Patents by Inventor Shigeki Arawaka

Shigeki Arawaka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Parkinson's Disease-Related Gene GRK5 and Uses Thereof
    Publication number: 20090255001
    Abstract: Large-scale SNP analyses conducted on subjects in a Parkinson's disease patient group and a normal control group led to the successful identification of a gene (GRK5) associated with Parkinson's disease. In addition, it was newly discovered that phosphorylation of ?-synuclein is promoted by enhanced expression of the GRK5 gene, and as a result, the formation of soluble ?-synuclein oligomers is promoted, leading to Parkinson's disease. The present invention enables the assessment of Parkinson's disease as well as the screening of therapeutic agents for Parkinson's disease using as an index the expression of GRK5 gene.
    Type: Application
    Filed: April 18, 2006
    Publication date: October 8, 2009
    Inventors: Takeo Kato, Shigeki Arawaka, Hiroto Matsumine