Patents by Inventor Sherrol H. McDonough

Sherrol H. McDonough has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection of HIV-1 by nucleic acid amplification
    Patent number: 7723040
    Abstract: Nucleic acid sequences and methods for detecting HIV-1 nucleic acid (LTR and pol sequences) in biological samples by detecting amplified nucleic acids are disclosed. Kits comprising nucleic acid oligomers for amplifying HIV-1 nucleic acid present in a biological sample and detecting the amplified nucleic acid are disclosed.
    Type: Grant
    Filed: September 4, 2008
    Date of Patent: May 25, 2010
    Assignee: Gen-Probe Incorporated
    Inventors: Gary G. Bee, Yeasing Y. Yang, Dan Kolk, Cristina Giachetti, Sherrol H. McDonough
  • DETECTION OF HIV-1 BY NUCLEIC ACID AMPLIFICATION
    Publication number: 20090053692
    Abstract: Nucleic acid sequences and methods for detecting HIV-1 nucleic acid (LTR and pol sequences) in biological samples by detecting amplified nucleic acids are disclosed. Kits comprising nucleic acid oligomers for amplifying HIV-1 nucleic acid present in a biological sample and detecting the amplified nucleic acid are disclosed.
    Type: Application
    Filed: September 4, 2008
    Publication date: February 26, 2009
    Inventors: Gary G. BEE, Yeasing Y. Yang, Dan Kolk, Cristina Giahetti, Sherrol H. McDonough
  • Detection of HIV-1 by nucleic acid amplification
    Patent number: 7425417
    Abstract: Nucleic acid sequences and methods for detecting HIV-1 nucleic acid (LTR and pol sequences) in biological samples by detecting amplified nucleic acids are disclosed. Kits comprising nucleic acid oligomers for amplifying HIV-1 nucleic acid present in a biological sample and detecting the amplified nucleic acid are disclosed.
    Type: Grant
    Filed: July 24, 2006
    Date of Patent: September 16, 2008
    Assignee: Gen-Probe Incorporated
    Inventors: Gary G. Bee, Yeasing Y. Yang, Dan Kolk, Cristina Giachetti, Sherrol H. McDonough
  • Detection of HIV-1 by nucleic acid amplification
    Patent number: 7097979
    Abstract: Nucleic acid sequences and methods for detecting HIV-1 nucleic acid (LTR and pol sequences) in biological samples by detecting amplified nucleic acids are disclosed. Kits comprising nucleic acid oligomers for amplifying HIV-1 nucleic acid present in a biological sample and detecting the amplified nucleic acid are disclosed.
    Type: Grant
    Filed: August 1, 2003
    Date of Patent: August 29, 2006
    Assignee: Gen-Probe Incorporated
    Inventors: Gary G. Bee, Yeasing Y. Yang, Dan Kolk, Cristina Giachetti, Sherrol H. McDonough
  • Detection of HIV
    Patent number: 7083922
    Abstract: The present invention relates to oligonucleotides for use in amplifying and detecting HIV nucleic acid in a sample.
    Type: Grant
    Filed: September 16, 2002
    Date of Patent: August 1, 2006
    Assignee: Gen-Probe Incorporated
    Inventors: Daniel L. Kacian, Timothy J. Fultz, Sherrol H. McDonough
  • Oligonucleotides for nucleic acid amplification and for the detection of
    Patent number: 7009041
    Abstract: A method, composition and kit for synthesizing multiple copies of a target nucleic acid sequence autocatalytically under conditions of substantially constant temperature, ionic strength, and pH are provided in which multiple RNA copies of the target sequence autocatalytically generate additional copies using a mixture of blocked and unblocked primers and/or promoter-primers to initiate DNA and RNA synthesis, preferably with reduced non-specific product formation. The invention is useful for generating copies of a nucleic acid target sequence for purposes that include assays to quantitate specific nucleic acid sequences in clinical, environmental, forensic and similar samples, cloning and generating probes.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: March 7, 2006
    Assignee: Gen-Probe Incorporated
    Inventors: Sherrol H. McDonough, Daniel L. Kacian, Nanibhushan Dattagupta, Diane L. McAllister, Philip W. Hammond, Thomas B. Ryder
  • Detection of HIV-1 by nucleic acid amplification
    Publication number: 20040053223
    Abstract: Nucleic acid sequences and methods for detecting HIV-1 nucleic acid (LTR and pol sequences) in biological samples by detecting amplified nucleic acids are disclosed. Kits comprising nucleic acid oligomers for amplifying HIV-1 nucleic acid present in a biological sample and detecting the amplified nucleic acid are disclosed.
