Patents by Inventor Shigehiko Miyamoto

Shigehiko Miyamoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230400416
    Abstract: Provided is, for example, an automatic determination system. The automatic determination system includes an information storage unit configured to store result-of-detection image information acquired from a chromatographic strip support tool carrying the result-of-detection image information, the result-of-detection image information representing transcribed information regarding expression information obtained on a chromatographic strip that has been through testing, and a result-of-determination deriving unit configured to check an image included in the result-of-detection image information against a data table, and derive a result of determination included in the data table and corresponding to the image.
    Type: Application
    Filed: October 12, 2021
    Publication date: December 14, 2023
    Inventors: Shigehiko MIYAMOTO, Sotaro SANO
  • Publication number: 20230349833
    Abstract: A chromatographic strip support tool (except one that includes a chromatographic strip) is provided. The chromatographic strip support tool includes a support surface that is continuous and on which the chromatographic strip can be placed, a projected portion formed on the support surface and having a first abutting portion that can abut against an extremity of the chromatographic strip placed on the support surface, the extremity being present at one end side of the chromatographic strip, and a display section formed on the support surface and displaying a detection item corresponding to a predetermined location of the chromatographic strip with the chromatographic strip being placed on the support surface in a manner that the extremity of the chromatographic strip abuts against the first abutting portion.
    Type: Application
    Filed: August 11, 2021
    Publication date: November 2, 2023
    Inventors: Sotaro SANO, Shigehiko MIYAMOTO
  • Patent number: 11702650
    Abstract: A test device is provided that can comprise: a housing accommodating a chromatography support, wherein the housing comprises: a supporting part that supports a container accommodating a liquid used for chromatography. A method is provided for performing chromatography using the test device.
    Type: Grant
    Filed: May 8, 2020
    Date of Patent: July 18, 2023
    Assignee: KANEKA CORPORATION
    Inventors: Sotaro Sano, Shigehiko Miyamoto, Takaaki Jikihara
  • Publication number: 20230067733
    Abstract: One or more embodiments of the present invention are intended to dissolve the problem of lowering in reaction efficiency of the nucleic acid amplification reaction using a primer with a polynucleotide tag to prepare an amplified product of a target nucleic acid that can be detected on a solid-phase support.
    Type: Application
    Filed: December 25, 2020
    Publication date: March 2, 2023
    Applicant: KANEKA CORPORATION
    Inventor: Shigehiko MIYAMOTO
  • Patent number: 11274339
    Abstract: A primer set includes a terminal primer A including, in its 3?-terminal part, a nucleotide sequence that hybridizes to a 3?-terminal part of a complementary sequence of a first target nucleic acid sequence, a k-th double-headed primer including two polynucleotides linked at their 5? terminal sides, wherein one of the two polynucleotides includes, in its 3?-terminal part, a nucleotide sequence that hybridizes to a 3?-terminal part of a nucleotide sequence of a k-th target nucleic acid, and the other polynucleotide includes, in its 3?-terminal part, a nucleotide sequence that hybridizes to a 3?-terminal part of a complementary sequence of a (k+1)th target nucleic acid, and a terminal primer B including, in its 3?-terminal part, a nucleotide sequence that hybridizes to a 3?-terminal part of a nucleotide sequence of a N-th target nucleic acid.
    Type: Grant
    Filed: January 2, 2019
    Date of Patent: March 15, 2022
    Assignee: KANEKA CORPORATION
    Inventors: Shigehiko Miyamoto, Takashi Nishizono
  • Patent number: 11154856
    Abstract: A test device includes a housing and a lid. The housing encloses an internal space, has a hole supporting a container accommodating liquid, and includes a perforation/incision part. The lid covers a hole-formed part of the housing. The housing and/or the lid includes a guide that guides the housing and the lid, so that the lid can migrate from the first position to the second position while covering the hole-formed part of the housing. In the first position, the lid covers the hole-formed part of the housing and the container and the container is not incised. During the migration of the lid from the first position to the second position, the container is pushed toward the perforation/incision part by the lid, and the container is incised to leak liquid into the internal space.
