Patents by Inventor Shengming Huang

Shengming Huang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8835424
    Abstract: In preferred embodiments, the present invention provides methods of treatment and pharmaceutical compositions for the suppression, alleviation and prevention of the often chronic, severe and debilitating pain that can accompany inflammatory diseases and neuropathic insults, pain that is often unresponsive to conventional analgesic treatment. The preferred embodiments of the present invention further relate to methods of treatment and pharmaceutical compositions using benzodiazepine derivatives that provide suppression, alleviation and prevention of neuropathic pain, migraine-related pain and inflammatory pain with reduced sedative and ataxic side effects.
    Type: Grant
    Filed: May 13, 2010
    Date of Patent: September 16, 2014
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: James Cook, Shengming Huang, Rahul Edwankar, Ojas A. Namjoshi, Zhi-Jian Wang
  • Publication number: 20100317619
    Abstract: In preferred embodiments, the present invention provides methods of treatment and pharmaceutical compositions for the suppression, alleviation and prevention of the often chronic, severe and debilitating pain that can accompany inflammatory diseases and neuropathic insults, pain that is often unresponsive to conventional analgesic treatment. The preferred embodiments of the present invention further relate to methods of treatment and pharmaceutical compositions using benzodiazepine derivatives that provide suppression, alleviation and prevention of neuropathic pain, migraine-related pain and inflammatory pain with reduced sedative and ataxic side effects.
    Type: Application
    Filed: May 13, 2010
    Publication date: December 16, 2010
    Inventors: James Cook, Shengming Huang, Rahul Edwankar, Ojas A. Namjoshi, Zhi-Jian Wang
  • Publication number: 20100261711
    Abstract: In preferred embodiments, the present invention provides methods of treatment and pharmaceutical compositions for the suppression, alleviation and prevention of seizures. The preferred embodiments of the present invention further relate to methods of treatment and pharmaceutical compositions using benzodiazepine derivatives that provide suppression, alleviation and prevention of seizures with reduced sedative and ataxic side effects.
    Type: Application
    Filed: March 17, 2010
    Publication date: October 14, 2010
    Applicant: WiSys Technology Foundation
    Inventors: James M. Cook, Rahul V. Edwankar, Chitra R. Edwankar, Shengming Huang, Hiteshkumar D. Jain, Jie Yang, Felix Rivas, Hao Zhou
  • Publication number: 20100004226
    Abstract: The present invention provides compositions and methods of using stereospecific benzodiazepine derivatives, their salts and prodrugs for the treatment of anxiolytic or convulsant disorders having the side effects of reduced alcohol craving in human alcoholics and a concomitant reduced sedative, hypnotic, muscle relaxant and ataxic side-effects. The invention further provides pharmaceutical compositions for treatment of anxiolytic and convulsant disorders in subjects in need thereof, comprising a compound, prodrug or a salt having a chemical structure represented by any one of Formula I-IV, VI-XI, XV-XVIII and XX-XXI and a pharmaceutically-acceptable carrier.
    Type: Application
    Filed: August 7, 2009
    Publication date: January 7, 2010
    Inventors: James M. Cook, Hao Zhou, Shengming Huang, P.V.V.S. Sarma, Chunchun Zhang
  • Patent number: 7618958
    Abstract: The present invention provides compositions and methods of using stereospecific benzodiazepine derivatives, their salts and prodrugs for the treatment of anxiolytic or convulsant disorders having the side effects of reduced alcohol craving in human alcoholics and a concomitant reduced sedative, hypnotic, muscle relaxant and ataxic side-effects. The invention further provides pharmaceutical compositions for treatment of anxiolytic and convulsant disorders in subjects in need thereof, comprising a compound, prodrug or a salt having a chemical structure represented by any one of Formula I-XXI and a pharmaceutically-acceptable carrier.
    Type: Grant
    Filed: June 30, 2005
    Date of Patent: November 17, 2009
    Assignee: WISYS Technology Foundation, Inc.
