Abstract: Provided are a hard tissue restoration material, which is excellent in hard tissue restoration ability, extremely effective in promoting recalcification of dental enamel, and excellent in protection properties and aesthetic properties, and a hard tissue restoration method. The hard tissue restoration material according to the present invention is a biocompatible ceramic film with flexibility and pliability that is obtained, for example, by immersing a substrate, having the biocompatible ceramic film formed thereon, in a solvent, which does not dissolve the biocompatible ceramic but dissolves at least a portion of the substrate, to dissolve or separate the substrate. Also, with the hard tissue restoration method according to the present invention, the hard tissue restoration material according to the present invention is bonded to or wound around a hard tissue defect site.

Abstract: Provided are a hard tissue restoration material, which is excellent in hard tissue restoration ability, extremely effective in promoting recalcification of dental enamel, and excellent in protection properties and aesthetic properties, and a hard tissue restoration method. The hard tissue restoration material according to the present invention is a biocompatible ceramic film with flexibility and pliability that is obtained, for example, by immersing a substrate, having the biocompatible ceramic film formed thereon, in a solvent, which does not dissolve the biocompatible ceramic but dissolves at least a portion of the substrate, to dissolve or separate the substrate. Also, with the hard tissue restoration method according to the present invention, the hard tissue restoration material according to the present invention is bonded to or wound around a hard tissue defect site.

Abstract: The present invention provides a flexible, biocompatible transparent sheet (8) which has high biocompatibility and a high ability to adsorb a biologically relevant substance, which can be used as a novel biomaterial, and which can be used to observe the propagation, differentiation, and/or the like of living cells in real time. The biocompatible transparent sheet (8) is produced in such a manner that a biocompatible ceramic film (2) is formed on a substrate (1) soluble in a solvent (11) incapable of dissolving biocompatible ceramics by using exemplary a laser ablation process, the substrate (1) depositing the film (2) is dipped in the solvent (11) and dissolved off, and the isolated film (2) is then dried. The biocompatible transparent sheet (8) is utilizable of producing a flexible cultured cell sheet which can be directly transplanted to an affected area. The cell sheet can be prepared in such a manner that cells are seeded on the biocompatible transparent sheet (8) and then propagated.

Abstract: Disclosed is a detector for chemical sensor devices, the detector being improved in detection sensitivity. Also disclosed is use of such a detector for chemical sensor devices. Specifically, disclosed is a detector for chemical sensor devices by which a substance to be measured is detected by adsorbing the substance contained in a medium on the surface thereof. The detector includes an adsorption layer containing hydroxyapatite or a substituted apatite obtained by substituting a part of elements in hydroxyapatite on a surface which is used for detecting the substance to be measured. Such a detector is greatly improved in detection sensitivity, and thus able to detect a very small amount of a chemical substance.

Abstract: The present invention provides a flexible, biocompatible transparent sheet (8) which has high biocompatibility and a high ability to adsorb a biologically relevant substance, which can be used as a novel biomaterial, and which can be used to observe the propagation, differentiation, and/or the like of living cells in real time. The biocompatible transparent sheet (8) is produced in such a manner that a biocompatible ceramic film (2) is formed on a substrate (1) soluble in a solvent (11) incapable of dissolving biocompatible ceramics by using exemplary a laser ablation process, the substrate (1) depositing the film (2) is dipped in the solvent (11) and dissolved off, and the isolated film (2) is then dried. The biocompatible transparent sheet (8) is utilizable of producing a flexible cultured cell sheet which can be directly transplanted to an affected area. The cell sheet can be prepared in such a manner that cells are seeded on the biocompatible transparent sheet (8) and then propagated.

Abstract: Disclosed is a detector for chemical sensor devices, the detector being improved in detection sensitivity. Also disclosed is use of such a detector for chemical sensor devices. Specifically, disclosed is a detector for chemical sensor devices by which a substance to be measured is detected by adsorbing the substance contained in a medium on the surface thereof. The detector includes an adsorption layer containing hydroxyapatite or a substituted apatite obtained by substituting a part of elements in hydroxyapatite on a surface which is used for detecting the substance to be measured. Such a detector is greatly improved in detection sensitivity, and thus able to detect a very small amount of a chemical substance.