Patents by Inventor Shengqiang Gao
Shengqiang Gao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11957351Abstract: Tissue ligation systems and methods are provides to mechanically strangulate abnormal or undesirable tissue. Tissue ligation systems include a multi-lumen catheter having an outer diameter smaller than the inner diameter of a standard endoscope channel such that the catheter can be inserted into the endoscope. Tissue ligation systems also include a ligation apparatus with an expandable hood disposed at the distal end of the catheter. A suture extends through a lumen of the catheter and has a distal loop portion that can strangulate tissue.Type: GrantFiled: November 9, 2021Date of Patent: April 16, 2024Assignee: THE CLEVELAND CLINIC FOUNDATIONInventors: Nizar Zein, Shengqiang Gao
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Publication number: 20230017864Abstract: Systems and methods for sonicating a body within an organ of a patient include supplying ultrasound energy to the body in order to produce a liquified material, which can then be aspirated from the body via a catheter. Image guidance is used during aspiration of the liquified material.Type: ApplicationFiled: July 19, 2022Publication date: January 19, 2023Inventors: Sean J. Nagel, Mark D. Bain, Stephen Jones, Shengqiang Gao
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Publication number: 20220354475Abstract: Systems, methods, and apparatuses for assisting with submucosal dissections include a retraction strip body. The retraction strip body is formed at least partially from a deformable material. The retraction strip body is capable of being selectively moved between a first condition and a second condition. In the first condition, the retraction strip body is capable of engaging a target patient tissue. In the second condition, the retraction strip body is capable of retracting the target patient tissue. At least one tissue engagement member is located on the retraction strip body.Type: ApplicationFiled: July 27, 2022Publication date: November 10, 2022Inventors: Amit Bhatt, Shengqiang Gao, William Kolosi, John Vargo
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Publication number: 20220354564Abstract: An endoscopic instrument containing a retractable tool at its end that is articulated by engaging an actuator that moves pull wires to angularly move the tip of the instrument along a plane for conducting a procedure at a target site. The tool of instrument is linearly move from an extension position to a retracted position by another actuator. The instrument provide rotational control of the tool and instrument tip portion with a rotational actuator for rotating housings that carry both pull wires and a conducting wire connected to the tool.Type: ApplicationFiled: May 6, 2022Publication date: November 10, 2022Inventors: Tolga Erim, Tanju Erim, Shengqiang Gao
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Publication number: 20220142648Abstract: Tissue ligation systems and methods are provides to mechanically strangulate abnormal or undesirable tissue. Tissue ligation systems include a multi-lumen catheter having an outer diameter smaller than the inner diameter of a standard endoscope channel such that the catheter can be inserted into the endoscope. Tissue ligation systems also include a ligation apparatus with an expandable hood disposed at the distal end of the catheter. A suture extends through a lumen of the catheter and has a distal loop portion that can strangulate tissue.Type: ApplicationFiled: November 9, 2021Publication date: May 12, 2022Inventors: Nizar Zein, Shengqiang Gao
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Patent number: 11324511Abstract: Tissue ligation devices and methods are provides to mechanically strangulate abnormal or undesirable tissue. Tissue ligation devices include a catheter having an outer diameter smaller than the inner diameter of a standard endoscope channel such that the catheter can be inserted into the endoscope. Tissue ligation devices also include a ligation system with an expandable hood disposed located at the distal end of the catheter. A suture extends through a lumen of the catheter and has a distal loop portion exposed outside of the expandable hood.Type: GrantFiled: April 13, 2018Date of Patent: May 10, 2022Assignee: THE CLEVELAND CLINIC FOUNDATIONInventors: Nizar Zein, Shengqiang Gao
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Publication number: 20220133202Abstract: ECG electrode assemblies are disclosed which include an adhesive-backed patch incorporating an ECG electrode and an adhesive-backed cover configured to cover and surround a lead wire clip attached to a contact of the ECG electrode. ECG electrode assemblies comprising said adhesive-backed patch and said adhesive-backed cover secure the connection between the lead and the electrode and effectively reduce the number of telemetry disruptions due to leads failure. ECG electrode assemblies can also provide water resistance to allow for patient showering while hospitalized on telemetry monitoring.Type: ApplicationFiled: October 26, 2021Publication date: May 5, 2022Inventors: Daniel Cantillon, Marc Petre, Shengqiang Gao, Torey Hovest
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Patent number: 10939999Abstract: An apparatus for replacing a diseased cardiac valve is movable from a radially collapsed configuration to a radially expanded configuration. The apparatus comprises an expandable support member and a prosthetic valve secured therein. The main body portion extends between first and second end portions and includes an outer circumferential surface, a circumferential axis extending about the circumferential surface, and a plurality of wing members spaced apart from one another by an expandable region. Each of the wing members includes first and second end portions and a flexible middle portion extending between the end portions. The second end portion is integrally formed with the uyimain body portion. The first end portion is adjacent the circumferential axis and substantially flush with the outer circumferential surface in the radially collapsed configuration. The first end portion extends substantially radial to the outer circumferential surface in the radially expanded configuration.Type: GrantFiled: July 2, 2018Date of Patent: March 9, 2021Assignee: THE CLEVELAND CLINIC FOUNDATIONInventors: Jose L. Navia, Ji-Feng Chen, Shengqiang Gao, Brian L. Davis, Samantha Stucke
