Abstract: A method for preparing ginseng extract rich in rare ginsenosides is disclosed. Ginseng roots or ginseng stems and leaves are extracted, enzymatically hydrolyzed and treated with high temperature and high pressure. The preparation method can quickly and effectively increase the proportion of rare ginsenosides in the ginseng extract. After in vitro antioxidant experiments and in vivo experiments with Hidradenitis elegans nematode, the extract and related complexes were proved to be effective in antioxidant, anti-oxidative stress, and improving age-related muscle decline and other dysfunctions. After genetic and metabolomic studies, the anti-aging mechanism was proved to be related to the expression of genes associated with nutrient sensing, stress-related pathways and redox processes, and showed innate immune response and redox process GO enrichment, proving its oxidative stress resistance.

Abstract: The present invention belongs to the field of drug preparation and detection, and particularly discloses a preparation method for a Eucommia ulmoides Oliv. leaf extract. The extract is obtained from Eucommia ulmoides Oliv. leaves (the mixture of the Eucommia ulmoides Oliv. leaves and Eucommia ulmoides Oliv. male flower) by enzymolysis and extraction of ethanol and water, and can effectively solve the problem that the extract is not easy to spray dry (the Eucommia ulmoides Oliv. leaves contain colloidal substances). The pharmacodynamic experiment proves that the Eucommia ulmoides Oliv. leaf extract has good effect of protecting the health of the renal function. The present invention also develops a detection method for the extract, which not only realizes the quality control of the extract, but also has the advantages of good repeatability and stability.

Abstract: A resveratrol composition and its preparation method and application are disclosed, which relates to the technical field of resveratrol solid dispersion preparation. A resveratrol composition is prepared from following raw materials: 6%-60% by weight of resveratrol, and 40%-94% by weight of poloxamer. The disclosure mixes the resveratrol and poloxamer in proportion to prepare a composition, and further improves the dissolution and bioavailability of the resveratrol in combination with microencapsulation technology. The preparation process is suitable for industrialization and has good application and promotion prospects.

Abstract: A debittering Kudingcha extract, a preparation method and a fingerprint detection method thereof are disclosed, which relates to the technical field of extract preparation and detection. The extract is prepared from Kudingcha by enzymolysis, water extraction, concentration, drying, purification and enrichment by a macroporous resin column, and drying. When the macroporous resin column is arranged for purification and enrichment, it is first rinsed with pure water, and then eluted with an ethanol solution with volume fraction of 30-80%, and an ethanol eluent is collected. The Kudingcha extract is purified with macroporous resin, which can retain its effective ingredients to the greatest extent while reducing the bitter taste, and enhance the effect of improving energy and resisting fatigue. The quality control of products through fingerprint is conducive to the improvement of product stability and further promotion of products.

Abstract: An antidepressant compound preparation and a preparation method for same were disclosed, The antidepressant includes the following raw materials of Hypericum perforatum L., Paeonia lactiflora Pall., Gardenia jasminoides Ellis, Albizia julibrissin Durazz. and Moutan cortex. The raw materials are weighed in proportion to obtain extracts respectively, and the extracts are mixed to prepare a compound preparation. The compound preparation prepared by the present invention has the advantages of simple preparation, safety, low toxic and side effects, no dependence, etc., and can effectively alleviate depression mood.

Abstract: The present disclosure relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine extract composition with function of regulating depressive emotion and preparation method and traditional Chinese medicine preparation thereof. The composition consists of the following traditional Chinese medicine extracts in parts by weight: 40-80 parts of Hypericum perforatum extract, 10-40 parts of Acanthopanax senticosus extract, and 2-20 parts of Tree peony root bark extract. Compared with the prior art, the traditional Chinese medicine extract composition of the present disclosure has remarkable effect of alleviating depressive emotion, and is a safe and effective dietary supplement. In addition, it also has the effect of helping sleep. The composition has small side effects and no dependence, has a small dosage, and can be made into various dosage forms suitable for wide application.

Abstract: This application belongs to the field of biotechnology and discloses a method for producing a clam active peptide. The method for producing a clam active peptide comprises cleaning fresh clam meat with water, adding water and homogenizing with a colloid mill to prepare a clam meat slurry; adding water and complex protease for enzymolysis of the clam meat slurry, and heating to inactivate enzyme after the enzymolysis; centrifuging to collect an enzymatic hydrolyzate, capturing the enzymatic hydrolyzate having a molecular weight of lower than 2 KDa through microfiltration-ultrafiltration-nanofiltration membrane filtration, and drying to obtain the clam active peptide.

