Patents by Inventor Sherin S Abdel-Meguid

Sherin S Abdel-Meguid has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds and Methods For Treatment of Thrombosis
    Publication number: 20080146811
    Abstract: The invention provides compounds, pharmaceutical compositions, and methods for the treatment of thromboembolic disorders, such as, for example, arterial cardiovascular thromboembolic disorders, venous cardiovascular thromboembolic disorders, or thromboembolic disorders in the chambers of the heart.
    Type: Application
    Filed: July 22, 2005
    Publication date: June 19, 2008
    Inventors: Hongfeng Deng, Jian Lin, Zihong Guo, Harold V. Meyers, Sherin S. Abdel-Meguid, Robert E. Babine
  • Compounds and methods for treatment of thrombosis
    Patent number: 7217794
    Abstract: The present invention provides compounds that inhibit Factor XIa and methods of preventing or treating undesired thrombosis by administering a compound of the invention to a mammal. The invention also provides three-dimensional structures of Factor XIa and methods for designing or selecting additional Factor XIa inhibitors using these structures.
    Type: Grant
    Filed: April 2, 2004
    Date of Patent: May 15, 2007
    Assignee: Daiamed, Inc.
    Inventors: Sherin S. Abdel-Meguid, Robert E. Babine, Hongfeng Deng, Lei Jin, Jian Lin, Scott R. Magee, Harold V. Meyers, Pramod Pandey, Michael J. Rynkiewicz, David T. Weaver, Zihong Gho, Thomas D. Bannister
  • Recombinant IL-18 antagonists useful in treatment of IL-18 mediated disorders
    Publication number: 20040141964
    Abstract: Chimeric, humanized and other IL-18 mAbs, derived from high affinity neutralizing mAbs, pharmaceutical compositions containing same, methods of treatment and diagnostics are provided.
    Type: Application
    Filed: January 22, 2004
    Publication date: July 22, 2004
    Applicant: SmithKline Beecham Corporation and SmithKline Beecham p.l.c.
    Inventors: Sherin S. Abdel-Meguid, Yen Sen Ho, Stephen D. Holmes, Alexander H. Taylor
  • Monoclonal antibody and the method of using the antibody
    Patent number: 6706487
    Abstract: Chimeric, humanized and other IL-18 mAbs, derived from high affinity neutralizing mAbs, pharmaceutical compositions containing same, methods of treatment and diagnostics are provided.
    Type: Grant
    Filed: August 31, 2001
    Date of Patent: March 16, 2004
    Assignee: SmithKline Beecham Corporation
    Inventors: Sherin S. Abdel-Meguid, Yen Sen Ho, Stephen D. Holmes, Alexander H. Taylor
  • Cytokine family member, 2-19
    Publication number: 20010049121
    Abstract: 2-19 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing 2-19 polypeptides and polynucleotides in therapy, and diagnostic assays for such.
    Type: Application
    Filed: January 12, 2001
    Publication date: December 6, 2001
    Inventors: Sherin S. Abdel-Meguid, Rajeev Aurora, Preston Hensley, George D. Rose, Peter R. Young, Yuan Zhu
  • Cytokine family member EF-7
    Patent number: 6245550
    Abstract: EF-7 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing EF-7 polypeptides and polynucleotides in therapy, and diagnostic assays for such.
    Type: Grant
    Filed: March 20, 1998
    Date of Patent: June 12, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Sherin S Abdel-Meguid, Rajeev Aurora, Derk J Bergsma, Catherine E Ellis, Stephanie F Guerrera, Preston Hensley, Jeffrey L Mooney, George D Rose, Peter R Young, Yuan Zhu