Patents by Inventor Shib Sankar Basu

Shib Sankar Basu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11643651
    Abstract: The present invention provides a method of selecting a mRNA for production of a polypeptide of interest comprising: a) producing an array of individual mRNA sequences comprising different nucleotide sequences encoding the polypeptide of interest; b) determining one or more or two or more of the following parameters for each individual mRNA sequence of (a): (i) minimum free energy (MFE) RNA secondary structure; (ii) ensemble free energy (EFE); (iii) frequency of the minimum free energy (FMFE) RNA secondary structure in a thermodynamic ensemble; and (iv) ensemble diversity (ED); c) ranking the individual mRNA sequences of the array according the parameters determined in step (b); and d) selecting a mRNA sequence from the ranked array of step (c), wherein the selected mRNA produces the polypeptide of interest. The present invention further provides a method of selecting a mRNA for enhanced and reduced production of a polypeptide of interest.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: May 9, 2023
    Assignee: Syngenta Participations AG
    Inventors: Shib Sankar Basu, Kristen Kamerath Dang, Thomas Z. McNeill, Kasimalai Azhakanandam, Sheng Guo
  • Patent number: 11505803
    Abstract: The present invention relates to methods and compositions for identifying, selecting and/or producing a maize plant or maize plant part having increased yield under non-drought conditions, increased yield stability under drought conditions, and/or increased drought tolerance. A maize plant or maize plant part, including any progeny and/or seeds derived from a maize plant or germplasm identified, selected and/or produced by any of the methods of the present invention is also provided.
    Type: Grant
    Filed: April 20, 2020
    Date of Patent: November 22, 2022
    Assignee: Syngenta Participations AG
    Inventors: Shib Sankar Basu, Michael Mahlon Magwire
  • Publication number: 20200283789
    Abstract: The present invention relates to methods and compositions for identifying, selecting and/or producing a maize plant or maize plant part having increased yield under non-drought conditions, increased yield stability under drought conditions, and/or increased drought tolerance. A maize plant or maize plant part, including any progeny and/or seeds derived from a maize plant or germplasm identified, selected and/or produced by any of the methods of the present invention is also provided.
    Type: Application
    Filed: April 20, 2020
    Publication date: September 10, 2020
    Applicant: SYNGENTA PARTICIPATIONS AG
    Inventors: Shib Sankar Basu, Michael Mahlon Magwire
  • Patent number: 10662436
    Abstract: The present invention relates to methods and compositions for identifying, selecting and/or producing a maize plant or maize plant part having increased yield under non-drought conditions, increased yield stability under drought conditions, and/or increased drought tolerance. A maize plant or maize plant part, including any progeny and/or seeds derived from a maize plant or germplasm identified, selected and/or produced by any of the methods of the present invention is also provided.
    Type: Grant
    Filed: July 17, 2018
    Date of Patent: May 26, 2020
    Assignee: Syngenta Participation AG
    Inventors: Shib Sankar Basu, Michael Mahlon Magwire
  • Patent number: 10301641
    Abstract: The present invention relates to methods and compositions for identifying, selecting and/or producing a maize plant or maize plant part having increased yield under non-drought conditions, increased yield stability under drought conditions, and/or increased drought tolerance. A maize plant or maize plant part, including any progeny and/or seeds derived from a maize plant or germplasm identified, selected and/or produced by any of the methods of the present invention is also provided.
    Type: Grant
    Filed: June 3, 2016
    Date of Patent: May 28, 2019
    Assignee: Syngenta Participations AG
    Inventors: Shib Sankar Basu, Michael Mahlon Magwire
  • Patent number: 10196669
    Abstract: Methods are disclosed for detecting and measuring polysaccharide-hydrolyzing enzyme activity or concentration by partial hydrolysis using a pre-determined, yet short, incubation time and a pre-determined temperature. The resulting reaction mixture has unique chemical (i.e., reaction products) and physical (i.e., viscosity) properties that can be used to detect or measure the polysaccharide-hydrolyzing enzyme activity or concentration.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: February 5, 2019
    Assignee: Syngenta Participations AG
    Inventors: Tricia Charlene Costello, Shib Sankar Basu, Rogerio T. N. Prata, Hangsik Moon, Xuejun Sean Zhong, Myoung Kim
  • Publication number: 20180312863
    Abstract: The present invention relates to methods and compositions for identifying, selecting and/or producing a maize plant or maize plant part having increased yield under non-drought conditions, increased yield stability under drought conditions, and/or increased drought tolerance. A maize plant or maize plant part, including any progeny and/or seeds derived from a maize plant or germplasm identified, selected and/or produced by any of the methods of the present invention is also provided.
