Abstract: Disclosed is a mutant of a wild-type RSV F protein. The binding experiment of a pre-fusion conformation trimer-specific monoclonal antibody AM14 shows that the mutant provided in embodiments can have strong activity of binding to the AM14 monoclonal antibody, while the wild-type RSV F protein before artificial mutation has no activity of binding to the AM14 monoclonal antibody. The accelerated stability test result shows that the activity of binding of the mutant provided in the embodiments when placed in a 37° C. environment for four weeks to the AM14 monoclonal antibody does not change obviously. The animal immune experiment result shows that compared with the wild-type RSV F protein before artificial mutation, the mutant provided in the embodiments can induce production of a neutralizing antibody having a higher titer.

Abstract: The present application discloses a back contact solar cell and a photovoltaic module. An example back contact solar cell includes a semiconductor substrate, a first doped semiconductor layer, a second doped semiconductor layer, and a dielectric layer. The first doped semiconductor layer is disposed on a first region and a third region. The second doped semiconductor layer is disposed on a second region and the third region. A doping type of the first doped semiconductor layer is opposite to that of the second doped semiconductor layer. On the third region, the first doped semiconductor layer and the second doped semiconductor layer overlap in a thickness direction of the semiconductor substrate to form a stacked structure. The dielectric layer is disposed at least between the first doped semiconductor layer and the second doped semiconductor layer. A leakage path is disposed in the dielectric layer.

Abstract: A water-in-oil emulsified cosmetic containing the following components (A), (B), and (C): (A) an UV scattering agent having a hydrophobicity degree of 73% or less in accordance with methanol titration; (B) an amphiphilic substance which is solid at 25° C.; and (C) an aqueous-phase component. The component (A) contains dimethicone-treated zinc oxide microparticles (A1), in which a mass ratio of a content of the component (A1) to a content of the component (A) [component (A1)/component (A)] is 0.38 or more, the component (C) has a surface tension of less than 0.0728 N/m, and a content of the component (C) is 16 mass % or more.

Abstract: Disclosed are a step-down and phase-shifting transformer and an operational control method thereof. The step-down and phase-shifting transformer is connected to grids on at least two sides and at least includes a first winding, a second winding, and a third winding. The third winding is provided with a tap-position adjustment switch, the third winding is magnetically coupled to the first winding and the second winding, and the third winding is electrically connected to the first winding or the second winding, such that phase angle control and transmission power control between grids on different sides can be realized by adjusting the tap-position adjustment switch on the basis of voltage transformation.

Abstract: Disclosed is a conjugate of a nucleotide analog-containing double-stranded RNAi analog, and specifically disclosed are a sequence composition and a ligand structure of a conjugate of the double-stranded RNAi analog.

Abstract: The invention provides an illumination angle adjustment component and an angle-adjustable luminaire. The illumination angle adjustment component comprises a support, a light source and an optical component. The light source emits light that is at least partially incident on the optical component, and the light is re-directed and emitted through the optical component. The light source and the optical component are both mounted on the support, and at least one of the light source and the optical component is rotatable and/or swingable relative to the support to change an angle of emergence of the light emitted from the optical component. The illumination angle adjustment component can improve the universality and ensure the heat dissipation effect.

Abstract: An attack detection and source tracing method includes acquiring entities in a target network environment and interaction event information between the entities and constructing a network event graph with the entities and the interaction event information; determining a graph embedding vector of each interaction event information in the network event graph as feature information based on a preset attack feature recognition model and determining an attack event in the network event graph according to the feature information; determining dependencies between the attack event and remaining interaction event information in the network event graph and searching for a corresponding interaction event information as source tracing information of the attack event according to the dependencies.

