Patents by Inventor Shigenori Kotani

Shigenori Kotani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-Acyl-3-[4-(benzoylalkyl)piperazin-1-yl]-sydnonimine compound, process for prodction thereof, and use thereof
    Patent number: 4430342
    Abstract: An N-acyl-3-[4-(benzoylalkyl)piperazin-1-yl]-sydnonimine compound represented by the following formula ##STR1## wherein R.sup.1 represents a hydrogen atom or an alkyl group having 1 to 8 carbon atoms,R.sup.2 represents a lower alkyl group,a lower alkoxy group or a phenyl group, andn represents zero or an integer of 1 to 10,and its acid addition salt. The above sydnonimine compounds are useful for the treatment of troubles of the circulatory system and can be produced by contacting a 3-[4-(benzoylalkyl)-piperazin-1-yl]sydnonimine compound represented by the following formula ##STR2## wherein R.sup.1 and n are as defined, with a carboxylic acid represented by the following formulaR.sup.2 COOHwherein R.sup.2 is as defined.
    Type: Grant
    Filed: September 21, 1982
    Date of Patent: February 7, 1984
    Assignee: Hiroyoshi Hidaka
    Inventors: Hiroyoshi Hidaka, Ikuo Matsumoto, Junji Yoshizawa, Shigenori Kotani
  • Syndonimine derivatives, process for production thereof, and use thereof
    Patent number: 4421754
    Abstract: A 3-[4-(benzoylalkyl)piperazin-1-yl]sydnonimine compound represented by the following formula ##STR1## wherein R represents a hydrogen atom or an alkyl group having 1 to 8 carbon atoms, and n represents zero or an integer of 1 to 10,and its acid addition salt. The above sydnonimine compounds are useful for the treatment of troubles of the circulatory system and can be produced by contacting a 4-(benzoylalkyl)-1-(N-nitrosocyanomethylamino)piperazine represented by the following formula ##STR2## wherein R and n are as defined, with an acid.
    Type: Grant
    Filed: July 29, 1982
    Date of Patent: December 20, 1983
    Assignee: Hiroyoshi Hidaka
    Inventors: Hiroyoshi Hidaka, Ikuo Matsumoto, Junji Yoshizawa, Shigenori Kotani