Patents by Inventor Shigenari YAMAGUCHI

Shigenari YAMAGUCHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gene involved in synthesis of cyclic peptide compound, method for producing cyclic peptide compound using the same, and transformant comprising the same
    Patent number: 11946086
    Abstract: This invention is intended to identify a gene cluster involved in biosynthesis of a cyclic peptide compound produced by a filamentous fungus of the Curvularia species and to establish a system for synthesizing such cyclic peptide compound. The gene is composed of a first module to a tenth module and encodes a protein having activity of synthesizing a nonribosomal peptide constituting a basic peptide backbone of a cyclic peptide compound produced by a filamentous fungus of the Curvularia species.
    Type: Grant
    Filed: December 13, 2021
    Date of Patent: April 2, 2024
    Assignees: TOHOKU UNIVERSITY, KUMIAI CHEMICAL INDUSTRY CO., LTD.
    Inventors: Takashi Kubo, Masayuki Machida, Maiko Umemura, Keietsu Abe, Akira Yoshimi, Tomonori Fujioka, Shigenari Yamaguchi, Kiyoshi Kawai
  • Method for producing dihydrotentoxin
    Patent number: 11919928
    Abstract: An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.
    Type: Grant
    Filed: October 12, 2021
    Date of Patent: March 5, 2024
    Assignee: KUMIAI CHEMICAL INDUSTRY CO., LTD.
    Inventors: Takashi Kubo, Masayuki Machida, Tomonori Fujioka, Shigenari Yamaguchi, Kiyoshi Kawai
  • GENE INVOLVED IN SYNTHESIS OF CYCLIC PEPTIDE COMPOUND, METHOD FOR PRODUCING CYCLIC PEPTIDE COMPOUND USING THE SAME, AND TRANSFORMANT COMPRISING THE SAME
    Publication number: 20220259634
    Abstract: This invention is intended to identify a gene cluster involved in biosynthesis of a cyclic peptide compound produced by a filamentous fungus of the Curvularia species and to establish a system for synthesizing such cyclic peptide compound. The gene is composed of a first module to a tenth module and encodes a protein having activity of synthesizing a nonribosomal peptide constituting a basic peptide backbone of a cyclic peptide compound produced by a filamentous fungus of the Curvularia species.
    Type: Application
    Filed: December 13, 2021
    Publication date: August 18, 2022
    Applicants: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, TOHOKU UNIVERSITY, KUMIAI CHEMICAL INDUSTRY CO., LTD.
    Inventors: Takashi KUBO, Masayuki MACHIDA, Maiko UMEMURA, Keietsu ABE, Akira YOSHIMI, Tomonori FUJIOKA, Shigenari YAMAGUCHI, Kiyoshi KAWAI
  • TENTOXIN SYNTHESIS GENE, A METHOD FOR PRODUCING TENTOXIN OR DIHYDROTENTOXIN USING THE SAME, AND A TRANSFORMANT COMPRISING THE SAME
    Publication number: 20220024996
    Abstract: An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.
    Type: Application
    Filed: October 12, 2021
    Publication date: January 27, 2022
    Applicant: KUMIAI CHEMICAL INDUSTRY CO., LTD.
    Inventors: Takashi KUBO, Masayuki MACHIDA, Tomonori FUJIOKA, Shigenari YAMAGUCHI, Kiyoshi KAWAI
  • Gene involved in synthesis of cyclic peptide compound, method for producing cyclic peptide compound using the same, and transformant comprising the same
    Patent number: 11230726
    Abstract: This invention is intended to identify a gene cluster involved in biosynthesis of a cyclic peptide compound produced by a filamentous fungus of the Curvularia species and to establish a system for synthesizing such cyclic peptide compound. The gene is composed of a first module to a tenth module and encodes a protein having activity of synthesizing a nonribosomal peptide constituting a basic peptide backbone of a cyclic peptide compound produced by a filamentous fungus of the Curvularia species.
    Type: Grant
    Filed: December 27, 2017
    Date of Patent: January 25, 2022
    Assignees: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, TOHOKU UNIVERSITY, KUMIAI CHEMICAL INDUSTRY CO., LTD.
    Inventors: Takashi Kubo, Masayuki Machida, Maiko Umemura, Keietsu Abe, Akira Yoshimi, Tomonori Fujioka, Shigenari Yamaguchi, Kiyoshi Kawai
  • Tentoxin synthesis gene, a method for producing tentoxin or dihydrotentoxin using the same, and a transformant comprising the same
    Patent number: 11174297
    Abstract: An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.
    Type: Grant
    Filed: March 16, 2017
    Date of Patent: November 16, 2021
    Assignee: KUMIAI CHEMICAL INDUSTRY CO., LTD.
    Inventors: Takashi Kubo, Masayuki Machida, Tomonori Fujioka, Shigenari Yamaguchi, Kiyoshi Kawai
  • GENE INVOLVED IN SYNTHESIS OF CYCLIC PEPTIDE COMPOUND, METHOD FOR PRODUCING CYCLIC PEPTIDE COMPOUND USING THE SAME, AND TRANSFORMANT COMPRISING THE SAME
    Publication number: 20190316164
    Abstract: This invention is intended to identify a gene cluster involved in biosynthesis of a cyclic peptide compound produced by a filamentous fungus of the Curvularia species and to establish a system for synthesizing such cyclic peptide compound. The gene is composed of a first module to a tenth module and encodes a protein having activity of synthesizing a nonribosomal peptide constituting a basic peptide backbone of a cyclic peptide compound produced by a filamentous fungus of the Curvularia species.
    Type: Application
    Filed: December 27, 2017
    Publication date: October 17, 2019
    Applicants: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, TOHOKU UNIVERSITY, KUMIAI CHEMICAL INDUSTRY CO., LTD.
    Inventors: Takashi KUBO, Masayuki MACHIDA, Maiko UMEMURA, Keietsu ABE, Akira YOSHIMI, Tomonori FUJIOKA, Shigenari YAMAGUCHI, Kiyoshi KAWAI
  • A TENTOXIN SYNTHESIS GENE, A METHOD FOR PRODUCING TENTOXIN OR DIHYDROTENTOXIN USING THE SAME, AND A TRANSFORMANT COMPRISING THE SAME
    Publication number: 20190100565
    Abstract: An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.
    Type: Application
    Filed: March 16, 2017
    Publication date: April 4, 2019
    Applicants: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, KUMIAI CHEMICAL INDUSTRY CO., LTD.
    Inventors: Takashi KUBO, Masayuki MACHIDA, Tomonori FUJIOKA, Shigenari YAMAGUCHI, Kiyoshi KAWAI