Abstract: An oral care device, an operation control method thereof, and a computer readable storage medium are provided. The oral care device includes a processor, a driving component and a care element. The operation control method includes step: controlling the driving shaft to have different cleaning parameters in different motion orientations based on the motion orientations of the driving shaft. Each of the motion orientations of the driving shaft includes at least one of an absolute position, a relative position, a motion area, and a motion direction. Each of the cleaning parameters includes at least one of a first parameter representing a cleaning effect, a second parameter representing a cleaning time, a third parameter representing a protection effect, and a fourth parameter representing a cleaning range.

Abstract: Provided are an active defense system and method for an unknown threat. The system includes an intelligent threat early-warning module (10), an unknown threat detection module (20) and a self-adaption defense processing module (30). The intelligent threat early-warning module (10) is configured to perform threat prediction on a power grid situation data set collected from a power information network in real time to obtain threat early-warning information and send the information to the unknown threat detection module (20). The unknown threat detection module (20) is configured to perform threat detection and analysis on collected unknown threat network data when receiving the threat early-warning information to generate a threat analysis report and send the report to the self-adaption defense processing module (30). The self-adaption defense processing module (30) is configured to trigger a defense processing operation corresponding to a preset threat defense strategy according to the threat analysis report.

Abstract: The present application discloses a solar cell and a photovoltaic module, and relates to the field of photovoltaic technologies. As an example, a solar cell includes a semiconductor substrate, a first doped semiconductor portion, a first anti-reflection layer, and a second anti-reflection layer. The semiconductor substrate has a first surface having a first region and a second region that do not overlap. The first doped semiconductor portion is arranged on the first region. The first anti-reflection layer is arranged on a surface of the first doped semiconductor portion. The second anti-reflection layer is arranged on the second region. A difference between a surface reflectivity of a side of the first anti-reflection layer facing away from the semiconductor substrate and a surface reflectivity of a side of the second anti-reflection layer facing away from the semiconductor substrate is greater than or equal to 0.5% and less than or equal to 40%.

Abstract: An attack detection and source tracing method includes acquiring entities in a target network environment and interaction event information between the entities and constructing a network event graph with the entities and the interaction event information; determining a graph embedding vector of each interaction event information in the network event graph as feature information based on a preset attack feature recognition model and determining an attack event in the network event graph according to the feature information; determining dependencies between the attack event and remaining interaction event information in the network event graph and searching for a corresponding interaction event information as source tracing information of the attack event according to the dependencies.

Abstract: Provided is an isolated antigen-binding protein, which contains a first binding domain and a second binding domain, wherein the first binding domain is capable of binding to a CD39 protein, and the second binding domain is capable of binding to a CD73 protein. Also provided are a nucleic acid molecule encoding the isolated antigen-binding protein, a vector and a cell containing the nucleic acid molecule, a pharmaceutical composition containing the isolated antigen-binding protein, a method for preparing the isolated antigen-binding protein, and the use of the isolated antigen-binding protein.

Abstract: This application provides a lens module. The lens module includes a first lens module and a second lens module, and the first lens module and the second lens module are arranged along an optical axis. The first lens module is configured to implement a long focal length, and the second lens module is configured to implement focusing. During specific disposition, the first lens module includes a first lens, and a light incident side surface of the first lens includes a light transmission region and a first reflection region; a light outgoing side surface of the first lens includes a second reflection region and a light outgoing region; and the first reflection region and the second reflection region are configured to refract light incident into the first lens. The second lens module includes at least one second lens, and the at least one second lens is a focusing lens.

Abstract: In one aspect, a process for preparing a Mn4+ doped phosphor of Formula I is provided Ax[MFy]:Mn4+ (I). The process includes combining a first aqueous solution including a source of Mn with a second solution including H2MF6 to form a third solution, and combining the third solution with a fourth solution including a source of A to form the Mn4+ doped phosphor, where A is Li, Na, K, Rb, Cs, or a combination thereof; M is Si, Ge, Sn, Ti, Zr, Al, Ga, In, Sc, Y, La, Nb, Ta, Bi, Gd, or a combination thereof; x is the absolute value of the charge of the [MFy] ion; and y is 5, 6 or 7. Methods, phosphors and devices are also provided.

