonded wafer with leads, and performing preparation process of metal insulated gates and embedding process of color filters on bonded wafers, etching to expose the opening of the lead, and eventually combining color filter process with lead process; the implementation of the invention is simple, implementation difficulty is relatively small, and can greatly improve the transmission speed of output image signal and image quality, at the same time, the technical scheme can be used in front-illuminated, back-illuminated and stackable image sensors, etc.

Abstract: This disclosure provides methods and servers to transmit data packets via Transmission Control Protocol (TCP) connections. In some aspects, transmitting data packets includes receiving a data packet from a first application on a first server. The data packet is analyzed to determine a destination address associated with a second server. The data packet is transmitted based on the address associated with the second server. In some aspects, transmitting data packets includes receiving a data packet from a second application on a second server. The data packet is analyzed to determine the destination address associated with a first application on the first server. The data packet is transmitted based on the address associated with the first application. In some aspects, transmitting data packets includes a flow control mechanism to control data transmission.

Abstract: This disclosure provides methods and servers to transmit data packets via Transmission Control Protocol (TCP) connections. In some aspects, transmitting data packets includes receiving a data packet from a first application on a first server. The data packet is analyzed to determine a destination address associated with a second server. The data packet is transmitted based on the address associated with the second server. In some aspects, transmitting data packets includes receiving a data packet from a second application on a second server. The data packet is analyzed to determine the destination address associated with a first application on the first server. The data packet is transmitted based on the address associated with the first application. In some aspects, transmitting data packets includes a flow control mechanism to control data transmission.

Abstract: The present invention provides systems and methods for securing communications in a wireless network by utilizing the inherent randomness of propagation errors to enable legitimate users to dynamically create a shared symmetric secret key. In one embodiment, the invention provides a system with two computers each having a wireless network adapter. The sending node encodes the frames, transmits the frames, determines if the frames were correctly received, retransmits the frames if they were not correctly received, stores the frames that were not retransmitted, and uses the stored frames to generate a secret key. The receiving node receives the encoded frames, determines if the frames were retransmitted, stores at least one of the frames that was not retransmitted, and uses the stored frames to generate the same secret key as the receiving node.