Patents by Inventor Shi Su

Shi Su has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of epothilones, intermediates thereto, analogues and uses thereof
    Publication number: 20080004450
    Abstract: The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention further provides novel compositions based on analogues of the epothilones and methods for the treatment of cancer and cancer which has developed a multidrug-resistant phenotype.
    Type: Application
    Filed: January 11, 2007
    Publication date: January 3, 2008
    Inventors: Samuel Danishefsky, Peter Bertinato, Dai-Shi Su, Dong Meng, Ting-Chao Chou, Ted Kamenecka, Erik Sorensen, Aaron Balog, Kenneth Savin
  • HIV reverse transcriptase inhibitors
    Publication number: 20070021442
    Abstract: Compounds having the structure: are HIV reverse transcriptase inhibitors, wherein A, X, Y, Z, R1 and R2 are defined herein. The compounds and their pharmaceutically acceptable salts are useful in the inhibition of HIV reverse transcriptase, the prophylaxis and treatment of infection by HIV and in the prophylaxis, delay in the onset, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
    Type: Application
    Filed: July 17, 2006
    Publication date: January 25, 2007
    Inventors: Sandeep Saggar, John Sisko, Thomas Tucker, Robert Tynebor, Dai-Shi Su, Neville Anthony
  • Sulfonyl substituted n-(biarylmethyl) aminocyclopropanecarboxamides
    Publication number: 20060247229
    Abstract: N-(Sulfonyloxybiarylmethyl)aminocyclopropanecarboxamide derivatives are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway.
    Type: Application
    Filed: August 3, 2004
    Publication date: November 2, 2006
    Inventors: Neville Anthony, Robert Gomez, Samson Jolly, John Lim, Dai-shi Su
  • N-biphenylmethyl aminocycloalkanecarboxamide derivatives
    Patent number: 7091380
    Abstract: N-Biphenyl(substituted methyl) aminocycloalkanecarboxamide derivatives are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway.
    Type: Grant
    Filed: February 4, 2003
    Date of Patent: August 15, 2006
    Assignee: Merck & Co., Inc.
    Inventors: Michael R. Wood, Neville J. Anthony, Mark G. Bock, Dong-Mei Feng, Scott D. Kuduk, Dai-Shi Su, Jenny Miu-chun Wai
  • Ketopiperazine derivatives as bradykinin antagonists
    Publication number: 20060178370
    Abstract: Ketopiperazine derivatives are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway.
    Type: Application
    Filed: March 15, 2004
    Publication date: August 10, 2006
    Inventors: Mark Bock, Bruce Dorsey, Dai-Shi Su, Wei Han, Michael Wood
  • 2-(Bicyclo)alkylamino-derivatives as mediators of chronic pain and inflammation
    Publication number: 20060173023
    Abstract: Compounds disclosed herein are bradykinin B1 antagonist compounds useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway.
    Type: Application
    Filed: January 19, 2006
    Publication date: August 3, 2006
    Inventors: Michael Wood, Dai-Shi Su, Jenny Wai
  • System for catalytic combustion
    Publication number: 20060150635
    Abstract: A system comprising a compressor (10) having an inlet stream (25) and an outlet stream (26), a pre-heater (12) having a process inlet stream (29) and a process outlet stream (31), a catalytic combustor (13) having an inlet stream (32) and an outlet stream (33) and containing an catalyst, and a turbine (14) having an inlet stream (34) and an outlet stream (35), wherein, the outlet stream (26) of the compressor(10) is connected to the process inlet stream (29) of the pre-heater (12), the process outlet stream (31) of the pre-heater (12) is connected to the inlet stream (32) of the catalytic combustor (13). The outlet stream (33) of the catalytic combustor (13) is connected to the inlet stream (34) of the turbine (14). During operation of the system, the inlet stream (25) of the compressor (10) has a substantially constant and low concentration of fuel.
    Type: Application
    Filed: September 26, 2003
    Publication date: July 13, 2006
    Inventors: Shi Su, Andrew Beath, Clifford Mallett
  • Arylsulfonamide derivatives
    Publication number: 20060142612
    Abstract: N-aryl arylsulfonamide derivatives are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway.
    Type: Application
    Filed: June 30, 2004
    Publication date: June 29, 2006
    Inventors: Neville Anthony, Jon Lim, Dai-shi Su, Michael Wood
  • Heat engines and associated methods of producing mechanical energy and their application to vehicles
    Patent number: 7062914
    Abstract: A closed cycle gas turbine system (40) comprising system comprising a compressor (52) for producing compressed gas, a gas turbine (42) for receiving the compressed gas, a heat storage means (44) having a first heat transfer means and adapted to receive the compressed gas from the compressor (52) and transmit the compressed gas to the gas turbine (42) and a second heat transfer means (46) for receiving exhaust gas from the gas turbine (42) and transmitting it to the compressor (52) and wherein the second heat transfer means (46) is adapted to transfer at least some heat from the exhaust gas prior to it being transferred to the compressor (52).
    Type: Grant
    Filed: May 30, 2001
    Date of Patent: June 20, 2006
    Assignee: Commonwealth Scientific and Industrial Research Organization
    Inventors: Michael Wendt, Shi Su, Patrick J. Glynn
  • Synthesis of epothilones, intermediates thereto, analogues and uses thereof
    Patent number: 6972335
    Abstract: The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention further provides novel compositions based on analogues of the epothilones and methods for the treatment of cancer and cancer which has developed a multidrug-resistant phenotype.
