Patents by Inventor Shib Sankar Basu
Shib Sankar Basu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11643651Abstract: The present invention provides a method of selecting a mRNA for production of a polypeptide of interest comprising: a) producing an array of individual mRNA sequences comprising different nucleotide sequences encoding the polypeptide of interest; b) determining one or more or two or more of the following parameters for each individual mRNA sequence of (a): (i) minimum free energy (MFE) RNA secondary structure; (ii) ensemble free energy (EFE); (iii) frequency of the minimum free energy (FMFE) RNA secondary structure in a thermodynamic ensemble; and (iv) ensemble diversity (ED); c) ranking the individual mRNA sequences of the array according the parameters determined in step (b); and d) selecting a mRNA sequence from the ranked array of step (c), wherein the selected mRNA produces the polypeptide of interest. The present invention further provides a method of selecting a mRNA for enhanced and reduced production of a polypeptide of interest.Type: GrantFiled: February 15, 2017Date of Patent: May 9, 2023Assignee: Syngenta Participations AGInventors: Shib Sankar Basu, Kristen Kamerath Dang, Thomas Z. McNeill, Kasimalai Azhakanandam, Sheng Guo
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Patent number: 11505803Abstract: The present invention relates to methods and compositions for identifying, selecting and/or producing a maize plant or maize plant part having increased yield under non-drought conditions, increased yield stability under drought conditions, and/or increased drought tolerance. A maize plant or maize plant part, including any progeny and/or seeds derived from a maize plant or germplasm identified, selected and/or produced by any of the methods of the present invention is also provided.Type: GrantFiled: April 20, 2020Date of Patent: November 22, 2022Assignee: Syngenta Participations AGInventors: Shib Sankar Basu, Michael Mahlon Magwire
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Publication number: 20200283789Abstract: The present invention relates to methods and compositions for identifying, selecting and/or producing a maize plant or maize plant part having increased yield under non-drought conditions, increased yield stability under drought conditions, and/or increased drought tolerance. A maize plant or maize plant part, including any progeny and/or seeds derived from a maize plant or germplasm identified, selected and/or produced by any of the methods of the present invention is also provided.Type: ApplicationFiled: April 20, 2020Publication date: September 10, 2020Applicant: SYNGENTA PARTICIPATIONS AGInventors: Shib Sankar Basu, Michael Mahlon Magwire
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Patent number: 10662436Abstract: The present invention relates to methods and compositions for identifying, selecting and/or producing a maize plant or maize plant part having increased yield under non-drought conditions, increased yield stability under drought conditions, and/or increased drought tolerance. A maize plant or maize plant part, including any progeny and/or seeds derived from a maize plant or germplasm identified, selected and/or produced by any of the methods of the present invention is also provided.Type: GrantFiled: July 17, 2018Date of Patent: May 26, 2020Assignee: Syngenta Participation AGInventors: Shib Sankar Basu, Michael Mahlon Magwire
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Patent number: 10301641Abstract: The present invention relates to methods and compositions for identifying, selecting and/or producing a maize plant or maize plant part having increased yield under non-drought conditions, increased yield stability under drought conditions, and/or increased drought tolerance. A maize plant or maize plant part, including any progeny and/or seeds derived from a maize plant or germplasm identified, selected and/or produced by any of the methods of the present invention is also provided.Type: GrantFiled: June 3, 2016Date of Patent: May 28, 2019Assignee: Syngenta Participations AGInventors: Shib Sankar Basu, Michael Mahlon Magwire
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Patent number: 10196669Abstract: Methods are disclosed for detecting and measuring polysaccharide-hydrolyzing enzyme activity or concentration by partial hydrolysis using a pre-determined, yet short, incubation time and a pre-determined temperature. The resulting reaction mixture has unique chemical (i.e., reaction products) and physical (i.e., viscosity) properties that can be used to detect or measure the polysaccharide-hydrolyzing enzyme activity or concentration.Type: GrantFiled: May 19, 2017Date of Patent: February 5, 2019Assignee: Syngenta Participations AGInventors: Tricia Charlene Costello, Shib Sankar Basu, Rogerio T. N. Prata, Hangsik Moon, Xuejun Sean Zhong, Myoung Kim
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Publication number: 20180312863Abstract: The present invention relates to methods and compositions for identifying, selecting and/or producing a maize plant or maize plant part having increased yield under non-drought conditions, increased yield stability under drought conditions, and/or increased drought tolerance. A maize plant or maize plant part, including any progeny and/or seeds derived from a maize plant or germplasm identified, selected and/or produced by any of the methods of the present invention is also provided.Type: ApplicationFiled: July 17, 2018Publication date: November 1, 2018Applicant: Syngenta Participations AGInventors: Shib Sankar Basu, Michael Mahlon Magwire