    Type: Grant
    Filed: January 28, 2019
    Date of Patent: October 26, 2021
    Assignee: KANEKA CORPORATION
    Inventors: Sotaro Sano, Shigehiko Miyamoto, Takaaki Jikihara
  • Patent number: 10934541
    Abstract: A method for separating a nucleic acid from a specimen includes accommodating a specimen in an accommodation space provided in a nucleic acid-collecting member, transferring a treatment reagent to the nucleic acid-collecting member by connecting a treatment reagent-accommodating container to a treatment reagent-supplying opening of the nucleic acid-collecting member, obtaining a mixture by mixing the specimen and the treatment reagent in a mixing space formed by combining an inner container space of the treatment reagent-accommodating container and the accommodation space of the nucleic acid-collecting member, and pressure-feeding the mixture by reducing a volume of the inner container space of the treatment reagent-accommodating container and discharging the mixture from an mixture-discharging opening of the nucleic acid-collecting member via a carrier that adsorbs the nucleic acid released in the mixture while allowing the mixture to permeate therethrough.
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: March 2, 2021
    Assignee: KANEKA CORPORATION
    Inventors: Motonori Okajima, Takashi Nishizono, Shigehiko Miyamoto, Hozumi Tanaka
  • Patent number: 10837051
    Abstract: A method for producing a dry reagent composition includes preparing a reagent solution including a Good's buffer in a concentration of more than 2.5 mM, an ammonium salt, a drying protection agent, and a nucleic acid amplification enzyme, and drying the reagent solution. A method for suppressing a decrease in enzyme activity during drying includes adding a Good's buffer in a biochemical reagent comprising an ammonium salt and an enzyme prior to drying the enzyme.
    Type: Grant
    Filed: November 8, 2017
    Date of Patent: November 17, 2020
    Assignee: KANEKA CORPORATION
    Inventors: Tatsuya Toga, Shigehiko Miyamoto, Hozumi Tanaka
  • Patent number: 10829805
    Abstract: An object of the invention is to provide a nucleic acid detection method which takes advantage of the high specificity of hybridization techniques, reduces the time length and the number of steps required for detection of PCR products, and allows for easy and highly accurate detection by visual observation without the need of special equipment; and a nucleic acid detection device or kit. The invention provides a method for detecting a target nucleic acid in a sample, which includes performing amplification of the target nucleic acid sequence to synthesize an amplification product having a partially double-stranded structure where a single-stranded region is added to each end of the target sequence, and hybridizing a nucleic acid sequence bound to a development medium and a nucleic acid sequence labeled with a labeling compound with the single-stranded regions of the amplification product to form a sandwich hybridization complex; and a detection device thereof.
    Type: Grant
    Filed: February 2, 2018
    Date of Patent: November 10, 2020
    Assignee: KANEKA CORPORATION
    Inventors: Koji Takahashi, Shigehiko Miyamoto, Takaaki Jikihara, Jun Tomono
  • Publication number: 20200263164
    Abstract: A test device is provided that can comprise: a housing accommodating a chromatography support, wherein the housing comprises: a supporting part that supports a container accommodating a liquid used for chromatography. A method is provided for performing chromatography using the test device.
    Type: Application
    Filed: May 8, 2020
    Publication date: August 20, 2020
    Inventors: Sotaro Sano, Shigehiko Miyamoto, Takaaki Jikihara
  • Patent number: 10392652
    Abstract: Provided is a method for detecting small RNAs in a simple and highly accurate manner. Provided is a nucleic acid detection method including the following steps (a) to (c): (a) carrying out a reverse transcription reaction using a target RNA as a template and a reverse transcription primer having on its 5?-end side a sequence non-complementary to the target RNA to produce a reverse transcription product longer than the target RNA; (b) carrying out a nucleic acid amplification reaction using the reverse transcription product as a template and two primers to produce an amplified double-stranded DNA fragment having a single-stranded region at least at one end; and (c) hybridizing the single-stranded region of the amplified double-stranded DNA fragment to an oligonucleotide probe immobilized on a solid phase.
