Patents by Inventor Sheung Fan

Sheung Fan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070248538
    Abstract: This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of primary and metastatic human tumor cells; and most particularly to the use of an isolated monoclonal antibody or cancerous disease modifying antibodies (CDMAB) thereof, optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response in such human tumors, e.g. any primary or metastatic tumor sites which arise from hepatocytes. The invention further relates to binding assays which utilize the CDMAB of the instant invention.
    Type: Application
    Filed: April 11, 2007
    Publication date: October 25, 2007
    Inventors: David Young, Daad Sayegh, Sheung Fan, Ronnie Poon, Terence Lee
  • Publication number: 20070189964
    Abstract: This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of primary and metastatic human tumor cells; and most particularly to the use of an isolated monoclonal antibody or cancerous disease modifying antibodies (CDMAB) thereof, optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response in such human tumors, e.g. any primary or metastatic tumor sites which arise from hepatocytes. The invention further relates to binding assays which utilize the CDMAB of the instant invention.
    Type: Application
    Filed: March 9, 2007
    Publication date: August 16, 2007
    Inventors: David Young, Daad Sayegh, Sheung Fan, Ronnie Poon, Terence Lee
  • Publication number: 20060269481
    Abstract: This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of primary and metastatic human tumor cells; and most particularly to the use of an isolated monoclonal antibody or cancerous disease modifying antibodies (CDMAB) thereof, optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response in such human tumors, e.g. any primary or metastatic tumor sites which arise from hepatocytes. The invention further relates to binding assays which utilize the CDMAB of the instant invention.
    Type: Application
    Filed: July 26, 2006
    Publication date: November 30, 2006
    Inventors: David Young, Susan Hahn, Helen Findlay, Luis daCruz, Daad Sayegh, Sheung Fan, Ronnie Poon, Terence Lee
  • Publication number: 20050244839
    Abstract: This invention further provides methods for determining whether an agent causes a reduction in the activity of a Granulin-Epithelin Precursor (GEP) protein in a cell. This invention also provides methods for reducing the expression of Granulin-Epithelin Precursor (GEP) protein in a cell. This invention also provides methods for determining whether a subject is afflicted with Hepatocellular carcinoma (HCC). This invention provides methods for determining whether a subject is afflicted with Hepatocellular carcinoma (HCC) This invention further provides a method for treating a subject afflicted with Hepatocellular carcinoma (HCC) comprising administering to the subject a therapeutically effective amount of an agent which specifically interferes with the expression of the Granulin-Epithelin Precursor (GEP) protein in the tumor cells of the subject.
    Type: Application
    Filed: April 29, 2004
    Publication date: November 3, 2005
    Inventors: Siu Cheung, Sheung Fan
  • Publication number: 20050089895
    Abstract: This invention provides a composition comprising the following polynucleotide probes: IL7R (AA485865), NDRG1 (AA486403), EST1 (H50345), TRPC1 (AA017132), GFRA1 (AA512935), EST2 (AA454543), CLDN10 (R54559), DNALI1 (R93087), RBP5 (AA453198), EST3 (AA621761), EST4 (N63706), PCOLCE (AA670200), TDO2 (T72398), EST5 (T47454), HIST1H2BD (N33927), PXMP2 (N70714), ACAS2 (AA455146), ANAPC7 (T68445), EST6 (AA576580), RBP5 (N92148), ANXA1 (H63077), CKB (AA894557), ITGBL1 (N52533), KPNA2 (AA676460), EST7 (W90740) and MEG3 (W85841). This invention further provides methods for determining the likelihood of recurrence of hepatocellular carcinoma (HCC) in a subject afflicted with HCC, for determining the likelihood of death of a subject afflicted with HCC or for determining whether to administer adjuvant therapy.
    Type: Application
    Filed: August 12, 2004
    Publication date: April 28, 2005
    Inventors: Siu Cheung, Sheung Fan
  • Publication number: 20020199055
    Abstract: A buffer manager provides address information for reading and writing data to an SDRAM. The address information is translated from a flat memory address space into an SDRAM address space. The buffer manager operates based upon a first clock and the SDRAM operates based upon a second clock. Accordingly, a synchronization circuit synchronizes the data. The translation of address information occurs simultaneously with the synchronization of data.