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Patent number: 10047373Abstract: The present invention relates to methods and compositions for identifying, selecting and/or producing a maize plant or maize plant part having increased yield under non-drought conditions, increased yield stability under drought conditions, and/or increased drought tolerance. A maize plant or maize plant part, including any progeny and/or seeds derived from a maize plant or germplasm identified, selected and/or produced by any of the methods of the present invention is also provided.Type: GrantFiled: December 14, 2015Date of Patent: August 14, 2018Assignee: Syngenta Participations AGInventors: Shib Sankar Basu, Michael Mahlon Magwire
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Publication number: 20170275641Abstract: The present invention relates to compositions and methods for improving yield, yield stability, and/or drought stress tolerance in plants. Plants and/or plant parts identified, selected and/or produced using compositions and methods of the present invention are also provided.Type: ApplicationFiled: December 17, 2015Publication date: September 28, 2017Applicant: Syngenta Participations AGInventor: Shib Sankar BASU
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Publication number: 20170226504Abstract: The present invention provides a method of selecting a mRNA for production of a polypeptide of interest comprising: a) producing an array of individual mRNA sequences comprising different nucleotide sequences encoding the polypeptide of interest; b) determining one or more or two or more of the following parameters for each individual mRNA sequence of (a): (i) minimum free energy (MFE) RNA secondary structure; (ii) ensemble free energy (EFE); (iii) frequency of the minimum free energy (FMFE) RNA secondary structure in a thermodynamic ensemble; and (iv) ensemble diversity (ED); c) ranking the individual mRNA sequences of the array according the parameters determined in step (b); and d) selecting a mRNA sequence from the ranked array of step (c), wherein the selected mRNA produces the polypeptide of interest. The present invention further provides a method of selecting a mRNA for enhanced and reduced production of a polypeptide of interest.Type: ApplicationFiled: February 15, 2017Publication date: August 10, 2017Applicant: Syngenta Participations AGInventors: Shib Sankar BASU, Kristen Kamerath DANG, Thomas Z. MCNEILL, Kasimalai AZHAKANANDAM, Sheng Guo
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Publication number: 20170166916Abstract: The present invention relates to methods and compositions for identifying, selecting and/or producing a maize plant or maize plant part having increased yield under non-drought conditions, increased yield stability under drought conditions, and/or increased drought tolerance. A maize plant or maize plant part, including any progeny and/or seeds derived from a maize plant or germplasm identified, selected and/or produced by any of the methods of the present invention is also provided.Type: ApplicationFiled: December 14, 2015Publication date: June 15, 2017Applicant: Syngenta Participations AGInventors: Shib Sankar Basu, Michael Mahlon Magwire
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Patent number: 9605258Abstract: The present invention provides a method of selecting a mRNA for production of a polypeptide of interest comprising: a) producing an array of individual mRNA sequences comprising different nucleotide sequences encoding the polypeptide of interest; b) determining one or more or two or more of the following parameters for each individual mRNA sequence of (a): (i) minimum free energy (MFE) RNA secondary structure; (ii) ensemble free energy (EFE); (iii) frequency of the minimum free energy (FMFE) RNA secondary structure in a thermodynamic ensemble; and (iv) ensemble diversity (ED); c) ranking the individual mRNA sequences of the array according the parameters determined in step (b); and d) selecting a mRNA sequence from the ranked array of step (c), wherein the selected mRNA produces the polypeptide of interest. The present invention further provides a method of selecting a mRNA for enhanced and reduced production of a polypeptide of interest.Type: GrantFiled: January 9, 2015Date of Patent: March 28, 2017Assignee: Syngenta Participations AGInventors: Shib Sankar Basu, Kristen Kamerath Dang, Kasimalai Azhakanandam, Thomas Z. McNeill, Sheng Guo
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Publication number: 20160348129Abstract: The present invention relates to methods and compositions for identifying, selecting and/or producing a maize plant or maize plant part having increased yield under non-drought conditions, increased yield stability under drought conditions, and/or increased drought tolerance. A maize plant or maize plant part, including any progeny and/or seeds derived from a maize plant or germplasm identified, selected and/or produced by any of the methods of the present invention is also provided.Type: ApplicationFiled: June 3, 2016Publication date: December 1, 2016Applicant: Syngenta Participations AGInventors: Shib Sankar Basu, Michael Mahlon Magwire
