Patents by Inventor Sherwood Gorbach

Sherwood Gorbach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Prevention of Clostridium Difficile Infection in High Risk Patients
    Publication number: 20150157653
    Abstract: The present invention relates to methods of preventing Clostridium difficile infection (COI) in a human subject who is at high risk of developing this infection, comprising administering to the subject an effective amount of the compounds described herein. In some embodiments, the subject is further receiving concomitant antibiotic therapy to prevent and/or treat an infection other than Clostridium. In some embodiments, the subject previously was treated for a Clostridium infection. In some embodiments, the compound of formula I prevents the Clostridium infection.
    Type: Application
    Filed: March 15, 2013
    Publication date: June 11, 2015
    Applicant: Optimer Pharmaceuticals, Inc.
    Inventors: Sherwood Gorbach, Pamela Sears, Yoshi Ichikawa
  • Treatment of Clostridium Difficile Infection in High Risk Patients
    Publication number: 20150141356
    Abstract: The present invention relates to methods of preventing and/or treating Clostridium difficile infection (CDI) in a subject at high risk for developing CDI including subjects receiving antibiotic therapy for a different infection comprising administering to the subject an effective amount of the compounds described herein.
    Type: Application
    Filed: November 14, 2014
    Publication date: May 21, 2015
    Inventors: Sherwood Gorbach, Pamela Sears, Yoshi Ichikawa
  • Methods of Treating Recurring Bacterial Infection
    Publication number: 20140315838
    Abstract: The present invention relates to methods of treating a recurring gastrointestinal (GI) infection of Clostridium difficile in a subject comprising administering to the subject an effective amount of the compounds of the present invention.
    Type: Application
    Filed: June 28, 2013
    Publication date: October 23, 2014
    Applicant: Optimer Pharmaceuticals, Inc.
    Inventors: Youe-Kong Shue, Sherwood Gorbach, Pamela Sears
  • Treatment of Bacterial Infections
    Publication number: 20140024609
    Abstract: The present invention relates to methods of treating a bacterial infection in a subject in need thereof comprising administering to the subject an effective amount of the compound of Formula (I) and an anti-inflammatory agent. The present invention provides pharmaceutical compositions comprising an effective amount of the compound of Formula (I) and an anti-inflammatory agent.
    Type: Application
    Filed: February 6, 2012
    Publication date: January 23, 2014
    Applicant: Optimer Pharmaceuticals ,Inc.
    Inventors: Yoshi Ichikawa, Sherwood Gorbach
  • Treatment of Clostridium Difficile Infection in Patients Undergoing Antibiotic Therapy
    Publication number: 20130331347
    Abstract: The present invention relates to methods of treating Clostridium difficile infection in a subject receiving antibiotic therapy for a different infection comprising administering to the subject an effective amount of the compounds described herein.
    Type: Application
    Filed: June 28, 2013
    Publication date: December 12, 2013
    Applicant: Optimer Pharmaceuticals, Inc.
    Inventors: Youe-Kong Shue, Sherwood Gorbach, Pamela Sears
  • Method of treating clostridium difficile-associated diarrhea
    Publication number: 20070105791
    Abstract: A method of treating a disease or disorder caused by the presence of a bacterium selected from the group consisting Clostridium species, Staphylococcus species, Enterococcus species and combinations thereof comprising administering to a patient in need an effective amount of a mixture, which comprises tiacumicin B, lipiarmycin A4, and at least one of other macrocyclic compounds:
    Type: Application
    Filed: October 23, 2006
    Publication date: May 10, 2007
    Applicant: Optimer Pharmaceuticals, Inc.
    Inventors: Pamela Sears, Starr Louise Miller-Shangle, Robert Brian Walsh, Youe-Kong Shue, Farah Babakhani, Thomas Louie, Chiu Yu-Hung, Alex Romero, Sherwood Gorbach