Abstract: A method for forming a three-dimensional memory device includes forming a memory stack structure which has alternately stacked conductive layers and dielectric layers on a substrate, performing a trim-etching process to form a staircase structure on the memory stack structure, wherein a sidewall of the conductive layer of each step of the staircase structure is recessed from a sidewall of the dielectric layer over the conductive layer to form a recess that exposes a bottom surface of a step nosing portion of the dielectric layer, and forming a plurality of word line contact plugs which respectively extend through one of the dielectric layers of the staircase structure, wherein at least one of the word line contact plugs has a first bottom surface directly contacting a top surface of one of the conductive layers and a second bottom surface directly contacting a top surface of one of the step nosing portions.

Abstract: A polymorphic lithium-silicon compounds for use in pure silicon anode of lithium-ion battery and use thereof are provided. The pure silicon anode includes nucleuses which have one or more structures of Li4.1Si_Cmcm, Li13Si4_Pbam, Li2Si_C12m1, and LiSi_I41/AZ. It was generally believed Li4.1Si_Cmcm to be a high-temperature stable phase, not presenting at room temperature or in the pure silicon anode of lithium-ion battery, but this present invention proves that Li4.1Si_Cmcm can exist in the disclosed material. After lithiation process, the pure silicon anode can have a structure of one or more of Li4.1Si_Cmcm, Li13Si4_Pbam, Li2Si_C12m1, and LiSi_I41/AZ, with extremely improved capacity. The present disclosure may increase the electrical capacity of the pure silicon anode in actual use and solve the problem of the existing pure silicon anode that the volume expansion after repeated lithiation and delithiation leads to electrode damage and battery failure.

Abstract: A circuit includes a first metal layer having a first first metal layer strip adjacent to a first boundary and a second first metal layer strip adjacent to a second boundary opposite to the first boundary. The first and second first metal layer strips, the first boundary, and the second boundary are parallel to each other. The circuit further includes a second metal layer having a first second metal layer strip and a second second metal layer strip adjacent to the first second metal layer strip. The first second metal layer strip is connected to the first metal layer strip at the first first metal layer strip and the second second metal layer strip is connected to the first metal layer strip at the second first metal layer strip. Each of the first and the second second metal layer strips are parallel to each other.

Abstract: The present disclosure provides an anti-Staphylococcus aureus specific antibody and the nucleic acid encoding sequence thereof, and uses of the same. The anti-Staphylococcus aureus specific antibody of the present disclosure achieves the effect of treating Staphylococcus aureus infection and enhancing immune cells against Staphylococcus aureus through various efficacy experiments.

Abstract: A three-dimensional memory device includes a staircase structure comprising steps respectively comprising a conductive layers and a dielectric layer. A sidewall of the conductive layer is recessed from a sidewall of the dielectric layer to form a recess that exposes a portion of a bottom surface of the dielectric layer.

Abstract: Methods and apparatus for processing substrates are provided herein. In some embodiments, a process kit for a substrate support includes: an upper edge ring made of quartz and having an upper surface and a lower surface, wherein the upper surface is substantially planar and the lower surface includes a stepped lower surface to define a radially outermost portion and a radially innermost portion of the upper edge ring.

Abstract: A drug carrier with a property of crossing the blood-brain barrier comprises an extracellular vesicle with a human leukocyte antigen-G antibody on its surface. This carrier can serve as a pharmaceutical composition for promoting apoptosis of brain tumor cells, inhibiting growth of brain tumor cells, or reducing expression of O6-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells. These effects contribute to the treatment of glioblastoma multiforme (GBM).

Abstract: The present disclosure provides a fusion protein and the nucleic acid encoding sequence thereof, and uses of the same. The fusion protein of the present disclosure achieves the effect of treating cancer, immunoregulation and activating immune cells through various efficacy experiments.

Abstract: An apparatus includes a data storage disc having a read/write surface, and an arm extending along an arm axis and having a head end that supports a head that is configured to interact with the read/write surface. The apparatus also includes a rail extending along a rail axis that is normal to the arm axis, and a carriage coupled to the arm and movably coupled to the rail. The apparatus further includes a latch mechanism configured to releasably hold the carriage to the rail at a fixed position.

Abstract: A BAG6 specific chimeric antigen receptor, a nucleic acid, a BAG6 specific chimeric antigen receptor expression plasmid, a BAG6 specific chimeric antigen receptor expressing cell, a pharmaceutical composition for treating cancer, and use of the BAG6 specific chimeric antigen receptor expressing cell are provided. The BAG6 specific chimeric antigen receptor specifically binds to BCL2 associated athanogene 6 (BAG6). The nucleic acid encodes the BAG6 specific chimeric antigen receptor. The BAG6 specific chimeric antigen receptor expression plasmid expresses the BAG6 specific chimeric antigen receptor. The BAG6 specific chimeric antigen receptor expressing cell is obtained by transducing the BAG6 specific chimeric antigen receptor into an immune cell. The pharmaceutical composition for treating cancer includes the BAG6 specific chimeric antigen receptor expressing cell and a pharmaceutically acceptable carrier.