    Type: Application
    Filed: July 17, 2018
    Publication date: November 1, 2018
    Applicant: Syngenta Participations AG
    Inventors: Shib Sankar Basu, Michael Mahlon Magwire
  • Patent number: 10047373
    Abstract: The present invention relates to methods and compositions for identifying, selecting and/or producing a maize plant or maize plant part having increased yield under non-drought conditions, increased yield stability under drought conditions, and/or increased drought tolerance. A maize plant or maize plant part, including any progeny and/or seeds derived from a maize plant or germplasm identified, selected and/or produced by any of the methods of the present invention is also provided.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: August 14, 2018
    Assignee: Syngenta Participations AG
    Inventors: Shib Sankar Basu, Michael Mahlon Magwire
  • Publication number: 20170275641
    Abstract: The present invention relates to compositions and methods for improving yield, yield stability, and/or drought stress tolerance in plants. Plants and/or plant parts identified, selected and/or produced using compositions and methods of the present invention are also provided.
    Type: Application
    Filed: December 17, 2015
    Publication date: September 28, 2017
    Applicant: Syngenta Participations AG
    Inventor: Shib Sankar BASU
  • Publication number: 20170226504
    Abstract: The present invention provides a method of selecting a mRNA for production of a polypeptide of interest comprising: a) producing an array of individual mRNA sequences comprising different nucleotide sequences encoding the polypeptide of interest; b) determining one or more or two or more of the following parameters for each individual mRNA sequence of (a): (i) minimum free energy (MFE) RNA secondary structure; (ii) ensemble free energy (EFE); (iii) frequency of the minimum free energy (FMFE) RNA secondary structure in a thermodynamic ensemble; and (iv) ensemble diversity (ED); c) ranking the individual mRNA sequences of the array according the parameters determined in step (b); and d) selecting a mRNA sequence from the ranked array of step (c), wherein the selected mRNA produces the polypeptide of interest. The present invention further provides a method of selecting a mRNA for enhanced and reduced production of a polypeptide of interest.
    Type: Application
    Filed: February 15, 2017
    Publication date: August 10, 2017
    Applicant: Syngenta Participations AG
    Inventors: Shib Sankar BASU, Kristen Kamerath DANG, Thomas Z. MCNEILL, Kasimalai AZHAKANANDAM, Sheng Guo
  • Publication number: 20170166916
    Abstract: The present invention relates to methods and compositions for identifying, selecting and/or producing a maize plant or maize plant part having increased yield under non-drought conditions, increased yield stability under drought conditions, and/or increased drought tolerance. A maize plant or maize plant part, including any progeny and/or seeds derived from a maize plant or germplasm identified, selected and/or produced by any of the methods of the present invention is also provided.
    Type: Application
    Filed: December 14, 2015
    Publication date: June 15, 2017
    Applicant: Syngenta Participations AG
    Inventors: Shib Sankar Basu, Michael Mahlon Magwire
  • Patent number: 9605258
    Abstract: The present invention provides a method of selecting a mRNA for production of a polypeptide of interest comprising: a) producing an array of individual mRNA sequences comprising different nucleotide sequences encoding the polypeptide of interest; b) determining one or more or two or more of the following parameters for each individual mRNA sequence of (a): (i) minimum free energy (MFE) RNA secondary structure; (ii) ensemble free energy (EFE); (iii) frequency of the minimum free energy (FMFE) RNA secondary structure in a thermodynamic ensemble; and (iv) ensemble diversity (ED); c) ranking the individual mRNA sequences of the array according the parameters determined in step (b); and d) selecting a mRNA sequence from the ranked array of step (c), wherein the selected mRNA produces the polypeptide of interest. The present invention further provides a method of selecting a mRNA for enhanced and reduced production of a polypeptide of interest.
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: March 28, 2017
    Assignee: Syngenta Participations AG
    Inventors: Shib Sankar Basu, Kristen Kamerath Dang, Kasimalai Azhakanandam, Thomas Z. McNeill, Sheng Guo
  • Publication number: 20160348129
    Abstract: The present invention relates to methods and compositions for identifying, selecting and/or producing a maize plant or maize plant part having increased yield under non-drought conditions, increased yield stability under drought conditions, and/or increased drought tolerance. A maize plant or maize plant part, including any progeny and/or seeds derived from a maize plant or germplasm identified, selected and/or produced by any of the methods of the present invention is also provided.
