Patents by Inventor SHERYL LUTTRINGER
SHERYL LUTTRINGER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10781428Abstract: The present invention relates to laccase variants comprising a substitution at one or more positions corresponding to positions 9, 21, 37, 79, 102, 170, 175, 178, 179, 200, 262, 275, 276, 289, 292, 333, 357, 360, 393, 397, 418, 485, 506, and 518 of the full-length polypeptide of SEQ ID NO: 2. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.Type: GrantFiled: December 2, 2015Date of Patent: September 22, 2020Assignee: NOVOZYMES A/SInventors: Daniel Held, Sheryl Luttringer, Tammy Doty
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Publication number: 20180282708Abstract: The present invention relates to laccase variants comprising a substitution at one or more positions corresponding to positions 9, 21, 37, 79, 102, 170, 175, 178, 179, 200, 262, 275, 276, 289, 292, 333, 357, 360, 393, 397, 418, 485, 506, and 518 of the full-length polypeptide of SEQ ID NO: 2. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.Type: ApplicationFiled: December 2, 2015Publication date: October 4, 2018Applicant: NOVOZYMES A/SInventors: Daniel HELD, Sheryl LUTTRINGER, Tammy DOTY
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Patent number: 9447440Abstract: The present invention relates to isolated polypeptides having bicarbonate transporter activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, and methods of producing C4-dicarboxylic acids, such as malic acid.Type: GrantFiled: January 21, 2014Date of Patent: September 20, 2016Assignee: Novozymes, Inc.Inventors: Amanda Fischer, Stephen Brown, Sheryl Luttringer
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Patent number: 8999685Abstract: The present invention relates to methods of producing a C4 dicarboxylic acid, comprising: (a) cultivating a filamentous fungal host cell comprising a polynucleotide selected from the group consisting of a heterologous first polynucleotide encoding a C4 dicarboxylic acid transporter, a heterologous second polynucleotide encoding a malate dehydrogenase, and a heterologous third polynucleotide encoding a pyruvate carboxylase; wherein the filamentous fungal host cell is capable of secreting increased levels of the C4 dicarboxylic acid compared to the filamentous fungal host cell without the heterologous polynucleotide when cultivated under the same conditions; and (b) recovering the C4 dicarboxylic acid. The present invention also relates to methods for increasing C4 dicarboxylic acid production, filamentous fungal host cells and malate dehydrogenase variants.Type: GrantFiled: May 5, 2014Date of Patent: April 7, 2015Assignee: Novozymes, Inc.Inventors: Stephen Brown, Sheryl Luttringer, Debbie Yaver, Alan Berry
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Publication number: 20150024446Abstract: The present invention relates to methods of producing a C4 dicarboxylic acid, comprising: (a) cultivating a filamentous fungal host cell comprising a polynucleotide selected from the group consisting of a heterologous first polynucleotide encoding a C4 dicarboxylic acid transporter, a heterologous second polynucleotide encoding a malate dehydrogenase, and a heterologous third polynucleotide encoding a pyruvate carboxylase; wherein the filamentous fungal host cell is capable of secreting increased levels of the C4 dicarboxylic acid compared to the filamentous fungal host cell without the heterologous polynucleotide when cultivated under the same conditions; and (b) recovering the C4 dicarboxylic acid. The present invention also relates to methods for increasing C4 dicarboxylic acid production, filamentous fungal host cells and malate dehydrogenase variants.Type: ApplicationFiled: October 9, 2014Publication date: January 22, 2015Inventors: Stephen Brown, Sheryl Luttringer, Debbie Yaver, Alan Berry
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Publication number: 20140234925Abstract: The present invention relates to methods of producing a C4 dicarboxylic acid, comprising: (a) cultivating a filamentous fungal host cell comprising a polynucleotide selected from the group consisting of a heterologous first polynucleotide encoding a C4 dicarboxylic acid transporter, a heterologous second polynucleotide encoding a malate dehydrogenase, and a heterologous third polynucleotide encoding a pyruvate carboxylase; wherein the filamentous fungal host cell is capable of secreting increased levels of the C4 dicarboxylic acid compared to the filamentous fungal host cell without the heterologous polynucleotide when cultivated under the same conditions; and (b) recovering the C4 dicarboxylic acid. The present invention also relates to methods for increasing C4 dicarboxylic acid production, filamentous fungal host cells and malate dehydrogenase variants.Type: ApplicationFiled: May 5, 2014Publication date: August 21, 2014Applicant: Novozymes, Inc.Inventors: Stephen Brown, Sheryl Luttringer, Debbie Yaver, Alan Berry
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Patent number: 8741611Abstract: The present invention relates to methods of producing a C4 dicarboxylic acid, comprising: (a) cultivating a filamentous fungal host cell comprising a polynucleotide selected from the group consisting of a heterologous first polynucleotide encoding a C4 dicarboxylic acid transporter, a heterologous second polynucleotide encoding a malate dehydrogenase, and a heterologous third polynucleotide encoding a pyruvate carboxylase; wherein the filamentous fungal host cell is capable of secreting increased levels of the C4 dicarboxylic acid compared to the filamentous fungal host cell without the heterologous polynucleotide when cultivated under the same conditions; and (b) recovering the C4 dicarboxylic acid. The present invention also relates to methods for increasing C4 dicarboxylic acid production, filamentous fungal host cells and malate dehydrogenase variants.Type: GrantFiled: August 27, 2010Date of Patent: June 3, 2014Assignee: Novozymes, Inc.Inventors: Stephen Brown, Sheryl Luttringer, Debbie Yaver, Alan Berry
