Patents by Inventor Shigehiro Hiki

Shigehiro Hiki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Charge conversional ternary polyplex
    Patent number: 9303122
    Abstract: Disclosed is a polymer composite (polyplex) that contains nucleic acid, a cationic polymer, and an anionic polymer. The anionic polymer covers the surface of the composite comprising the cationic polymer and nucleic acid, has a negative charge at neutral pH, and can change so as to have a positive charge at mildly acidic pH.
    Type: Grant
    Filed: November 17, 2014
    Date of Patent: April 5, 2016
    Assignee: THE UNIVERSITY OF TOKYO
    Inventors: Kazunori Kataoka, Yan Lee, Nobuhiro Nishiyama, Kanjiro Miyata, Makoto Oba, Shigehiro Hiki, Mai Sanjo, HyunJin Kim
  • CHARGE CONVERSIONAL TERNARY POLYPLEX
    Publication number: 20150141575
    Abstract: Disclosed is a polymer composite (polyplex) that contains nucleic acid, a cationic polymer, and an anionic polymer. The anionic polymer covers the surface of the composite comprising the cationic polymer and nucleic acid, has a negative charge at neutral pH, and can change so as to have a positive charge at mildly acidic pH.
    Type: Application
    Filed: November 17, 2014
    Publication date: May 21, 2015
    Applicant: THE UNIVERSITY OF TOKYO
    Inventors: Kazunori KATAOKA, Yan LEE, Nobuhiro NISHIYAMA, Kanjiro MIYATA, Makoto OBA, Shigehiro HIKI, Mai SANJO, HyunJin KIM
  • CHARGE CONVERSIONAL TERNARY POLYPLEX
    Publication number: 20110060123
    Abstract: Disclosed is a polymer composite (polyplex) that contains nucleic acid, a cationic polymer, and an anionic polymer. The anionic polymer covers the surface of the composite comprising the cationic polymer and nucleic acid, has a negative charge at neutral pH, and can change so as to have a positive charge at mildly acidic pH.
    Type: Application
    Filed: April 30, 2009
    Publication date: March 10, 2011
    Inventors: Kazunori Kataoka, Yan Lee, Nobuhiro Nishiyama, Kanjiro Miyata, Makoto Oba, Shigehiro Hiki, Mai Sanjo, HyunJin Kim