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Patent number: 9334494Abstract: The present invention provides a method of selecting a mRNA for production of a polypeptide of interest comprising: a) producing an array of individual mRNA sequences comprising different nucleotide sequences encoding the polypeptide of interest; b) determining one or more or two or more of the following parameters for each individual mRNA sequence of (a): (i) minimum free energy (MFE) RNA secondary structure; (ii) ensemble free energy (EFE); (iii) frequency of the minimum free energy (FMFE) RNA secondary structure in a thermodynamic ensemble; and (iv) ensemble diversity (ED); c) ranking the individual mRNA sequences of the array according the parameters determined in step (b); and d) selecting a mRNA sequence from the ranked array of step (c), wherein the selected mRNA produces the polypeptide of interest. The present invention further provides a method of selecting a mRNA for enhanced and reduced production of a polypeptide of interest.Type: GrantFiled: December 7, 2012Date of Patent: May 10, 2016Assignee: SYNGENTA PARTICIPATIONS AGInventors: Shib Sankar Basu, Kristen Kamerath Dang, Kasimalai Azhakanandam, Thomas Z. McNeill, Sheng Guo
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Publication number: 20150152408Abstract: The present invention provides a method of selecting a mRNA for production of a polypeptide of interest comprising: a) producing an array of individual mRNA sequences comprising different nucleotide sequences encoding the polypeptide of interest; b) determining one or more or two or more of the following parameters for each individual mRNA sequence of (a): (i) minimum free energy (MFE) RNA secondary structure; (ii) ensemble free energy (EFE); (iii) frequency of the minimum free energy (FMFE) RNA secondary structure in a thermodynamic ensemble; and (iv) ensemble diversity (ED); c) ranking the individual mRNA sequences of the array according the parameters determined in step (b); and d) selecting a mRNA sequence from the ranked array of step (c), wherein the selected mRNA produces the polypeptide of interest. The present invention further provides a method of selecting a mRNA for enhanced and reduced production of a polypeptide of interest.Type: ApplicationFiled: January 9, 2015Publication date: June 4, 2015Inventors: Shib Sankar Basu, Kristen Kamerath Dang, Kasimalai Azhakanandam, Thomas Z. McNeill, Sheng Guo
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Patent number: 8497127Abstract: The invention provides a synthetic phytase polypeptide which encodes an enzymatically susceptible phytase. Also provided are feed or food products comprising an enzymatically susceptible phytase, and transgenic plants which express the enzymatically susceptible phytase. Further provided are methods for making and using enzymatically susceptible phytases, e.g., a method of using an enzymatically susceptible phytase in feed and food processing.Type: GrantFiled: November 21, 2008Date of Patent: July 30, 2013Assignee: Syngenta Participations AGInventors: Shib Sankar Basu, Shengsheng Zhang
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Publication number: 20130084641Abstract: The present invention provides a method of selecting a mRNA for production of a polypeptide of interest comprising: a) producing an array of individual mRNA sequences comprising different nucleotide sequences encoding the polypeptide of interest; b) determining one or more or two or more of the following parameters for each individual mRNA sequence of (a): (i) minimum free energy (MFE) RNA secondary structure; (ii) ensemble free energy (EFE); (iii) frequency of the minimum free energy (FMFE) RNA secondary structure in a thermodynamic ensemble; and (iv) ensemble diversity (ED); c) ranking the individual mRNA sequences of the array according the parameters determined in step (b); and d) selecting a mRNA sequence from the ranked array of step (c), wherein the selected mRNA produces the polypeptide of interest. The present invention further provides a method of selecting a mRNA for enhanced and reduced production of a polypeptide of interest.Type: ApplicationFiled: December 7, 2012Publication date: April 4, 2013Applicant: Syngenta Participations AGInventors: Shib Sankar Basu, Kristern Kamerath Dang, Kasimalai Azhakanandam, Thomas Z. McNeill, Sheng Guo
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Patent number: 8409641Abstract: The invention provides a synthetic phytase polypeptide which encodes an en/ymatically susceptible phytase. Also provided are feed or food products comprising an enzymatically susceptible phytase, and transgenic plants which express the enzymatically susceptible phytase. Further provided are methods for making and using enzymatically susceptible phytases, e.g., a method of using an enzymatically susceptible phytase in feed and food processing.Type: GrantFiled: November 21, 2008Date of Patent: April 2, 2013Assignee: Syngenta Participations AGInventors: Shib Sankar Basu, Shengsheng Zhang
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Publication number: 20120080590Abstract: The present invention relates to methods and systems for identifying seeds that are homozygous for an allele of interest and/or for identifying seeds that are likely to produce plants possessing a desired trait. Methods of producing plants that are homozygous for an allele of interest and/or that possess a desired trait are also provided.Type: ApplicationFiled: October 4, 2010Publication date: April 5, 2012Inventor: Shib Sankar Basu
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Chlamydomonas glucan dikinase gene, enzyme and modified starch, uses, methods for production thereof
Patent number: 8076534Abstract: The present invention relates the nucleotide sequence from Chlamydomonas reinhardtii encoding a glucan dikinase enzyme and to methods of use; to modified starch, as well as production and uses thereof. The starch has modified properties of viscosity and a modified phosphate content.Type: GrantFiled: June 22, 2006Date of Patent: December 13, 2011Assignee: Syngenta Participations AGInventors: Shib Sankar Basu, Michael B. Lanahan, Mark Kinkema