    Type: Application
    Filed: June 6, 2002
    Publication date: December 26, 2002
    Inventor: Sheung-Fan Wen
  • Patent number: 6484248
    Abstract: A buffer manager provides address information for reading and writing data to an SDRAM. The address information is translated from a flat memory address space into an SDRAM address space. The buffer manager operates based upon a first clock and the SDRAM operates based upon a second clock. Accordingly, a synchronization circuit synchronizes the data. The translation of address information occurs simultaneously with the synchronization of data.
    Type: Grant
    Filed: June 6, 2002
    Date of Patent: November 19, 2002
    Assignee: National Semiconductor Corporation
    Inventor: Sheung-Fan Wen
  • Patent number: 6418518
    Abstract: A buffer manager provides address information for reading and writing data to an SDRAM. The address information is translated from a flat memory address space into an SDRAM address space. The buffer manager operates based upon a first clock and the SDRAM operates based upon a second clock. Accordingly, a synchronization circuit synchronizes the data. The translation of address information occurs simultaneously with the synchronization of data.
    Type: Grant
    Filed: September 18, 1998
    Date of Patent: July 9, 2002
    Assignee: National Semiconductor Corporation
    Inventor: Sheung-Fan Wen
  • Patent number: 6259650
    Abstract: A FIFO stack is implemented using a DPRAM. One of the ports of the DPRAM is used to add elements to the FIFO stack, and the other port is used to remove elements from the FIFO stack. The ports operate in separate clock domains. A synchronization circuit coordinates the read and write operations across the clock domains.
    Type: Grant
    Filed: August 31, 2000
    Date of Patent: July 10, 2001
    Assignee: National Semiconductor Corporation
    Inventor: Sheung-Fan Wen
  • Patent number: 6212122
    Abstract: A FIFO stack is implemented using a DPRAM. One of the ports of the DPRAM is used to add elements to the FIFO stack, and the other port is used to remove elements from the FIFO stack. The ports operate in separate clock domains. A synchronization circuit coordinates the read and write operations across the clock domains.
    Type: Grant
    Filed: August 31, 2000
    Date of Patent: April 3, 2001
    Assignee: National Semiconductor Corporation
    Inventor: Sheung-Fan Wen
  • Patent number: 6205511
    Abstract: A buffer manager divides a memory space into a plurality of buffers. Each buffer occupies a plurality of sequential memory locations. The sequential memory locations include a start and an end address. To write data to a buffer, the buffer manager provides a start address and burst size to an address translator. The address translator converts the start address and the burst size to SDRAM memory address locations. The start and end address of each buffer is mapped to a different bank in the SDRAM memory.
    Type: Grant
    Filed: September 18, 1998
    Date of Patent: March 20, 2001
    Assignee: National Semiconductor Corp.
    Inventor: Sheung-Fan Wen
  • Patent number: 6166963
    Abstract: A FIFO stack is implemented using a DPRAM. One of the ports of the DPRAM is used to add elements to the FIFO stack, and the other port is used to remove elements from the FIFO stack. The ports operate in separate clock domains. A synchronization circuit coordinates the read and write operations across the clock domains.
    Type: Grant
    Filed: September 17, 1998
    Date of Patent: December 26, 2000
    Assignee: National Semiconductor Corporation
    Inventor: Sheung-Fan Wen
  • Patent number: 6134155
    Abstract: A FIFO stack is implemented using a DPRAM. One of the ports of the DPRAM is used to add elements to the FIFO stack, and the other port is used to remove elements from the FIFO stack. The ports operate in separate clock domains. A synchronization circuit coordinates the read and write operations across the clock domains.
    Type: Grant
    Filed: September 28, 1999
    Date of Patent: October 17, 2000
    Assignee: National Semiconductor Corporation
    Inventor: Sheung-Fan Wen