Abstract: The present invention provides an anti-PD-L1/VEGF bispecific antibody and a use thereof. Specifically, the present invention provides a bifunctional antibody, comprising: (a) anti-PD-L1 antibody or element; and (b) an anti-VEGF antibody or element linked to the anti-PD-L1 antibody or element. The bifunctional antibody of the present invention can simultaneously bind to VEGF and PD-L1, thereby exerting a therapeutic effect on VEGF and PD-L1-positive tumor cells (especially malignant tumor cells).

Abstract: Embodiments of the present disclosure provide a rotary base, a ranging device, and a mobile robot, which include a mount, a drive assembly, and a processing module. The mount encloses an accommodation portion, wherein an accommodation recess is defined in the accommodation portion. The drive assembly includes a rotor being arranged in the accommodation recess and a rotation portion being connected to the rotor. The processing module is arranged on the mount and connected to the drive assembly, wherein the processing module is configured to detect a commutation signal of the drive assembly to acquire a rotation speed and a rotation angle of the rotation portion.

Abstract: Poly-bit cells and methods for forming the same are provided. In one example, a method for forming a poly-bit cell includes identifying layouts in a library of single-bit cells having one or more of a different functionality and a different drive that are combinable; storing, in memory, layouts that are combinable; and creating layouts of poly-bit cells from the stored combinable single-bit cells. Each poly-bit cell combined from layouts of at least two single-bit cells has one or more of a different functionality and a different drive.

Abstract: A PD-L1 antigen binding protein and an application thereof. The antigen binding protein has one or more of the following properties: binding to a PD-L1 protein at an EC50 value of 0.07 ?g/ml or above; blocking binding between the PD-L1 protein and a PD-1 protein; promoting the activation of a T cell; and inhibiting the volume increase of the in vivo tumor. An application of the antigen binding protein in the preparation of a drug for treating tumor.

Abstract: The present disclosure provides an information processing method and apparatus, an electronic device, and a storage medium. The present disclosure provides an information processing method. The method includes: receiving a first document, so as to perform preset processing on the first document; determining, based on document content of the first document, or the document content and associated information of the first document, whether there is an alert item in the first document that satisfies a preset condition; and displaying the first document in association with the alert item in response to there being the alert item in the first document, where the alert item is displayed in association with category information.

Abstract: A production line for producing components to a high standard of cleanliness and sealed and protected in that state includes a loading device, a cleaning device, a detecting device, a pasting device, a heat-sealing device, a packing device, and transfer devices of the production line. The production line automatically processes the components for obtaining components with the high cleanliness. By the processes of protective film pasting, heat-sealing, and packing, the components may be further protected from subsequent pollution. A method for producing components with a high cleanliness applied to the production line is also disclosed.

Abstract: The present disclosure provides a visual analysis system based on a discipline assessment report, and relates to the technical field of discipline assessment. The visual analysis system based on a discipline assessment report includes a data acquisition unit. An output end of the data acquisition unit is electrically connected to an input end of a data preprocessing unit, and an output end of the data preprocessing unit is electrically connected to an input end of a central processing unit. According to the visual analysis system based on a discipline assessment report, development and changes of the discipline in a project corresponding to the indicator are accurately determined, and a clear plan and development goal are made for overall development of the discipline. Therefore, the overall discipline assessment and a follow-up development process are more clear and distinct.

Abstract: The present invention discloses a recombinant RBD trimer protein capable of simultaneously generating cross neutralization activity for various severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic strains. The RBD trimer protein is taken as an antigen and supplemented with an adjuvant to immunize an organism, so that a high-titer neutralizing antibody aiming at various SARS-CoV-2 epidemic strains can be generated at the same time, and the antibody has a certain broad-spectrum property and can be used for treating and/or preventing SARS-CoV-2 infection and/or coronavirus disease 2019.

Abstract: A preparation method of soft carbon comprises heating heavy oil to raw coke under a condition of 480° C.-550° C., heating the raw coke to 850° C.-900° C. at a first heating rate of 3° C./min to 5° C./min and holding the temperature for 4 hours or more to obtain a carbon-containing material, grinding and grading the carbon-containing material to obtain a carbon-containing powder, heating the carbon-containing powder to 1030° C.-1220° C. at a second heating rate of 3° C./min to 10° C./min and holding the temperature for 4 hours or more to obtain a carbon material powder, and adding pitch to the carbon material powder, and then heating it to 1030° C.-1220° C. at a third heating rate of 0.90° C./min to 1.25° C./min and holding the temperature for 5 hours or more to obtain soft carbon.