Abstract: A linear driving module includes: a control circuit, a dimming module, and a low-dropout regulator. The control circuit generates switch signals in response to a change in a pulsed DC voltage. The dimming module receives the pulsed DC voltage. The dimming module includes dimming units. Light-emitting diode units in the dimming units are in a light-on state or a light-off state. The low-dropout regulator receives an input voltage from the dimming unit, and converts the input voltage into a regulated voltage. The input voltage varies with the number of light-emitting diode units in the light-on state. The input voltage is lower than the pulsed DC voltage, and the regulated voltage is lower than the input voltage.

Abstract: A package substrate is provided, in which a second dielectric layer with a smaller CTE and a third dielectric layer with a larger CTE are formed on two opposite sides of a wiring structure including a first dielectric layer, respectively, so as to avoid too large a difference in CTE of the wiring structure between two sides thereof, thereby preventing warpage from occurring to the package substrate.

Abstract: The present disclosure provides an anti-tumor antigen nanobody that specifically binds to a human leukocyte antigen-G. The present disclosure also provides the nucleic acid sequence of the anti-tumor antigen nanobody, use of the anti-tumor antigen nanobody for treating cancer and immune-related disorders, and a method for detecting expression levels of HLA-G.

Abstract: A linear driving module includes: a control circuit, a dimming module, and a low-dropout regulator. The control circuit generates switch signals in response to a change in a pulsed DC voltage. The dimming module receives the pulsed DC voltage. The dimming module includes dimming units. Light-emitting diode units in the dimming units are in a light-on state or a light-off state. The low-dropout regulator receives an input voltage from the dimming unit, and converts the input voltage into a regulated voltage. The input voltage varies with the number of light-emitting diode units in the light-on state. The input voltage is lower than the pulsed DC voltage, and the regulated voltage is lower than the input voltage.

Abstract: The present invention disclosed a biological detection chip and its application thereof. The biological detection chip includes a plurality of transistors in parallel. Each of the transistors includes a substrate layer, a floating gate, an extending metal connector, an extending gate, and a biological detection layer. The biological detection chip is combined with biological probes after the surface modification process for biological detection. Biological detection includes Porcine Reproductive and Respiratory Syndrome Virus (PRRSV), Porcine Epidemic Diarrhea Virus (PEDV), and Cortisol detection.

Abstract: A blood pressure measuring method includes the following steps: obtaining a plurality of infrared physiological signals from a wrist radial artery of a user by a physiology signal sensor; processing the plurality of infrared physiological signals for obtaining a plurality of single pulse signals by a signal processing mechanism; performing Fourier expansion on each of the plurality of single pulse signals for extracting a characteristic of each of the plurality of single pulse signals; and inputting the characteristic of each of the plurality of single pulse signals to a blood pressure measuring model established by a convolutional neural network for obtaining a systolic blood pressure and a diastolic blood pressure according to the plurality of infrared single pulse signals.

Abstract: The present disclosure provides an anti-T-cell nanobody that specifically binds to CD3 ?. The present disclosure also provides the nucleic acid sequence of the anti-T-cell nanobody, use of the anti-T-cell nanobody for treating cancer, immunoregulation and activating immune cells, and a method for detecting expression levels of CD3 ?.

Abstract: The present disclosure provides an immunomodulation and anti-tumor-related nanobody that specifically binds to a human leukocyte antigen-G, a programmed cell death ligand 1, and CD3 ?. The present disclosure also provides the nucleic acid sequence of the immunomodulation and anti-tumor-related nanobody, and use of the immunomodulation and anti-tumor-related nanobody for treating cancer and immune-related disorders.

Abstract: The present disclosure provides a three-dimensional memory device and a method of fabricating the same, which includes a substrate, and a memory stack structure. The memory stack structure is disposed on the substrate, and includes a plurality of stack units sequentially stacked into a staircase shape, wherein each of the stack units has a stepped slope, the stepped slope of any one of the stack units disposed in a related lower position is less than the stepped slope of another one of the stack units disposed over the one of the stack units. Through this arrangements, the three-dimensional memory device may therefore obtain an optimized structural integrity, as well as improved component efficiency.

Abstract: A method for sterilizing ambient air includes the steps of: a) installing a plasma-based smart window including an atmospheric pressure plasma device which includes first and second transparent flat patterned electrodes sandwiched between a light-transmissive substrate and a light-transmissive cover plate; and b) applying a power supply parameter of a predetermined magnitude between the first and second transparent flat patterned electrodes at ambient temperature and pressure to generate a surface plasma proximate to the light-transmissive substrate or the light-transmissive cover plate so as to inactivate microorganisms in the ambient air.