    Type: Application
    Filed: June 3, 2016
    Publication date: December 1, 2016
    Applicant: Syngenta Participations AG
    Inventors: Shib Sankar Basu, Michael Mahlon Magwire
  • Patent number: 9334494
    Abstract: The present invention provides a method of selecting a mRNA for production of a polypeptide of interest comprising: a) producing an array of individual mRNA sequences comprising different nucleotide sequences encoding the polypeptide of interest; b) determining one or more or two or more of the following parameters for each individual mRNA sequence of (a): (i) minimum free energy (MFE) RNA secondary structure; (ii) ensemble free energy (EFE); (iii) frequency of the minimum free energy (FMFE) RNA secondary structure in a thermodynamic ensemble; and (iv) ensemble diversity (ED); c) ranking the individual mRNA sequences of the array according the parameters determined in step (b); and d) selecting a mRNA sequence from the ranked array of step (c), wherein the selected mRNA produces the polypeptide of interest. The present invention further provides a method of selecting a mRNA for enhanced and reduced production of a polypeptide of interest.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: May 10, 2016
    Assignee: SYNGENTA PARTICIPATIONS AG
    Inventors: Shib Sankar Basu, Kristen Kamerath Dang, Kasimalai Azhakanandam, Thomas Z. McNeill, Sheng Guo
  • Publication number: 20150152408
    Abstract: The present invention provides a method of selecting a mRNA for production of a polypeptide of interest comprising: a) producing an array of individual mRNA sequences comprising different nucleotide sequences encoding the polypeptide of interest; b) determining one or more or two or more of the following parameters for each individual mRNA sequence of (a): (i) minimum free energy (MFE) RNA secondary structure; (ii) ensemble free energy (EFE); (iii) frequency of the minimum free energy (FMFE) RNA secondary structure in a thermodynamic ensemble; and (iv) ensemble diversity (ED); c) ranking the individual mRNA sequences of the array according the parameters determined in step (b); and d) selecting a mRNA sequence from the ranked array of step (c), wherein the selected mRNA produces the polypeptide of interest. The present invention further provides a method of selecting a mRNA for enhanced and reduced production of a polypeptide of interest.
    Type: Application
    Filed: January 9, 2015
    Publication date: June 4, 2015
    Inventors: Shib Sankar Basu, Kristen Kamerath Dang, Kasimalai Azhakanandam, Thomas Z. McNeill, Sheng Guo
  • Patent number: 8497127
    Abstract: The invention provides a synthetic phytase polypeptide which encodes an enzymatically susceptible phytase. Also provided are feed or food products comprising an enzymatically susceptible phytase, and transgenic plants which express the enzymatically susceptible phytase. Further provided are methods for making and using enzymatically susceptible phytases, e.g., a method of using an enzymatically susceptible phytase in feed and food processing.
    Type: Grant
    Filed: November 21, 2008
    Date of Patent: July 30, 2013
    Assignee: Syngenta Participations AG
    Inventors: Shib Sankar Basu, Shengsheng Zhang
  • Publication number: 20130084641
    Abstract: The present invention provides a method of selecting a mRNA for production of a polypeptide of interest comprising: a) producing an array of individual mRNA sequences comprising different nucleotide sequences encoding the polypeptide of interest; b) determining one or more or two or more of the following parameters for each individual mRNA sequence of (a): (i) minimum free energy (MFE) RNA secondary structure; (ii) ensemble free energy (EFE); (iii) frequency of the minimum free energy (FMFE) RNA secondary structure in a thermodynamic ensemble; and (iv) ensemble diversity (ED); c) ranking the individual mRNA sequences of the array according the parameters determined in step (b); and d) selecting a mRNA sequence from the ranked array of step (c), wherein the selected mRNA produces the polypeptide of interest. The present invention further provides a method of selecting a mRNA for enhanced and reduced production of a polypeptide of interest.
    Type: Application
    Filed: December 7, 2012
    Publication date: April 4, 2013
    Applicant: Syngenta Participations AG
    Inventors: Shib Sankar Basu, Kristern Kamerath Dang, Kasimalai Azhakanandam, Thomas Z. McNeill, Sheng Guo
  • Patent number: 8409641
    Abstract: The invention provides a synthetic phytase polypeptide which encodes an en/ymatically susceptible phytase. Also provided are feed or food products comprising an enzymatically susceptible phytase, and transgenic plants which express the enzymatically susceptible phytase. Further provided are methods for making and using enzymatically susceptible phytases, e.g., a method of using an enzymatically susceptible phytase in feed and food processing.
    Type: Grant
    Filed: November 21, 2008
    Date of Patent: April 2, 2013
    Assignee: Syngenta Participations AG
    Inventors: Shib Sankar Basu, Shengsheng Zhang
  • Publication number: 20120080590
    Abstract: The present invention relates to methods and systems for identifying seeds that are homozygous for an allele of interest and/or for identifying seeds that are likely to produce plants possessing a desired trait. Methods of producing plants that are homozygous for an allele of interest and/or that possess a desired trait are also provided.
    Type: Application
    Filed: October 4, 2010
    Publication date: April 5, 2012
    Inventor: Shib Sankar Basu
  • Patent number: 8076534
    Abstract: The present invention relates the nucleotide sequence from Chlamydomonas reinhardtii encoding a glucan dikinase enzyme and to methods of use; to modified starch, as well as production and uses thereof. The starch has modified properties of viscosity and a modified phosphate content.
    Type: Grant
    Filed: June 22, 2006
    Date of Patent: December 13, 2011
    Assignee: Syngenta Participations AG
    Inventors: Shib Sankar Basu, Michael B. Lanahan, Mark Kinkema