Abstract: Passive monitoring the integrity of current sensing devices and associated circuitry in GFCI and AFCI protective devices is provided. A protection circuit interrupter employs a capacitively coupled noise signal obtained by an arrangement of one or both of line side arms relative to a Rogowski coil. The noise signal is monitored while the line and load sides of a protective circuit interrupter are disconnected, and the connection of the line and load sides disabled if the noise signal fails to correlate sufficiently to a reference noise cycle. When the line and load sides are connected, the RMS value of the observed current signal is monitored such that the line and load sides are disconnected if the observed current signal fails to meet an RMS threshold. The observed current signal is compensated by subtracting the reference noise cycle prior to monitoring for the fault condition applicable to the protective device.

Abstract: A virtual reality acupuncture system contains a virtual reality device comprising: a head-mounted display for viewing a virtual scene model and a mannequin, and a joystick for tracking hand movements for needle insertion determination; an computing host that transmits data with a head-mounted display and constructs an acupoint database, and an acupuncture virtual reality application which is executed to build a virtual reality model, in which the acupuncture virtual reality application constructs a situational scene model for simulating the actual condition of the consultation room; and a virtual 3D spherical acupoint model of the human body, which has a sphere area located at a certain depth below the skin surface, and has a skin distance model, so that the needle can sense the distance depth after touching the skin, which can be used to determine whether the needle position is not outside the sphere area.

Abstract: This application discloses a fault protection method, including: A first node determines that a first cross-domain node is faulty. The first node is a head node of a segment routing best effort SR-BE service tunnel, the SR-BE tunnel is a cross-domain tunnel that passes through a first IGP domain and a second IGP domain, the SR-BE tunnel passes through the first cross-domain node, and the first cross-domain node is a node that crosses the first IGP domain and the second IGP domain. The first node switches a service transmission path from the SR-BE tunnel to a backup tunnel. The backup tunnel does not pass through the first cross-domain node, and the backup tunnel is a tunnel with a strict explicit path.

Abstract: A method for prelithiating a soft carbon negative electrode includes the steps of: disposing the soft carbon negative electrode and a lithium metal piece spaced apart from each other with a lithium-containing electrolyte present therebetween; prelithiating the soft carbon negative electrode at a first constant C-rate until a voltage thereof is reduced to a first predetermined voltage not greater than 0.3 V vs. Li/Li+, the first constant C-rate being not greater than 5 C; prelithiating the soft carbon negative electrode at a second constant C-rate until the voltage thereof is reduced to a second predetermined voltage lower than the first predetermined voltage, the second constant C-rate being not greater than 0.2 C and being less than the first constant C-rate; and prelithiating the soft carbon negative electrode at a prelithiation constant voltage which is not greater than the second predetermined voltage, thereby completing prelithiation of the soft carbon negative electrode.

Abstract: A method for making a carbon material for an anode of a lithium-ion secondary battery includes a sequence of: a) heating a heavy hydrocarbon oil to obtain a green coke, b) a heating the green coke to form a carbon-containing material, c) grinding the carbon-containing material into a powder, and collecting a portion of the powder, d) heating the portion of the powder to obtain a carbonaceous powder, and e) adding pitch to the carbonaceous powder and heating the pitch-contained carbonaceous powder. A lithium-ion secondary battery, which includes the anode having the carbon material, is also disclosed.

Abstract: Passive monitoring the integrity of current sensing devices and associated circuitry in GFCI and AFCI protective devices is provided. A protection circuit interrupter employs a capacitively coupled noise signal obtained by an arrangement of one or both of line side arms relative to a Rogowski coil. The noise signal is monitored while the line and load sides of a protective circuit interrupter are disconnected, and the connection of the line and load sides disabled if the noise signal fails to correlate sufficiently to a reference noise cycle. When the line and load sides are connected, the RMS value of the observed current signal is monitored such that the line and load sides are disconnected if the observed current signal fails to meet an RMS threshold. The observed current signal is compensated by subtracting the reference noise cycle prior to monitoring for the fault condition applicable to the protective device.