Abstract: The present invention discloses a method for product quality control and fingerprint detection of an epimedium brevicornu complex. The method uses high performance liquid chromatography, and can effectively realize the quality control of products containing traditional Chinese medicine components, and especially stable control of the quality of products containing a large quantity of non-traditional Chinese medicine components in formulas. Through step-by-step quality control, product quality fluctuation is reduced and stable quality is ensured. Meanwhile, the method is simple and convenient, does not need additional instruments and standards, saves the cost and is more conducive to actual production.

Abstract: A traditional Chinese medicine composition includes 60%-80% by weight of Eucommia ulmoides extract, 15%-30% by weight of Rhizoma Drynariae extract and 5%-10% by weight of Semen Cuscutae extract. A method of preparing the traditional Chinese medicine composition is also provided. Uses of the traditional Chinese medicine composition in the prevention and/or treatment of osteoporosis are also provided.

Abstract: A traditional Chinese medicine compound composition with effect of improving male sexual function and its application are disclosed. The disclosure prepares the traditional Chinese medicine compound composition by compounding Semen Allii Tuberosi with Radix Morindae Officinalis, Epimedii Folium, Cistanche deserticola Ma and Semen Cuscutae. The traditional Chinese medicine compound composition has a good effect on improving the sexual function of kidney Yang deficiency model mice. While improving sexual function, it can improve the abundance of spermatogenic cells in testicular seminiferous tubules, ensure that spermatogenic cells can continuously produce new sperm, and improve the number and morphology of sperm in the lumen. Moreover, the disclosed traditional Chinese medicine compound composition can be used as a raw material of dietary supplement or health food for the male population with low sexual function and easy fatigue.

Abstract: A method for establishing fingerprint of traditional Chinese medicine compound or its preparation with improving cognition is disclosed. By weight, the traditional Chinese medicine compound is made from following raw materials: 1-20 parts of Gastrodiae Rhizoma, 1-15 parts of Polygala tenuifolia, 1-30 parts of Acorus tatarinowii, 0.1-10 parts of Cistanche deserticola Ma, 0.1-10 parts of Rehmanniae Radix Praeparata, and 0.01-1 parts of curcumin. A chromatogram of a test sample solution is established by high performance liquid chromatography. Chromatographic conditions are as follows: a chromatographic column is octadecyl silane bonded silica gel chromatographic column. A column temperature is 25˜35 ° C. A flow rate is 0.9˜ 1.1 ml/min. Detection wavelengths are 210˜230 nm and 310˜330 nm respectively. A mobile phase A is acetonitrile and a mobile phase B is water. And gradient elution is carried out.

Abstract: A curcumin complex, a preparation method therefor and a detection method therefor, the curcumin complex comprising a solid complex formed by grinding auxiliary material and curcumin, the auxiliary material comprising Soluplus, poloxamer 407, or poloxamer 188; when the auxiliary material comprises the Soluplus, the mass ratio of the curcumin to the Soluplus is 1:8-10; and when the auxiliary material comprises the poloxamer 407 or poloxamer 188, the mass ratio of the curcumin to the poloxamer 407 is 1:0.4-0.6, and the mass ratio of the curcumin to the poloxamer 188 is 1:0.4-0.6. Also disclosed is a preparation method for a curcumin complex. The curcumin complex has high bioavailability and a simple prescription process; in addition, the crystal form of the curcumin is not changed, and not only is quality control more complete and reliable, but costs are also lower, and large-scale production is facilitated.

Abstract: A multi-efficacy traditional Chinese medicine compound composition and application thereof in pharmaceutical preparations are disclosed. The traditional Chinese medicine extracts are combined with the glucosamine, the collagen and the chondroitin sulfate, so that the multi-efficacy traditional Chinese medicine compound composition is prepared. The traditional Chinese medicine compound composition starts from improving the health of bone and joint and accompanying cardiovascular disease, selects the medicinal materials, and optimizes the extraction process of the traditional Chinese medicine for the diseases dominated by degenerative osteoarthritis. The disclosure has the efficacious of improving the symptoms of degenerative osteoarthritis, reducing blood pressure, improving the symptoms with osteoporosis, improving the symptoms with cardiovascular disease, improving the symptoms with urinary system disease, etc.