    Type: Grant
    Filed: November 21, 2014
    Date of Patent: August 27, 2019
    Assignee: KANEKA CORPORATION
    Inventors: Koji Takahashi, Shigehiko Miyamoto, Sotaro Sano, Jun Tomono
  • Publication number: 20190168209
    Abstract: A test device includes a housing and a lid. The housing encloses an internal space, has a hole supporting a container accommodating liquid, and includes a perforation/incision part. The lid covers a hole-formed part of the housing. The housing and/or the lid includes a guide that guides the housing and the lid, so that the lid can migrate from the first position to the second position while covering the hole-formed part of the housing. In the first position, the lid covers the hole-formed part of the housing and the container and the container is not incised. During the migration of the lid from the first position to the second position, the container is pushed toward the perforation/incision part by the lid, and the container is incised to leak liquid into the internal space.
    Type: Application
    Filed: January 28, 2019
    Publication date: June 6, 2019
    Applicant: KANEKA CORPORATION
    Inventors: Sotaro Sano, Shigehiko Miyamoto, Takaaki Jikihara
  • Publication number: 20190119727
    Abstract: A primer set includes a terminal primer A including, in its 3?-terminal part, a nucleotide sequence that hybridizes to a 3?-terminal part of a complementary sequence of a first target nucleic acid sequence, a k-th double-headed primer including two polynucleotides linked at their 5? terminal sides, wherein one of the two polynucleotides includes, in its 3?-terminal part, a nucleotide sequence that hybridizes to a 3?-terminal part of a nucleotide sequence of a k-th target nucleic acid, and the other polynucleotide includes, in its 3?-terminal part, a nucleotide sequence that hybridizes to a 3?-terminal part of a complementary sequence of a (k+1)th target nucleic acid, and a terminal primer B including, in its 3?-terminal part, a nucleotide sequence that hybridizes to a 3?-terminal part of a nucleotide sequence of a N-th target nucleic acid.
    Type: Application
    Filed: January 2, 2019
    Publication date: April 25, 2019
    Applicant: KANEKA CORPORATION
    Inventors: Shigehiko Miyamoto, Takashi Nishizono
  • Patent number: 10073040
    Abstract: A method and a device or kit for detecting a nucleic acid, which enable simple and precise visual detection of a nucleic acid amplified by an nucleic acid amplification method, without necessity of special devices are provided. The method for detecting a nucleic acid in a sample comprises: contacting a sample with a dye to react with each other; and observing a substance produced by the reaction with visible light, and evaluating the presence or absence of a nucleic acid by eye. The device or kit for detecting a nucleic acid in a sample comprises: a carrier that holds a dye which can bind to a nucleic acid; a path for passing a sample through the carrier; and an evaluation part for observing a substance produced by the reaction between the sample and the dye with visible light, and evaluating the presence or absence of a nucleic acid by eye.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: September 11, 2018
    Assignee: KANEKA CORPORATION
    Inventors: Shigehiko Miyamoto, Tomohisa Kato, Koji Takahashi, Jun Tomono
  • Publication number: 20180251835
    Abstract: A nucleic acid detection device includes at least one target detection portion and a control detection portion, wherein a first probe that captures a target nucleic acid is immobilized on the target detection portion, and wherein a second probe that captures a control nucleic acid and a third probe that captures the target nucleic acid are immobilized on the control detection portion.
    Type: Application
    Filed: February 26, 2018
    Publication date: September 6, 2018
    Applicant: Kaneka Corporation
    Inventors: Takashi Nishizono, Sotaro Sano, Shigehiko Miyamoto, Hozumi Tanaka
  • Publication number: 20180201922
    Abstract: A method for separating a nucleic acid from a specimen includes accommodating a specimen in an accommodation space provided in a nucleic acid-collecting member, transferring a treatment reagent to the nucleic acid-collecting member by connecting a treatment reagent-accommodating container to a treatment reagent-supplying opening of the nucleic acid-collecting member, obtaining a mixture by mixing the specimen and the treatment reagent in a mixing space formed by combining an inner container space of the treatment reagent-accommodating container and the accommodation space of the nucleic acid-collecting member, and pressure-feeding the mixture by reducing a volume of the inner container space of the treatment reagent-accommodating container and discharging the mixture from an mixture-discharging opening of the nucleic acid-collecting member via a carrier that adsorbs the nucleic acid released in the mixture while allowing the mixture to permeate therethrough.