    Inventors: James M. Cook, Hao Zhou, Shengming Huang, P.V.V. Srirama Sarma, Chunchun Zhang
  • Patent number: 7619864
    Abstract: A signal source generates a reference voltage, and a voltage regulator receives the reference voltage and generates an output voltage and current. During normal operation, a pass element in the voltage regulator generates the output voltage, and a sense element generates a sense voltage. A first voltage detector detects a short-circuit condition using the sense voltage. A second voltage detector deactivates the pass element in response to the detection of the short-circuit condition. The second voltage detector also detects removal of the short-circuit condition and automatically reactivates the pass element. The first voltage detector may detect the short-circuit condition by detecting a drop in the sense voltage. The second voltage detector may detect the removal of the short-circuit condition by applying a test current to a load. Both the first and second voltage sensors may not consume any direct current power during normal operation of the voltage regulator.
    Type: Grant
    Filed: April 4, 2007
    Date of Patent: November 17, 2009
    Assignee: National Semiconductor Corporation
    Inventor: Shengming Huang
  • Patent number: 7402984
    Abstract: An oscillation sensor for a regulator that provides dynamic control of a connection/disconnection of a compensation capacitance. The compensation capacitor is disconnected under normal operation and is automatically connected if oscillation is detected in the output and regulator's error amplifier. In this way, oscillations are stopped in the regulator almost immediately after it occurs. Also, once the circuit is stable again, the compensation capacitor is quickly disconnected again. Consequently, the compensation capacitor does not adversely affect the overall performance of the regulator.
    Type: Grant
    Filed: March 9, 2005
    Date of Patent: July 22, 2008
    Assignee: National Semiconductor Corporation
    Inventor: Shengming Huang
  • Patent number: 7362081
    Abstract: A low-dropout regulator is provided that includes a filter and a bandgap reference generator. The filter includes a resistive device and a capacitor. The bandgap reference generator is coupled to the filter and includes a resistive device controller. The resistive device controller is operable to control the resistive device in the filter. The bandgap reference circuit is operable to generate an unfiltered voltage reference, and the filter is operable to generate a filtered voltage reference based on the unfiltered voltage reference.
    Type: Grant
    Filed: February 2, 2005
    Date of Patent: April 22, 2008
    Assignee: National Semiconductor Corporation
    Inventor: Shengming Huang
  • Patent number: 7312598
    Abstract: A low drop out (LDO) regulator that includes a novel error amplifier, which is arranged with a first stage that employs both NMOS and PMOS devices that are similarly doped in differential pairs and a second stage that operates with NMOS and PMOS devices in a push-pull arrangement. In addition to the error amplifier, the LDO regulator can also include a startup circuit coupled to an enable voltage, a reference filter circuit coupled to a reference voltage, an output circuit, a quiescent current control circuit, and a pulse generator circuit. Also, an internal RC network is provided to compensate for phase shift. The integrated operation of the components of the regulator enables stable and fast operation of an LDO regulator with no external capacitors connected to the input or output terminals.
    Type: Grant
    Filed: August 25, 2006
    Date of Patent: December 25, 2007
    Assignee: National Semiconductor Corporation
    Inventor: Shengming Huang
  • Patent number: 7129686
    Abstract: A tail current source is provided. The tail current source may be used in amplifiers, in an error amplifier of an LDO, or the like, to achieve high PSRR. The tail current source includes a first current mirror, a capacitor, a resistive device, and a current mirror circuit. The current mirror circuit is operable to provide the tail current from an input current. The first current mirror is an n-type current mirror which diverts a small fraction of the DC current from the current mirror circuit. The capacitor and the resistive device are coupled in series with each other, and are coupled between VDD and the common gate node of the transistors in the n-type current mirror. Accordingly, the gates of the transistors in the first current mirror follow AC variations in VDD. This way, the effects of AC variations in VDD on the tail current are approximately cancelled.