Abstract: The present disclosure relates to the technical field of traditional Chinese medicine, and more specifically, to a traditional Chinese medicine composition with improving cognition effect, its preparation method and a traditional Chinese medicine preparation. In parts by weight, the traditional Chinese medicine composition is made from 1-20 parts of Gastrodiae Rhizoma, 1-15 parts of Polygala tenuifolia Willd., 1-30 parts of Acorus tatarinowii, 0.1-10 parts of Cistanche deserticola Ma, 0.1-10 parts of Rehmanniae Radix Praeparata, and 0.01-1 parts of curcumin. The pharmacodynamic substances of Gastrodiae Rhizoma, Polygala tenuifolia Willd., Acorus tatarinowii, Cistanche deserticola Ma and Rehmanniae Radix Praeparata are extracted completely, concentrated and dried as much as possible. The volatile oil of Acorus tatarinowii and curcumin are encapsulated and dried by the volatile oil encapsulation technology.

Abstract: A curcumin compound composition and method for preparing the composition is disclosed. In order to improve the dissolution and bioavailability of curcumin, the compound composition is prepared by mixing curcumin and excipients according to a ratio, and the compound composition is prepared by tightly combining curcumin with glycerol monostearate and sodium carboxymethyl cellulose. The preparation process is suitable for industrialization, and the prepared compound composition has stable properties and improves the bioavailability of curcumin, and has good application and promotion prospects.

Abstract: A traditional Chinese medicine compound composition with immune bidirectional regulation effect and its preparation method and applications are disclosed. The traditional Chinese medicine compound composition with immune bidirectional regulation effect is prepared by compounding a volatile oil obtained after heating and refluxing of Schizonepetae herba and an extract jointly extracted by Schizonepetae herba extract residue, Astragali radix and Atractylodes macrocephala in the disclosure. The traditional Chinese medicine compound composition has no side effects and remarkable effect, and the traditional Chinese medicine compound composition disclosed by the disclosure can be used as a dietary supplement or health food raw material to regulate allergic reaction and low immunity. The traditional Chinese medicine compound composition disclosed by the disclosure is suitable for promotion and application.

Abstract: A traditional Chinese medicine compound composition with anti-anxiety effect and its preparation method and application are disclosed. The traditional Chinese medicine compound composition with anti-anxiety effect is prepared by compounding the Paeoniae Radix Alba extract, the Gardeniae Fructus extract, the Albiziae Flos extract and the Moutan Cortex extract. The traditional Chinese medicine compound composition has no toxic side effects and has remarkable treatment effect, and can be used as a dietary supplement or a health-care food ingredient to prevent and treat anxiety disorder, and promote mental health. It can be seen that the traditional Chinese medicine compound composition is suitable for promotion and application.

Abstract: An antidepressant compound preparation and a preparation method for same were disclosed, The antidepressant includes the following raw materials of Hypericum perforatum L., Paeonia lactiflora Pall., Gardenia jasminoides Ellis, Albizia julibrissin Durazz. and Moutan Cortex. The raw materials are weighed in proportion to obtain extracts respectively, and the extracts are mixed to prepare a compound preparation. The compound preparation prepared by the present invention has the advantages of simple preparation, safety, low toxic and side effects, no dependence, etc., and can effectively alleviate depression mood.

Abstract: A compound composition for improving bone health and preparation and application thereof are provided. The compound composition is prepared by combining a traditional Chinese medicine extract with chicken cartilage collagen, magnesium, vitamin K2 and vitamin D3. The compound composition overcomes the food safety risk of the existing osteoporosis preventive drugs by adding the traditional Chinese medicine extract for improving osteoporosis and promoting bone health. And the compound composition disclosed can be used as a dietary supplement or health food raw material for preventing or treating osteoporosis. Therefore, the compound composition disclosed is suitable for promotion and application.

Abstract: The present invention discloses a compound composition with function of promoting bone and joint health and an application thereof. In the present invention, glucosamine is combined with collagen, chondroitin sulfate and traditional Chinese medicine extract to prepare the compound composition with function of promoting bone and joint health. The compound composition can shorten onset time. At the same time, the traditional Chinese medicine extract for treating the bone and joint problems is added, to reduce the market impact of adding only modern joint health ingredients. Moreover, the compound composition disclosed by the present invention can be used as a dietary supplement or health food raw material for preventing or treating moderate to mild osteoarthritis. Thus, the compound composition disclosed by the present invention is suitable for promotion and application.