Patents by Inventor Shengguo Zhao

Shengguo Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12110544
    Abstract: In a method for extracting microbial DNA from milk, the extracted DNA can be directly used for PCR amplification. The method includes the following steps: treating milk with TE solution, fully disrupting microbial cells by bead milling, immobilizing proteins in the middle layer between the aqueous and organic phases with high-vacuum silicone grease so as to prevent impurities in the middle layer from entering the aqueous phase, etc. The extracted DNA has a high degree of intactness, high concentration and purity.
    Type: Grant
    Filed: July 13, 2018
    Date of Patent: October 8, 2024
    Assignee: INSTITUTE OF ANIMAL SCIENCES, CHINESE ACADEMY OF AGRICULTURAL SCIENCES
    Inventors: Jiaqi Wang, Shengguo Zhao, Nan Zheng, Xu Zhou, Songli Li
  • Patent number: 12031119
    Abstract: In a method for enriching and separating an anaerobic fiber-degrading bacterium on the basis of cellulosic magnetic nanoparticles, the cellulosic magnetic nanoparticles are prepared by coating cellulose on the surface of a magnetic nanomaterial. Bacteria attach to the cellulosic magnetic nanoparticles. Anaerobic fiber-degrading bacteria degrade the cellulose and then detach from the cellulosic magnetic nanoparticles, and the anaerobic fiber-degrading bacteria are obtained by means of separation using a magnet. The magnetic nano-separation technology can be used as a new technology to efficiently separate anaerobic fiber-degrading bacteria.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: July 9, 2024
    Assignee: INSTITUTE OF ANIMAL SCIENCES, CHINESE ACADEMY OF AGRICULTURAL SCIENCES
    Inventors: Shengguo Zhao, Jiaqi Wang, Nan Zheng, Lei Xing, Yangdong Zhang, Songli Li
  • Publication number: 20210292809
    Abstract: In a method for extracting microbial DNA from milk, the extracted DNA can be directly used for PCR amplification. The method includes the following steps: treating milk with TE solution, fully disrupting microbial cells by bead milling, immobilizing proteins in the middle layer between the aqueous and organic phases with high-vacuum silicone grease so as to prevent impurities in the middle layer from entering the aqueous phase, etc. The extracted DNA has a high degree of intactness, high concentration and purity.
    Type: Application
    Filed: July 13, 2018
    Publication date: September 23, 2021
    Inventors: Jiaqi WANG, Shengguo ZHAO, Nan ZHENG, Xu ZHOU, Songli LI
  • Publication number: 20210214674
    Abstract: In a method for enriching and separating an anaerobic fiber-degrading bacterium on the basis of cellulosic magnetic nanoparticles, the cellulosic magnetic nanoparticles are prepared by coating cellulose on the surface of a magnetic nanomaterial. Bacteria attach to the cellulosic magnetic nanoparticles. Anaerobic fiber-degrading bacteria degrade the cellulose and then detach from the cellulosic magnetic nanoparticles, and the anaerobic fiber-degrading bacteria are obtained by means of separation using a magnet. The magnetic nano-separation technology can be used as a new technology to efficiently separate anaerobic fiber-degrading bacteria.
    Type: Application
    Filed: July 12, 2018
    Publication date: July 15, 2021
    Inventors: Shengguo ZHAO, Jiaqi WANG, Nan ZHENG, Lei XING, Yangdong ZHANG, Songli LI
  • Publication number: 20190289879
    Abstract: The present disclosure provides a method for reducing zearalenone content in straw using steam explosion technology and use thereof, creatively utilizes the huge energy released during steam explosion, and destroys the chemical structure of zearalenone without introducing other harmful chemicals, wherein the steam explosion technology can be used as a completely new technology for reducing zearalenone content in straw.
    Type: Application
    Filed: March 21, 2019
    Publication date: September 26, 2019
    Inventors: Jiaqi Wang, Shengguo Zhao, Nan Zheng, Yangdong Zhang
  • Publication number: 20190042705
    Abstract: The invention relates to a realization method for computer-aided screening of target aptamers and small molecule compounds, which is realized by adopting a molecular docking technology-based reverse virtual screening algorithm and comprises the steps of generating random unrepeated sequences with an appointed length of n based on a sequence length input by a user; modeling a double-stranded DNA structure for each sequence in the random unrepeated sequences and generating a corresponding double-stranded DNA three-dimensional structure file; carrying out format transformation for each generated double-stranded DNA three-dimensional structure file to be used for molecular docking; carrying out format transformation for target small molecules to enable the processed target small molecules to be used for the molecular docking; carrying out molecular docking for each target small molecule and each aptamer; and reading the score files after the molecular docking by two matrix generation functions, and respectively g
    Type: Application
    Filed: June 16, 2016
    Publication date: February 7, 2019
    Applicant: INSTITUTE OF ANIMAL SCIENCE OF CHINESE ACADEMY OF AGRICULTURAL SCIENCES
    Inventors: Nan Zheng, Ming Li, Jiaqi Wang, Yangdong Zhang, Fang Wen, Songli Li, Shengguo Zhao