    Type: Grant
    Filed: August 3, 2005
    Date of Patent: October 31, 2006
    Assignee: National Semiconductor Corporation
    Inventor: Shengming Huang
  • Patent number: 7122996
    Abstract: A voltage regulator circuit is arranged to provide a regulated output voltage from an unregulated input voltage. Also, the voltage regulator circuit includes a capacitor that is coupled between output and feedback nodes of the voltage regulator circuit. The capacitor may improve transient responses, output noise, and the power supply rejection ratio of the voltage regulator circuit during normal operation. During a start-up of the voltage regulator circuit, the capacitance between the output and feedback nodes is substantially eliminated or substantially reduced in order to reduce the time that it takes for the output voltage to reach a stable voltage level.
    Type: Grant
    Filed: June 1, 2004
    Date of Patent: October 17, 2006
    Assignee: National Semiconductor Corporation
    Inventor: Shengming Huang
  • Patent number: 7042280
    Abstract: A regulator system includes a power device and a sense device. During a normal operating mode, the power device is arranged to deliver current to a load, while the sense device is arranged to monitor the load current. An over-current mode is activated when the sensed load current exceeds a short-circuit current-limit. During the over-current mode, the power device is switched off such that the energy loss is minimized. Once the short-circuit condition is removed, the regulator system returns to the normal operating mode. The sense device is coupled to the load in such a way that the quiescent current of the regulator system does not rise with increasing load current. The regulator system is further arranged such that the short-circuit current-limit decreases automatically with increased operating temperature. The described regulator system has significantly reduced energy losses while also minimizing risks of thermal induced device failures during the short-circuit condition.
    Type: Grant
    Filed: December 15, 2003
    Date of Patent: May 9, 2006
    Assignee: National Semiconductor Corporation
    Inventors: Shengming Huang, Robin Shields, John Gough
  • Publication number: 20060003995
    Abstract: The present invention provides compositions and methods of using stereospecific benzodiazepine derivatives, their salts and prodrugs for the treatment of anxiolytic or convulsant disorders having the side effects of reduced alcohol craving in human alcoholics and a concomitant reduced sedative, hypnotic, muscle relaxant and ataxic side-effects. The invention further provides pharmaceutical compositions for treatment of anxiolytic and convulsant disorders in subjects in need thereof, comprising a compound, prodrug or a salt having a chemical structure represented by any one of Formula I-XXI and a pharmaceutically-acceptable carrier.
    Type: Application
    Filed: June 30, 2005
    Publication date: January 5, 2006
    Applicant: WISYS TECHNOLOGY FOUNDATION, INC.
    Inventors: James Cook, Hao Zhou, Shengming Huang, P.V.V.S Sarma, Chunchun Zhang
  • Patent number: 6859077
    Abstract: A startup circuit is used for producing a startup current for an analog integrated circuit device. The startup circuit includes a first portion including a diode component and a capacitance component. The first portion is configured to function as a power supply backup and generate a backup point voltage. The startup circuit includes a second portion including a current mirror component and a feedback component. The second portion is configured to generate a startup current using the backup point voltage, such that the startup current is provided based on the backup point voltage as a power supply voltage increases from a power off condition or a transient, thereby keeping an analog circuit alive during transients in power supply for fast recover and operation.
    Type: Grant
    Filed: August 25, 2003
    Date of Patent: February 22, 2005
    Assignee: National Semiconductor Corporation
    Inventors: Shengming Huang, Andre Schouten
  • Patent number: RE47475
    Abstract: In preferred embodiments, the present invention provides methods of treatment and pharmaceutical compositions for the suppression, alleviation and prevention of the often chronic, severe and debilitating pain that can accompany inflammatory diseases and neuropathic insults, pain that is often unresponsive to conventional analgesic treatment. The preferred embodiments of the present invention further relate to methods of treatment and pharmaceutical compositions using benzodiazepine derivatives that provide suppression, alleviation and prevention of neuropathic pain, migraine-related pain and inflammatory pain with reduced sedative and ataxic side effects.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: July 2, 2019
    Assignee: WISYS TECHNOLOGY FOUNDATION, INC.
    Inventors: James M. Cook, Shengming Huang, Rahul Edwankar, Ojas A. Namjoshi, Zhi-Jian Wang, Qi Huang, Xiaohui He, Xiaoyan Li, Jianming Yu, Dongmei Han