Abstract: A method for inducing mass apoptosis of cancer cells by enhancing the overall acidity in the tumor. The method enhances overall acidity in tumor internal tissue to reduce overall pH in tumor tissue, last to induce mass apoptosis of cancer cells. When pH of extracellular micro-environment of cancer cells is lower than 5.0, mass apoptosis of cancer cells can be induced. Base on the same direction synergic interaction between the changes of intracellular and extracellular acidity in tumor, the method may be achieved by injecting acid directly into tumor cells, or aggravating the anaerobic respiration of cancer cells through hyperthermia and other ways to enhance overall acidity in tumor tissues. The method may effectively induce mass apoptosis of cancer cells with little damaging to the normal cells, so as to inhibit the differentiation and proliferation of cancer cells, stop the metastasis and diffusion, and realize the radical cure of tumor.

Abstract: A global irradiation thermotherapy system based on coordinated rotation of microwave and radio frequency, including an annular phantom, an intelligent control unit, a microwave rotary heating mechanism, a capacitive radio frequency rotary heating mechanism and a temperature-measuring mechanism connected with the intelligent control unit. This disclosure also provides a global thermotherapy instrument.