    Type: Application
    Filed: March 9, 2018
    Publication date: July 19, 2018
    Applicant: Kaneka Corporation
    Inventors: Motonori Okajima, Takashi Nishizono, Shigehiko Miyamoto, Hozumi Tanaka
  • Publication number: 20180155771
    Abstract: An object of the invention is to provide a nucleic acid detection method which takes advantage of the high specificity of hybridization techniques, reduces the time length and the number of steps required for detection of PCR products, and allows for easy and highly accurate detection by visual observation without the need of special equipment; and a nucleic acid detection device or kit. The invention provides a method for detecting a target nucleic acid in a sample, which includes performing amplification of the target nucleic acid sequence to synthesize an amplification product having a partially double-stranded structure where a single-stranded region is added to each end of the target sequence, and hybridizing a nucleic acid sequence bound to a development medium and a nucleic acid sequence labeled with a labeling compound with the single-stranded regions of the amplification product to form a sandwich hybridization complex; and a detection device thereof.
    Type: Application
    Filed: February 2, 2018
    Publication date: June 7, 2018
    Inventors: Koji TAKAHASHI, Shigehiko Miyamoto, Takaaki Jikihara, Jun Tomono
  • Patent number: 9920356
    Abstract: An object of the invention is to provide a nucleic acid detection method which takes advantage of the high specificity of hybridization techniques, reduces the time length and the number of steps required for detection of PCR products, and allows for easy and highly accurate detection by visual observation without the need of special equipment; and a nucleic acid detection device or kit. The invention provides a method for detecting a target nucleic acid in a sample, which includes performing amplification of the target nucleic acid sequence to synthesize an amplification product having a partially double-stranded structure where a single-stranded region is added to each end of the target sequence, and hybridizing a nucleic acid sequence bound to a development medium and a nucleic acid sequence labeled with a labeling compound with the single-stranded regions of the amplification product to form a sandwich hybridization complex; and a detection device thereof.
    Type: Grant
    Filed: November 24, 2011
    Date of Patent: March 20, 2018
    Assignee: KANEKA CORPORATION
    Inventors: Koji Takahashi, Shigehiko Miyamoto, Takaaki Jikihara, Jun Tomono
  • Publication number: 20180057857
    Abstract: A method for producing a dry reagent composition includes preparing a reagent solution including a Good's buffer in a concentration of more than 2.5 mM, an ammonium salt, a drying protection agent, and a nucleic acid amplification enzyme, and drying the reagent solution. A method for suppressing a decrease in enzyme activity during drying includes adding a Good's buffer in a biochemical reagent comprising an ammonium salt and an enzyme prior to drying the enzyme.
    Type: Application
    Filed: November 8, 2017
    Publication date: March 1, 2018
    Applicant: Kaneka Corporation
    Inventors: Tatsuya Toga, Shigehiko Miyamoto, Hozumi Tanaka
  • Patent number: 9783844
    Abstract: An object of the present invention is to provide methods for amplifying and detecting a nucleic acid that allow efficient hybridization, and devices and kits for use in the methods. The present invention includes amplifying a target nucleic acid into a double-stranded nucleic acid having a single-stranded region at each end, and detecting this nucleic acid. The present invention also provides detection devices and kits that make use of these methods.
    Type: Grant
    Filed: April 26, 2013
    Date of Patent: October 10, 2017
    Assignee: Kaneka Corporation
    Inventors: Koji Takahashi, Shigehiko Miyamoto, Takaaki Jikihara, Sotaro Sano, Jun Tomono