Patents by Inventor Shigeo Takemura
Shigeo Takemura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 7923025Abstract: The present invention relates to an agent for inhibiting decomposition of a biologically active peptide by a digestive enzyme, which is aminoalkyl methacrylate copolymer E as an effective ingredient, and an agent for reducing viscosity of the gastrointestinal mucosa and mucous layers distributed over this mucosa. The present invention relates to a method for inhibiting decomposition of a biologically active peptide by a digestive enzyme, or a method for reducing viscosity of the gastrointestinal mucosa and/or mucous layers distributed over the mucosa, by administration of aminoalkyl methacrylate copolymer E. Furthermore, the present invention relates to a pharmaceutical composition for oral use with improved absorption, which comprises a biologically active peptide and aminoalkyl methacrylate copolymer E.Type: GrantFiled: January 15, 2003Date of Patent: April 12, 2011Assignee: Astellas Pharma Inc.Inventors: Shunsuke Watanabe, Kiyo Nakanishi, Shigeo Takemura, Yuuki Tsutsui
-
Patent number: 7871644Abstract: The present invention presents a pharmaceutical composition for oral use with improved absorption, which comprises drug, aminoalkyl methacrylate copolymer E, and acidic substance and is obtained by bringing said 3 components together and uniformly mixing at least this polymer and this acidic substance, and a method of improving oral absorption/by using this pharmaceutical composition. Moreover, the present invention presents an agent for improving oral absorption that increases drug permeability of the digestive tract mucous membrane and/or mucous layer present on the surface of this membrane, whose active ingredient is aminoalkyl methacrylate copolymer E. In addition, the present invention presents an oral agent for improving absorption by increasing drug permeability of the digestive tract mucous membrane and/or the mucous layer distributed over this mucous membrane, whose effective component is aminoalkyl methacrylate copolymer E.Type: GrantFiled: September 10, 2004Date of Patent: January 18, 2011Assignee: Astellas Pharma Inc.Inventors: Shunsuke Watanabe, Shigeo Takemura, Yuuki Tsutsui, Himoru Kondo, Kiyo Nakanishi, Kazuhiro Sako, Toyohiro Sawada
-
Publication number: 20100221223Abstract: The present invention proposes a method of inducing both vaccine antigen-specific antibody in blood and vaccine antigen-specific antibody secreted at the mucosal surface using vaccine antigen and adjuvant of said vaccine antigen.Type: ApplicationFiled: May 10, 2010Publication date: September 2, 2010Applicant: Astellas Pharma Inc.Inventors: Yuuki Tsutsui, Kiyo Nakanishi, Shunsuke Watanabe, Shigeo Takemura
-
Patent number: 7008640Abstract: The present invention presents a pharmaceutical composition for oral use with improved absorption, which comprises drug, aminoalkyl methacrylate copolymer E, and acidic substance and is obtained by bringing said 3 components together and uniformly mixing at least this polymer and this acidic substance, and a method of improving oral absorption by using this pharmaceutical composition. Moreover, the present invention presents an agent for improving oral absorption that increases drug permeability of the digestive tract mucous membrane and/or mucous layer present on the surface of this membrane, whose active ingredient is aminoalkyl methacrylate copolymer E. In addition, the present invention presents an oral agent for improving absorption by increasing drug permeability of the digestive tract mucous membrane and/or the mucous layer distributed over this mucous membrane, whose effective component is aminoalkyl methacrylate copolymer E.Type: GrantFiled: July 16, 2001Date of Patent: March 7, 2006Assignee: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Shunsuke Watanabe, Shigeo Takemura, Yuuki Tsutsui, Hiromu Kondo, Kiyo Nakanishi, Kazuhiro Sako, Toyohiro Sawada
-
Publication number: 20050112206Abstract: The present invention presents a pharmaceutical composition for oral use with improved absorption, which comprises drug, aminoalkyl methacrylate copolymer E, and acidic substance and is obtained by bringing said 3 components together and uniformly mixing at least this polymer and this acidic substance, and a method of improving oral absorption/by using this pharmaceutical composition. Moreover, the present invention presents an agent for improving oral absorption that increases drug permeability of the digestive tract mucous membrane and/or mucous layer present on the surface of this membrane, whose active ingredient is aminoalkyl methacrylate copolymer E. In addition, the present invention presents an oral agent for improving absorption by increasing drug permeability of the digestive tract mucous membrane and/or the mucous layer distributed over this mucous membrane, whose effective component is aminoalkyl methacrylate copolymer E.Type: ApplicationFiled: September 10, 2004Publication date: May 26, 2005Applicant: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Shunsuke Watanabe, Shigeo Takemura, Yuuki Tsutsui, Himoru Kondo, Kiyo Nakanishi, Kazuhiro Sako, Toyohiro Sawada
