Patents by Inventor Shenyi Shi

Shenyi Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymorphs of Crystalline Forms of 3,10-dimethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinolin-9-yl 3-fluorobenzenesulfonate and Salts Thereof
    Publication number: 20230279002
    Abstract: Crystalline salts of compounds, methods of making the same, and methods of treatment of dyslipidemia including administration of the crystalline salts, are provided.
    Type: Application
    Filed: March 1, 2023
    Publication date: September 7, 2023
    Applicant: CVI Pharmaceuticals Limited
    Inventors: Shenyi Shi, Feng Wang, Jingwen Liu, Jian Yang
  • Crystal form and salt form of TGF-?RI inhibitor and preparation method therefor
    Patent number: 11236112
    Abstract: Disclosed in the present invention are a crystal form and salt form of a TGF-?R1 inhibitor and a preparation method therefor, and further disclosed is an application of the crystal form and the salt form in preparation of medicines for treating cancers.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: February 1, 2022
    Assignee: GENFLEET THERAPEUTICS (SHANGHAI) INC.
    Inventors: Lifang Wu, Huijun He, Jianyu Lu, Charles Z. Ding, Lihong Hu, Weidong Li, Shenyi Shi, Jian Li, Shuhui Chen
  • Crystal Form of Hepatitis B Surface Antigen Inhibitor
    Publication number: 20220017536
    Abstract: The present invention discloses a crystal form of a hepatitis B surface antigen inhibitor and a preparation method therefor, and also comprises the use of the crystal form in preparing the hepatitis B surface antigen inhibitor.
    Type: Application
    Filed: November 22, 2019
    Publication date: January 20, 2022
    Inventors: Yanbin HU, Fei SUN, Shenyi SHI, Yanxiao SU, Charles Z DING
  • Salt Form of Estrogen Receptor Downregulator, Crystalline Form Thereof, and Preparation Method Therefor
    Publication number: 20220017463
    Abstract: Provided are a salt form of an estrogen receptor down-regulator, a crystalline form thereof, and a preparation method therefor.
    Type: Application
    Filed: October 17, 2019
    Publication date: January 20, 2022
    Inventors: Huijun HE, Shenyi SHI, Jianyu LU, Charles Z. DING, Lihong HU, Bin SHI, Wenqian YANG, Jiaqiang DONG, Tie-Lin WANG
  • Salts and crystal forms of diaza-benzofluoranthrene compounds
    Patent number: 11124506
    Abstract: The present invention discloses to a hydrochloride salt, a citrate salt, a phosphate salt or a sulfate salt of compound 1, the crystal forms of the aforementioned salts, and a preparation method thereof. The present invention also relates their use in the preparation of a medicament for the treatment of cerebral apoplexy or epilepsy.
    Type: Grant
    Filed: August 3, 2017
    Date of Patent: September 21, 2021
    Assignee: HARBIN PHARMACEUTICAL GROUP CO., LTD. GENERAL PHARMACEUTICAL FACTORY
    Inventors: Qingqing Lu, Shenyi Shi, Tiezhong Bai, Shujie Yuan, Zhengwu Li, Qiaofen Hu, Yijie Cao, Jing Gao, Hui Ding, Jinhua Li, Guanghai Xu, Zheng Wang, Xin Jin
  • Crystal form of estrogen receptor inhibitor and preparation method therefor
    Patent number: 11034653
    Abstract: Disclosed are a crystal form of an estrogen receptor inhibitor and a preparation method therefor, in particular disclosed are a crystal form A of a compound of formula (I) and a preparation method therefor, and the use of the crystal form in the preparation of a drug for treating breast cancer.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: June 15, 2021
    Assignees: LUOXIN PHARMACEUTICAL (SHANGHAI) CO., LTD., SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.
    Inventors: Huijun He, Jianyu Lu, Weidong Li, Shenyi Shi, Zhijuan Chen, Charles Z. Ding, Lihong Hu, Tie-Lin Wang, Jiaqiang Dong
  • CRYSTAL FORM AND SALT FORM OF TGF-BRI INHIBITOR AND PREPARATION METHOD THEREFOR
    Publication number: 20210079021
    Abstract: Disclosed in the present invention are a crystal form and salt form of a TGF-?R1 inhibitor and a preparation method therefor, and further disclosed is an application of the crystal form and the salt form in preparation of medicines for treating cancers.
    Type: Application
    Filed: December 13, 2018
    Publication date: March 18, 2021
    Inventors: Lifang WU, Huijun HE, Jianyu LU, Charles Z. DING, Lihong HU, Weidong LI, Shenyi SHI, Jian LI, Shuhui CHEN
  • CRYSTAL FORM OF ESTROGEN RECEPTOR INHIBITOR AND PREPARATION METHOD THEREFOR
    Publication number: 20200247748
    Abstract: Disclosed are a crystal form of an estrogen receptor inhibitor and a preparation method therefor, in particular disclosed are a crystal form A of a compound of formula (I) and a preparation method therefor, and the use of the crystal form in the preparation of a drug for treating breast cancer.
    Type: Application
    Filed: September 25, 2018
    Publication date: August 6, 2020
    Inventors: Huijun HE, Jianyu LU, Weidong LI, Shenyi SHI, Zhijuan CHEN, Charles Z. DING, Lihong HU, Tie-Lin WANG, Jiaqiang DONG
  • SALTS AND CRYSTAL FORMS OF DIAZA-BENZOFLUORANTHRENE COMPOUNDS
    Publication number: 20190169183
    Abstract: The present invention discloses to a hydrochloride salt, a citrate salt, a phosphate salt or a sulfate salt of compound 1, the crystal forms of the aforementioned salts, and a preparation method thereof. The present invention also relates their use in the preparation of a medicament for the treatment of cerebral apoplexy or epilepsy.
    Type: Application
    Filed: August 3, 2017
    Publication date: June 6, 2019
    Inventors: Qingqing Lu, Shenyi Shi, Tiezhong Bai, Shujie Yuan, Zhengwu Li, Qiaofen Hu, Yijie Cao, Jing Gao, Hui Ding, Jinhua Li, Guanghai Xu, Zheng Wang, Xin Jin