Abstract: The invention relates to novel intraocular lenses. The lenses are capable of post-operative adjustment of their optical properties, including conversion from single focal lenses to multifocal lenses.

Abstract: The invention relates to a intraocular lens system having a flexible anterior lens accommodation material behind the lens. The accommodation material may comprise of one or more macromers, which, when polymerized, adjust the properties of the accommodation material. The anterior lens is flexible such that the curvature of the lens changes during accommodation. The anterior lens may be used alone or in combination with a posterior lens.

Abstract: The present invention relates to a method for creating shaped implants, such as intraocular lenses in vivo, as well as the novel implants themselves. Utilizing the method of the invention, it is possible to create an implant in vivo and to adjust either the physical properties such as refractive index, viscosity, etc., mechanical properties such as modulus, tensile strength, tear, etc., or the shape of the implant by noninvasive means. For example, using the method of the patent it is possible to create an intraocular lens in vivo and then adjust the shape and power of the lens through no invasion means. The novel implants are also addressed in this application.

Abstract: The invention relates to novel optical elements having improved UV protection. The optical element comprises a light adjustable optical element with a UV absorbent layer applied to at least one surface of the optical element. The invention is particularly useful in light adjustable intraocular lenses.

Abstract: The invention relates to a novel method for preparing materials whose properties can be manipulated after fabrication. In this process, a base material is created in a manner that provides spaces or voids which can then be filled with a modifying composition. The method is particularly useful in the manufacture of light adjustable optical elements such as intraocular lenses.

Abstract: The invention relates to a multi-lens intraoccular lens system having an accommodation material between the lenses. The system comprises an posterior lens attached to the posterior surface of the capsular bag and an anterior lens attached to the anterior surface of the capsular bag. The anterior and posterior lenses have different optical properties providing different degrees and types of correction. An accommodation material is placed between the anterior and posterior lenses. The accommodation material ma comprise of one or more macromers, which, when polymerized, adjust the properties of the accommodation material.

Abstract: Novel blends of photo-initiators and photo-absorbers are disclosed. By the proper selection of the type and amount of absorber and initiator used in a composition, it is possible to regulate the conditions under which photo-induced reactions occur. In a specific embodiment, blends of UV initiators and photoabsorbers are used to control the conditions under which UV initiated polymerization occurs.

Abstract: The invention relates to novel photoinitiators and their use in light adjustable compositions. The initiatives comprise two or more multiphoton chromophores linked by a bridging compound. The bridging compound consists of a material that is compatible with the base material of the light adjustable composition. The novel photoinitiator permit the readjustment of light adjustable material without the need for significant amounts of photoabsorbers.

Abstract: The invention relates to a novel method for preparing materials whose properties can be manipulated after fabrication. In this process, a base material is created in a manner that provides spaces or voids which can then be filled with a modifying composition. The method is particularly useful in the manufacture of light adjustable optical elements such as intraocular lenses.

Abstract: The invention relates to a novel composition for improving the accommodation capability of an intraocular lens (IOL). In one embodiment, the composition can be injected into the capsular bag where it surrounds an implanted IOL anchoring the IOL to the capsular bag. Alternatively, for anterior chamber IOLs, the composition can be injected into the bag behind the lens. The material has a refractive index similar to that of aqueous thereby reducing any potential interference with the implanted IOL. Accommodation is provided by the mixture of the crosslinked composition caused by the flexing of the muscles. The novel composition is particularly useful in enhancing accommodation for adjustable intraocular lenses.

Abstract: The invention relates to novel intraocular lenses. The lenses are capable of post-operative adjustment of their optical properties, including conversion from single focal lenses to multifocal lenses.

Abstract: The invention relates to novel intraocular lenses. The lenses are capable of post-operative adjustment of their optical properties, including conversion from single focal lenses to multifocal lenses.

Abstract: The invention relates to novel photoinitiators and their use in light adjustable compositions. The initiatives comprise two or more multiphoton chromophores linked by a bridging compound. The bridging compound consists of a material that is compatible with the base material of the light adjustable composition. The novel photoinitiator permit the readjustment of light adjustable material without the need for significant amounts of photoabsorbers.

Abstract: Methods and materials are disclosed for the production of optical elements, in particular intraocular lenses (IOL) that incorporate any amount (0 to 99%) of refraction and/or shape modulating compound into a substantially crosslinked first polymeric matrix. The materials produced according to the inventive methods exhibit certain rheological parameters useful in defining medical lenses. These medical lenses have the ability to change their refractive power via changing the refractive index and/or by altering the shape by stimulus induced polymerization.