    Type: Application
    Filed: August 1, 2003
    Publication date: March 18, 2004
    Inventors: Gary G. Bee, Yeasing Y. Yang, Dan Kolk, Cristina Giachetti, Sherrol H. McDonough
  • Detection of human immunodeficiency virus type 1
    Patent number: 6649749
    Abstract: Amplification oligonucleotides and hybridization assay probes which distinguish Human Immunodeficiency Virus type 1 from other viruses.
    Type: Grant
    Filed: January 20, 2001
    Date of Patent: November 18, 2003
    Assignee: Gen-Probe Incorporated
    Inventors: Sherrol H. McDonough, Thomas B. Ryder, Yeasing Yang
  • Detection of HIV-1 by nucleic acid amplification
    Patent number: 6623920
    Abstract: Nucleic acid sequences and methods for detecting HIV-1 nucleic acid (LTR and pol sequences) in biological samples by detecting amplified nucleic acids are disclosed. Kits comprising nucleic acid oligomers for amplifying HIV-1 nucleic acid present in a biological sample and detecting the amplified nucleic acid are disclosed.
    Type: Grant
    Filed: July 7, 2000
    Date of Patent: September 23, 2003
    Assignee: Gen-Probe Incorporated
    Inventors: Gary G. Bee, Yeasing Y. Yang, Dan Kolk, Cristina Giachetti, Sherrol H. McDonough
  • Detection of HIV
    Publication number: 20030152916
    Abstract: The present invention relates to oligonucleotides for use in amplifying and detecting HIV nucleic acid in a sample.
    Type: Application
    Filed: September 16, 2002
    Publication date: August 14, 2003
    Inventors: Daniel L. Kacian, Timothy J. Fultz, Sherrol H. McDonough
  • Detection of HIV
    Patent number: 6589734
    Abstract: The present invention related to oligonucleotides for use in amplifying and detecting HIV nucleic acid in a sample.
    Type: Grant
    Filed: October 8, 1998
    Date of Patent: July 8, 2003
    Assignee: Gen-Probe Incorporated
    Inventors: Daniel L. Kacian, Timothy J. Fultz, Sherrol H. McDonough
  • Detection of Human Immunodeficiency Virus type 1
    Publication number: 20020062016
    Abstract: Amplification oligonucleotides and hybridization assay probes which distinguish Human Immunodeficiency Virus type 1 from other viruses.
    Type: Application
    Filed: January 20, 2001
    Publication date: May 23, 2002
    Applicant: Gen-Probe Incorporated
    Inventors: Sherrol H. McDonough, Thomas B. Ryder, Yeasing Yang
  • Detection of human immunodeficiency virus type 1
    Patent number: 6252059
    Abstract: Amplification oligonucleotides and hybridization assay probes which distinguish Human Immunodeficiency Virus type 1 from other viruses.
    Type: Grant
    Filed: January 26, 1998
    Date of Patent: June 26, 2001
    Assignee: Gen-Probe Incorporated
    Inventors: Sherrol H. McDonough, Thomas B. Ryder, Yeasing Yang
  • Protection probes
    Patent number: 6245519
    Abstract: The present invention features compositions and methods that are useful for storing labeled detection probes and detecting whether a target nucleic acid sequence is present in a sample. Preferred compositions are made up of a detection probe containing a label susceptible to a chemical or enzymatic alteration and a protection probe that protects the label from alteration and/or decreases the ability of the detection probe to inhibit nucleic acid amplification. Such compositions can be used, for example, to stabilize a detection probe label and to prevent a detection probe from hybridizing prematurely to amplified or target nucleic acid.