    Type: Grant
    Filed: December 4, 2001
    Date of Patent: December 6, 2005
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Samuel J. Danishefsky, Peter Bertinato, Dai-Shi Su, Dongfang Meng, Ting-Chao Chou, Ted Kamenecka, Erik J Sorensen, Aaron Balog, Kenneth A. Savin
  • 2-(Bicyclo)alkylamino-derivatives as mediatores of chronic pain and inflammation
    Publication number: 20050261327
    Abstract: Compounds disclosed herein are bradykinin B1 antagonist compounds useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway.
    Type: Application
    Filed: May 18, 2005
    Publication date: November 24, 2005
    Inventors: Mark Bock, Scott Kuduk, Dai-Shi Su, Michael Wood
  • Synthesis of epothilones, intermediates thereto and analogues thereof
    Patent number: 6965034
    Abstract: The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof, useful in the treatment of cancer and cancer which has developed a multidrug-resistant phenotype. Also provided are intermediates useful for preparing said epothilones.
    Type: Grant
    Filed: December 23, 2002
    Date of Patent: November 15, 2005
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Samuel J. Danishefsky, Peter Bertinato, Dai-Shi Su, DongFang Meng, Ting-Chao Chou, Ted Kamenecka, Erik J Sorensen, Aaron Balog, Kenneth A. Savin, Scott Kuduk, Christina Harris, Xiu-Guo Zhang, Joseph R. Bertino
  • N-biphenyl(substituted methyl) aminocycloalkane-carboxamide derivatives
    Patent number: 6919343
    Abstract: N-Biphenyl(substituted methyl)aminocycloalkanecarboxamide derivatives are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway.
    Type: Grant
    Filed: January 30, 2003
    Date of Patent: July 19, 2005
    Assignee: Merck & Co., Inc.
    Inventors: Michael R. Wood, Neville J. Anthony, Mark G. Bock, Dong-Mei Feng, Scott D. Kuduk, Dai-Shi Su, Jenny Miu-chun Wai
  • Quinoxalinone derivatives as bradykinin B1 antagonists
    Patent number: 6908921
    Abstract: 2-Quinoxalinone derivatives are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway.
    Type: Grant
    Filed: July 7, 2003
    Date of Patent: June 21, 2005
    Assignee: Merck & Co., Inc.
    Inventors: Dai-Shi Su, Mark G. Bock
  • N-biphenylmethyl aminocycloalkanecarboxamide derivatives
    Publication number: 20050085667
    Abstract: N-Biphenyl(substituted methyl) aminocycloalkanecarboxamide derivatives are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway.
    Type: Application
    Filed: February 4, 2003
    Publication date: April 21, 2005
    Inventors: Michael Wood, Neville Anthony, Mark Bock, Dong-Mei Feng, Scott Kuduk, Dai-Shi Su, Jenny Wai
  • N-biphenylmethyl aminocycloalkanecarboxamide derivatives with a substiituent on the methyl useful as bradykinin antagonists
    Publication number: 20050084463
    Abstract: N-Biphenyl(substituted methyl)aminocycloalkanecarboxamide derivatives are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway.
    Type: Application
    Filed: February 4, 2003
    Publication date: April 21, 2005
    Inventors: Michael Wood, Neville Anthony, Marg Bock, Dong-Mei Feng, Scott Kuduk, Dai-Shi Su, Jenny Wau
  • Process for forming metal damascene structure to prevent dielectric layer peeling
    Publication number: 20050059233
    Abstract: A process for forming a metal damascene structure. First, a cap layer is formed on a first metal layer, and a dielectric layer is formed on the cap layer. Next, the dielectric layer is etched to form a damascene opening. Next, hydrogen-containing plasma, nitrogen-containing plasma, oxygen-containing plasma, or a mixture thereof is used to perform the plasma treatment. Next, a metal is filled in the damascene opening to form a second metal layer. Peeling of the dielectric layer due to remaining impurities is eliminated by the plasma treatment after etching of the damascene opening.
    Type: Application
    Filed: September 12, 2003
    Publication date: March 17, 2005
    Inventors: Ming-Tsong Wang, Di-Shi Su, Chia-Ming Yang, Ching-Ming Tsai
  • Synthesis of epothilones, intermediates thereto, analogues and uses thereof
    Publication number: 20050043376
    Abstract: The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention further provides novel compositions based on analogues of the epothilones and methods for the treatment of cancer and cancer which has developed a multidrug-resistant phenotype.
    Type: Application
    Filed: December 2, 2003
    Publication date: February 24, 2005
    Inventors: Samuel Danishefsky, Peter Bertinato, Dai-Shi Su, Dongfang Meng, Ting-Chao Chou, Ted Kamenecka, Erik Sorensen, Aaron Balog, Kenneth Savin
  • Synthesis of epothilones, intermediates thereto, analogues and uses thereof
    Publication number: 20050033059
    Abstract: The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention further provides novel compositions based on analogues of the epothilones and methods for the treatment of cancer and cancer which has developed a multidrug-resistant phenotype.
    Type: Application
    Filed: December 4, 2001
    Publication date: February 10, 2005
    Inventors: Samuel Danishefsky, Peter Bertinato, Dai-Shi Su, Dang Fang Meng, Ting-Chao Chou, Ted Kamenecka, Erik Sorensen, Aaron Balog, Kenneth Savin
  • Synthesis of epothilones, intermediates thereto, analogues and uses thereof
    Patent number: 6849651
    Abstract: The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention further provides novel compositions based on analogues of the epothilones and methods for the treatment of cancer and cancer which has developed a multidrug-resistant phenotype.
    Type: Grant
    Filed: June 5, 2001
    Date of Patent: February 1, 2005
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Samuel J. Danishefsky, Peter Bertinato, Dai-Shi Su, Dang Fang Meng, Ting-Chao Chou, Ted Kamenecka, Erik J Sorensen, Aaron Balog, Kenneth A Savin