-
Publication number: 20050031587Abstract: The present invention proposes a method of inducing both vaccine antigen-specific antibody in blood and vaccine antigen-specific antibody secreted at the mucosal surface using vaccine antigen and adjuvant of said vaccine antigen.Type: ApplicationFiled: September 29, 2003Publication date: February 10, 2005Applicant: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Yuuki Tsutsui, Kiyo Nakanishi, Shunsuke Watanabe, Shigeo Takemura
-
Publication number: 20030175351Abstract: The present invention relates to an agent for inhibiting decomposition of a biologically active peptide by a digestive enzyme, which is aminoalkyl methacrylate coplolymer E as an effective ingredient, and an agent for reducing viscosity of the gastrointestinal mucosa and mucous layers distributed over this mucosa. The present invention relates to a method for inhibiting decomposition of a biologically active peptide by a digestive enzyme, or a method for reducing viscosity of the gastrointestinal mucosa and/or mucous layers distributed over the mucosa, by administration of aminoalkyl methacrylate copolymer E. Furthermore, the present invention relates to a pharmaceutical composition for oral use with improved absorption, which comprises a biologically active peptide and aminoalkyl methacrylate copolymer E.Type: ApplicationFiled: January 15, 2003Publication date: September 18, 2003Applicant: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Shunsuke Watanabe, Kiyo Nakanishi, Shigeo Takemura, Yuuki Tsutsui
-
Publication number: 20020150624Abstract: The present invention presents a pharmaceutical composition for oral use with improved absorption, which comprises drug, aminoalkyl methacrylate copolymer E, and acidic substance and is obtained by bringing said 3 components together and uniformly mixing at least this polymer and this acidic substance, and a method of improving oral absorption by using this pharmaceutical composition. Moreover, the present invention presents an agent for improving oral absorption that increases drug permeability of the digestive tract mucous membrane and/or mucous layer present on the surface of this membrane, whose active ingredient is aminoalkyl methacrylate copolymer E. In addition, the present invention presents an oral agent for improving absorption by increasing drug permeability of the digestive tract mucous membrane and/or the mucous layer distributed over this mucous membrane, whose effective component is aminoalkyl methacrylate copolymer E.Type: ApplicationFiled: July 16, 2001Publication date: October 17, 2002Inventors: Shunsuke Watanabe, Shigeo Takemura, Yuuki Tsutsui, Hiromu Kondo, Kiyo Nakanishi, Kazuhiro Sako, Toyohiro Sawada
-
Patent number: 5019925Abstract: A magnetic tape recording and reproducing apparatus includes tape leading end and tape trailing end detecting devices, each for detecting transparent and non-transparent portions of a magnetic tape. A control means is provided for activating and deactivating a reel brake in accordance with signals output by the tape leading end and tape trailing end detecting devices. The reel brake is provided for stopping a rotation of a reel which drives the magnetic tape.Type: GrantFiled: March 20, 1990Date of Patent: May 28, 1991Assignee: Matsushita Electric Industrial Co., Ltd.Inventors: Shigeo Takemura, Katsuyuki Taguchi
-
Patent number: 4736145Abstract: Electric control apparatus (20) for equipment (1) comprising a driving circuit (5) for generating a signal (S.sub.1) to drive the equipment as installed in a vehicle, the driving circuit including circuitry having a first specified working voltage range, and a breaking circuit (6) operatively interposed between the driving circuit and the equipment, the breaking circuit including a first switching circuit (100) for operatively interrupting the supply of the drive signal to the equipment under a condition that the supply voltage (Vdd) is lowered below a first predetermined level (V.sub.Type: GrantFiled: October 21, 1986Date of Patent: April 5, 1988Assignee: Honda Giken Kogyo Kabushiki KaishaInventors: Hidetoshi Sakurai, Tomoaki Abe, Shigeo Takemura