    Type: Grant
    Filed: February 11, 2000
    Date of Patent: June 12, 2001
    Assignee: Gen-Probe Incorporated
    Inventors: Steven T. Brentano, Sherrol H. McDonough, Norman C. Nelson
  • Oligonucleotide probes and methods for detecting Streptococcus pneumoniae
    Patent number: 5888729
    Abstract: A method, composition and kit for amplifying a target nucleic acid sequence under conditions of substantially constant temperature, ionic strength, and pH and using only a single promoter-primer. To effect the amplification, a supply of a single promoter-primer having a promoter and a primer complementary to the 3'-end of the target sequence, and a reverse transcriptase and an RNA polymerase are provided to a mixture including the target sequence; the amplification proceeds accordingly. The invention is useful for generating copies of a nucleic acid target sequence for purposes that include assays to quantitate specific nucleic acid sequences in clinical, environmental, forensic and similar samples, cloning and generating probes.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: March 30, 1999
    Assignee: Gen-Probe Incorporated
    Inventors: Daniel L. Kacian, Diane L. McAllister, Sherrol H. McDonough, Nanibhushan Dattagupta
  • Detection of human immunodeficiency virus type 1
    Patent number: 5856088
    Abstract: Amplification oligonucleotides and hybridization assay probes which distinguish Human Immunodeficiency Virus type from other viruses.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: January 5, 1999
    Assignee: Gen-Probe Incorporated
    Inventors: Sherrol H. McDonough, Thomas B. Ryder, Yeasing Yang
  • Nucleic acid amplification oligonucleotides and probes to human hepatitis B virus
    Patent number: 5780219
    Abstract: Amplification oligonucleotides and hybridization assay probes specific for Human Hepatitis B Virus.
    Type: Grant
    Filed: January 12, 1995
    Date of Patent: July 14, 1998
    Assignee: Gen-Probe Incorporated
    Inventors: Sherrol H. McDonough, Timothy J. Fultz
  • Methods of amplifying nucleic acids using promoter-containing primer sequence
    Patent number: 5766849
    Abstract: A method, composition and kit for synthesizing multiple copies of a target nucleic acid sequence autocatalytically under conditions of substantially constant temperature, ionic strength, and pH are provided in which multiple RNA copies of the target sequence autocatalytically generate additional copies using a mixture of blocked and unblocked primers and/or promoter-primers to initiate DNA and RNA synthesis, preferably with reduced non-specific product formation. The invention is useful for generating copies of a nucleic acid target sequence for purposes that include assays to quantitate specific nucleic acid sequences in clinical, environmental, forensic and similar samples, cloning and generating probes.
    Type: Grant
    Filed: November 28, 1994
    Date of Patent: June 16, 1998
    Assignee: Gen-Probe Incorporated
    Inventors: Sherrol H. McDonough, Daniel L. Kacian, Nanibhushan Dattagupta, Diane L. McAllister, Philip W. Hammond, Thomas B. Ryder
  • Detection of human immunodeficiency virus type 1
    Patent number: 5712385
    Abstract: Amplification oligonucleotides and hybridization assay probes which distinguish Human Immunodeficiency Virus type 1 from other viruses.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 27, 1998
    Assignee: Gen-Probe Incorporated
    Inventors: Sherrol H. McDonough, Thomas B. Ryder, Yeasing Yang
  • Methods for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
    Patent number: 5710029
    Abstract: Methods and kits for relating initial amounts of target nucleic acids present in a sample to target-specific amplification products. It has been discovered that the transcription-mediated amplification system is capable of producing a quantitative relationship between target input and target-specific output. Further, the present invention relates to methods for carefully controlling this relationship resulting in an unexpectedly high degree of reproducability. Also described are useful methods for extending the dynamic range of transcription-based amplification systems.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 20, 1998
    Assignee: Gen-Probe Incorporated
    Inventors: Thomas Brendan Ryder, Karen W. Shannon, Daniel Louis Kacian, Richard C. Harvey, Sherrol H. McDonough, Frank R. Gonzales, Maria R. Castillo, Elizabeth R. Billyard, Nancy Lau Liu Shen