Abstract: A control method includes in response to a mode switch operation of a user, switching to a first control mode or a second control mode, in response to a position adjustment of an operation member of a control terminal, adjusting a position or an attitude of an aerial vehicle in a control direction corresponding to the operation member, in the first control mode, in response to the operation member being at a preset first initial position, controlling the aerial vehicle to maintain the position or the attitude unchanged in the control direction, and in the second control mode, in response to the aerial vehicle being in an initial status in the control direction and the operation member being in a preset second initial position different from the first initial position, controlling the aerial vehicle to maintain the position or the attitude unchanged in the control direction.

Abstract: Embodiments of the present disclosure relate to a method for molecular docking and an electronic device. The method comprises: determining a first binding site on a first molecular surface of a first molecule and a second binding site on a second molecular surface of a second molecule based on a first time-dependent evolution multiscale feature of the first molecule and a second time-dependent evolution multiscale feature of the second molecule; obtaining a first chemical feature of the first binding site and a second chemical feature of the second binding site; determining a functional mapping matrix between the first chemical feature and the second chemical feature through functional mapping; determining a correspondence between the first binding site and the second binding site based on the functional mapping matrix; and docking the first molecule and the second molecule through the first binding site and the second binding site based on the correspondence.

Abstract: Embodiments of the present disclosure relate to a molecular representation method and an electronic device. The molecular representation method comprises: determining a molecular surface of a molecule, the molecular surface being a continuous Riemannian manifold and the molecular surface comprising a plurality of discrete surface nodes; determining a geometric feature of the molecule based on the molecular surface; determining a chemical feature of the molecule by mapping atomic information inside the molecule to the plurality of surface nodes; determining a unified feature of the molecule by integrating the geometric feature and the chemical feature; and determining a time-dependent evolution multi-scale feature of the molecule based on the unified feature by using a time-dependent evolution neural network model.

Abstract: The present invention discloses an S-RBD trimer protein for a novel coronavirus. The trimer protein is composed of amino acid fragments at positions 319-537 in an RBD domain of an S protein of the novel coronavirus n a trimer form. A body is immunized with a vaccine prepared in the present invention taking the S-RBD trimer protein as an antigen and supplemented by an adjuvant, and then a hic neutralizing antibody for the novel coronavirus may be produced and may be used for treating and/or preventing novel coronavirus (SARS-CoV-2) infection and/or a novel coronavirus disease.

Abstract: Provided are an active defense system and method for an unknown threat. The system includes an intelligent threat early-warning module (10), an unknown threat detection module (20) and a self-adaption defense processing module (30). The intelligent threat early-warning module (10) is configured to perform threat prediction on a power grid situation data set collected from a power information network in real time to obtain threat early-warning information and send the information to the unknown threat detection module (20). The unknown threat detection module (20) is configured to perform threat detection and analysis on collected unknown threat network data when receiving the threat early-warning information to generate a threat analysis report and send the report to the self-adaption defense processing module (30). The self-adaption defense processing module (30) is configured to trigger a defense processing operation corresponding to a preset threat defense strategy according to the threat analysis report.

Abstract: A high extinction-ratio rotator includes a collimator that can collimate a signal light from an optical fiber, a pair of polarizing splitting prisms that include a first birefringence crystal wedge and a second birefringent crystal wedge, that can separate two orthogonal polarization components of the signal light into a vertically polarized light and a horizontally polarized light, a non-reciprocal 45-degree polarization rotator which the vertically polarized light and the horizontally polarized light exiting the pair of polarizing splitting prisms pass through, and a reflector. The vertically polarized light and the horizontally polarized light exiting the non-reciprocal 45-degree polarization rotator intersect on a surface of the reflector and are reflected back into the non-reciprocal 45-degree polarization rotator.