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Patent number: 10850079Abstract: A system is provided for healing a wound. The system includes a flexible body, a therapeutic agent delivery mechanism, a suction mechanism, and a power source. The flexible body includes a cover film having oppositely disposed first and second surfaces that define a compartment. The compartment includes a first porous material, a second porous material, and at least one electrode disposed therein. The second porous material is disposed between the first porous material and the at least one electrode. The therapeutic agent delivery mechanism and the suction mechanism are fluidly connected to the compartment. The power source is in electrical communication with the at least one electrode.Type: GrantFiled: June 7, 2018Date of Patent: December 1, 2020Assignee: THE CLEVELAND CLINIC FOUNDATIONInventors: Francis A. Papay, Ji-Feng Chen, Shengqiang Gao
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Publication number: 20200093633Abstract: Stoma site protection devices, kits, assemblies and methods are provided that prevent or minimize leakage from a stoma. A stoma site protection device includes a conformal plug that can adapt to the stoma track. Kits and assemblies include additional components such as flexible external bumpers and bandages that provide multiple sealing of the stoma.Type: ApplicationFiled: August 22, 2019Publication date: March 26, 2020Inventors: Eric Yudelevich Blumrosen, Andrew G. Williams, Shengqiang Gao
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Patent number: 10335609Abstract: A system for delivery of radiation to a target portion of a native tissue is provided. The system includes a catheter having a catheter body with a proximal portion, a distal portion, and a longitudinally oriented lumen therebetween. The system further includes an expansion device disposed about at least a portion of the catheter body and having an expanded configuration and a non-expanded configuration. The system also includes a plurality of tubes disposed about at least a portion of the expansion device. Each of the plurality of tubes is configured to selectively guide exposure of a radiation source to the target portion of the native tissue.Type: GrantFiled: September 8, 2015Date of Patent: July 2, 2019Assignee: THE CLEVELAND CLINIC FOUNDATIONInventors: John Greskovich, Jr., Shengqiang Gao
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Publication number: 20190175163Abstract: Systems, methods, and apparatuses for assisting with submucosal dissections include a retraction strip body. The retraction strip body is formed at least partially from a deformable material. The retraction strip body is capable of being selectively moved between a first condition and a second condition. In the first condition, the retraction strip body is capable of engaging a target patient tissue. In the second condition, the retraction strip body is capable of retracting the target patient tissue. At least one tissue engagement member is located on the retraction strip body.Type: ApplicationFiled: February 19, 2019Publication date: June 13, 2019Inventors: Amit Bhatt, Shengqiang Gao, William Kolosi, John Vargo
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Patent number: 10206669Abstract: Systems, methods, and apparatuses for assisting with submucosal dissections include a retraction strip body. The retraction strip body is formed at least partially from a deformable material. The retraction strip body is capable of being selectively moved between a first condition and a second condition. In the first condition, the retraction strip body is capable of engaging a target patient tissue. In the second condition, the retraction strip body is capable of retracting the target patient tissue. At least one tissue engagement member is located on the retraction strip body.Type: GrantFiled: January 19, 2017Date of Patent: February 19, 2019Assignee: THE CLEVELAND CLINIC FOUNDATIONInventors: Amit Bhatt, Shengqiang Gao, William Kolosi, John Vargo
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Publication number: 20190008632Abstract: An apparatus for replacing a diseased cardiac valve is movable from a radially collapsed configuration to a radially expanded configuration. The apparatus comprises an expandable support member and a prosthetic valve secured therein. The main body portion extends between first and second end portions and includes an outer circumferential surface, a circumferential axis extending about the circumferential surface, and a plurality of wing members spaced apart from one another by an expandable region. Each of the wing members includes first and second end portions and a flexible middle portion extending between the end portions. The second end portion is integrally formed with the uyimain body portion. The first end portion is adjacent the circumferential axis and substantially flush with the outer circumferential surface in the radially collapsed configuration. The first end portion extends substantially radial to the outer circumferential surface in the radially expanded configuration.Type: ApplicationFiled: July 2, 2018Publication date: January 10, 2019Applicant: THE CLEVELAND CLINIC FOUNDATIONInventors: Jose L. Navia, Ji-Feng Chen, Shengqiang Gao, Brian L. Davis, Samantha Stucke
