Abstract: In preparing superfine particle in a reaction chamber by evaporation-in-gas method or on such processes as PVD or CVD using arc- or high-frequency plasma wherein in the proximity of the inner surface of the said reaction chamber, a vessel provided with a number of pores thereon is arranged and gas consisting of given components is introduced into the space between the inner surface of the chamber and the vessel, and spouted through the said pores on the vessel. The resultant superfine particle produced in the chamber and being in Brownian movement or in thermal migration does not adhere to the surface of the vessel by being separated from the vessel by the spouting gas so that the gas containing superfine particle is directed securely to the collecting path, wherein the vessel is made of the material not reactive with the resultant superfines but resistant to heat.

Abstract: Enduracidin is produced by cultivating an enduracidin-producing microorganism, which belongs to the genus Streptomyces and which has enduracidin-excreting ability or m-fluoro-DL-tyrosine-resistance or has these two properties, until enduracidin is substantially accumulated in the culture broth, and then recovering the same.