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Publication number: 20140134688Abstract: The present invention relates to isolated polypeptides having bicarbonate transporter activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, and methods of producing C4-dicarboxylic acids, such as malic acid.Type: ApplicationFiled: January 21, 2014Publication date: May 15, 2014Applicant: Novozymes, Inc.Inventors: Amanda Fischer, Stephen Brown, Sheryl Luttringer
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Patent number: 8722387Abstract: The present invention relates to isolated polypeptides having bicarbonate transporter activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, and methods of producing C4-dicarboxylic acids, such as malic acid.Type: GrantFiled: February 28, 2012Date of Patent: May 13, 2014Assignee: Novozymes, Inc.Inventors: Amanda Fischer, Stephen Brown, Sheryl Luttringer
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Patent number: 8663956Abstract: Provided herein are host cells comprising carbonic anhydrase activity, wherein the cells are capable of producing C4-dicarboxylic acid. Also provided are methods of producing C4-dicarboxylic acid comprising (a) cultivating the host cells having carbonic anhydrase activity in a medium under suitable conditions to produce C4-dicarboxylic acid; and (b) recovering the C4-dicarboxylic acid.Type: GrantFiled: August 17, 2012Date of Patent: March 4, 2014Assignee: Novozymes, Inc.Inventors: Sarah McFarland, Stephen Brown, Sheryl Luttringer
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Publication number: 20130288321Abstract: The present invention relates to methods of producing C4-dicarboxylic acids, such as malic acid, comprising: (a) cultivating a host cell comprising a polynucleotide encoding a C4-dicarboxylic acid transporter; and (b) recovering the C4-dicarboxylic acid. The present invention also relates to methods for increasing C4-dicarboxylic acid production, as well as host cells comprising the polynucleotides.Type: ApplicationFiled: June 25, 2013Publication date: October 31, 2013Inventors: Sheryl Luttringer, Debbie Yaver
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Patent number: 8497103Abstract: The present invention relates to methods of producing C4-dicarboxylic acids, such as malic acid, comprising: (a) cultivating a host cell comprising a polynucleotide encoding a C4-dicarboxylic acid transporter; and (b) recovering the C4-dicarboxylic acid. The present invention also relates to methods for increasing C4-dicarboxylic acid production, as well as host cells comprising the polynucleotides.Type: GrantFiled: June 21, 2011Date of Patent: July 30, 2013Assignee: Novozymes, Inc.Inventors: Sheryl Luttringer, Debbie Yaver
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Publication number: 20130059353Abstract: Provided herein are host cells comprising carbonic anhydrase activity, wherein the cells are capable of producing C4-dicarboxylic acid. Also provided are methods of producing C4-dicarboxylic acid comprising (a) cultivating the host cells having carbonic anhydrase activity in a medium under suitable conditions to produce C4-dicarboxylic acid; and (b) recovering the C4-dicarboxylic acid.Type: ApplicationFiled: August 17, 2012Publication date: March 7, 2013Applicant: NOVOZYMES, INC.Inventors: Sarah McFarland, Stephen Brown, Sheryl Luttringer
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Publication number: 20120219999Abstract: The present invention relates to isolated polypeptides having bicarbonate transporter activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, and methods of producing C4-dicarboxylic acids, such as malic acid.Type: ApplicationFiled: February 28, 2012Publication date: August 30, 2012Applicant: NOVOZYMES, INC.Inventors: Amanda Fischer, Stephen Brown, Sheryl Luttringer
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Publication number: 20110312046Abstract: The present invention relates to methods of producing C4-dicarboxylic acids, such as malic acid, comprising: (a) cultivating a host cell comprising a polynucleotide encoding a C4-dicarboxylic acid transporter; and (b) recovering the C4-dicarboxylic acid. The present invention also relates to methods for increasing C4-dicarboxylic acid production, as well as host cells comprising the polynucleotides.Type: ApplicationFiled: June 21, 2011Publication date: December 22, 2011Applicant: NOVOZYMES, INC.Inventors: SHERYL LUTTRINGER, DEBBIE YAVER
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Publication number: 20110053233Abstract: The present invention relates to methods of producing a C4 dicarboxylic acid, comprising: (a) cultivating a filamentous fungal host cell comprising a polynucleotide selected from the group consisting of a heterologous first polynucleotide encoding a C4 dicarboxylic acid transporter, a heterologous second polynucleotide encoding a malate dehydrogenase, and a heterologous third polynucleotide encoding a pyruvate carboxylase; wherein the filamentous fungal host cell is capable of secreting increased levels of the C4 dicarboxylic acid compared to the filamentous fungal host cell without the heterologous polynucleotide when cultivated under the same conditions; and (b) recovering the C4 dicarboxylic acid. The present invention also relates to methods for increasing C4 dicarboxylic acid production, filamentous fungal host cells and malate dehydrogenase variants.Type: ApplicationFiled: August 27, 2010Publication date: March 3, 2011Applicant: NOVOZYMES, INC.Inventors: STEPHEN BROWN, SHERYL LUTTRINGER, DEBBIE YAVER, ALAN BERRY