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Publication number: 20180296220Abstract: Tissue ligation devices and methods are provides to mechanically strangulate abnormal or undesirable tissue. Tissue ligation devices include a catheter having an outer diameter smaller than the inner diameter of a standard endoscope channel such that the catheter can be inserted into the endoscope. Tissue ligation devices also include a ligation system with an expandable hood disposed located at the distal end of the catheter. A suture extends through a lumen of the catheter and has a distal loop portion exposed outside of the expandable hood.Type: ApplicationFiled: April 13, 2018Publication date: October 18, 2018Inventors: Nizar Zein, Shengqiang Gao
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Publication number: 20180289936Abstract: A system is provided for healing a wound. The system includes a flexible body, a therapeutic agent delivery mechanism, a suction mechanism, and a power source. The flexible body includes a cover film having oppositely disposed first and second surfaces that define a compartment. The compartment includes a first porous material, a second porous material, and at least one electrode disposed therein. The second porous material is disposed between the first porous material and the at least one electrode. The therapeutic agent delivery mechanism and the suction mechanism are fluidly connected to the compartment. The power source is in electrical communication with the at least one electrode.Type: ApplicationFiled: June 7, 2018Publication date: October 11, 2018Inventors: Francis A. Papay, Ji-Feng Chen, Shengqiang Gao
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Patent number: 10028704Abstract: A guidewire (10) includes a flexible elongated core (20) having a proximal end (22) and a distal end (24). An anchor wire (10) has a distal end (34) connected to the distal end (24) of the core (20) and a distally located helical portion (50) that encircles the core. The guidewire (10) has an anchoring condition in which the helical portion (50) is expanded radially away from the core (20). The guidewire (10) has an advancing condition in which the helical portion (50) is stretched longitudinally and contracted radially in response to tension on the anchor wire (30).Type: GrantFiled: March 7, 2014Date of Patent: July 24, 2018Assignee: The Cleveland Clinic FoundationInventors: Ferdinand Hui, Shengqiang Gao
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Patent number: 10010416Abstract: An apparatus for replacing a diseased cardiac valve is movable from a radially collapsed configuration to a radially expanded configuration. The apparatus comprises an expandable support member and a prosthetic valve secured therein. The main body portion extends between first and second end portions and includes an outer circumferential surface, a circumferential axis extending about the circumferential surface, and a plurality of wing members spaced apart from one another by an expandable region. Each of the wing members includes first and second end portions and a flexible middle portion extending between the end portions. The second end portion is integrally formed with the uyimain body portion. The first end portion is adjacent the circumferential axis and substantially flush with the outer circumferential surface in the radially collapsed configuration. The first end portion extends substantially radial to the outer circumferential surface in the radially expanded configuration.Type: GrantFiled: March 31, 2014Date of Patent: July 3, 2018Assignee: THE CLEVELAND CLINIC FOUNDATIONInventors: Jose L. Navia, Ji-Feng Chen, Shengqiang Gao, Brian L. Davis, Samantha Stucke
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Patent number: 10004881Abstract: A system is provided for healing a wound. The system includes a flexible body, a therapeutic agent delivery mechanism, a suction mechanism, and a power source. The flexible body includes a cover film having oppositely disposed first and second surfaces that define a compartment. The compartment includes a first porous material, a second porous material, and at least one electrode disposed therein. The second porous material is disposed between the first porous material and the at least one electrode. The therapeutic agent delivery mechanism and the suction mechanism are fluidly connected to the compartment. The power source is in electrical communication with the at least one electrode.Type: GrantFiled: October 13, 2016Date of Patent: June 26, 2018Assignee: THE CLEVELAND CLINIC FOUNDATIONInventors: Francis A. Papay, Ji-Feng Chen, Shengqiang Gao
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Patent number: 9968765Abstract: A convection enhanced delivery device comprises a support member and an elongated microcatheter carried by the support member. The microcatheter projects lengthwise away from the support member. The microcatheter includes a catheter lumen extending in a first direction. A fluid conduit carried by the support member. The fluid conduit includes a conduit lumen that extends in a second direction different than the first direction. The conduit lumen is in fluid communication with the catheter lumen. An inlet port and a connecting port are also carried by the support member. The inlet port is in fluid communication with the fluid conduit. The connecting port is separate from the inlet port and is in fluid communication with the fluid conduit. The connecting port is configured to engage an end portion of an external fluid conduit such that the external fluid conduit projects away from the connecting port and from the support member.Type: GrantFiled: January 21, 2016Date of Patent: May 15, 2018Assignee: The Cleveland Clinic FoundationInventors: Michael A. Vogelbaum, Shengqiang Gao, William Kolosi