Patents by Inventor Shigeomi Watanabe
Shigeomi Watanabe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250000919Abstract: A composition comprising an ingredient that is effective for inducing autophagy in intestinal epithelial cells and intestinal epithelial stem cells and can be ingested at ease on a daily basis is provided. A composition for inducing autophagy, the composition comprising bacterial cells of a lactic acid bacterium belonging to the family Lactobacillaceae is provided. The lactic acid bacterium is preferably a lactic acid bacterium belonging to any of the genera Lactiplantibacillus, Lactobacillus, Lacticaseibacillus, Companilactobacillus, and Limosilactobacillus.Type: ApplicationFiled: July 12, 2022Publication date: January 2, 2025Applicants: National University Corporation Tokyo Medical and Dental University, MEIJI CO., LTD.Inventors: Shigeomi SHMIZU, Yumiko WATANABE, Toshihiro SASHIHARA
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Patent number: 6562756Abstract: There are provided a novel herbicidal composition and method for controlling weeds, the composition comprising the uracil herbicide of Compound A wherein: R1 represents hydrogen or halogen; R2 represents halogen or cyano; R3 represents C1-4 alkyl; R4 represents hydrogen, C1-5 acyl, or benzoyl which may be substituted with R5 which represents one to five substituents selected from the group consisting of halogen, C1-4 alkyl, and C1-4 alkoxy, and at least one compound selected from the group consisting of flurilazole (Compound B), diclonon (Compound C), MON 4660 (Compound D), and benoxacor (Compound E):Type: GrantFiled: March 13, 2002Date of Patent: May 13, 2003Assignee: Nissan Chemical Industries, Ltd.Inventors: Tsutomu Nawamaki, Shigeomi Watanabe, Kunimitsu Nakahira
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Patent number: 5773388Abstract: Novel pyrimidine derivatives of the formula (I): ##STR1## wherein R1 is a C.sub.1 -C.sub.6 haloalkyl group, a C.sub.1 -C.sub.6 alkyl group, a C.sub.3 -C.sub.6 cycloalkyl group or the like, R2 is a hydrogen atom, a C.sub.1 -C.sub.6 alkyl group, a C.sub.3 -C.sub.6 cycloalkyl group or the like, and X is a carbonyl group or --C(R3)OH (wherein R3 is a hydrogen atom, a C.sub.1 -C.sub.6 alkyl group or the like).Type: GrantFiled: February 9, 1996Date of Patent: June 30, 1998Assignee: Nissan Chemical Industries, Ltd.Inventors: Jun Satow, Yasuo Kondo, Yoshihiro Kudo, Takumi Mikashima, Tsutomu Nawamaki, Yoichi Ito, Kazuhisa Sudo, Kunimitsu Nakahira, Shigeomi Watanabe, Kimihiro Ishikawa
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Patent number: 5763365Abstract: A fluoropropylthiazoline represented by the formula (1), a herbicide containing it and intermediates for it.Type: GrantFiled: July 11, 1996Date of Patent: June 9, 1998Assignee: Nissan Chemical Industries, Ltd.Inventors: Kenji Makino, Hideaki Suzuki, Takeshi Nagaoka, Toshio Niki, Yoshiyuki Kusuoka, Toshimasa Hamada, Tsutomu Nawamaki, Shigeomi Watanabe, Yoichi Ito, Kazuhisa Sudo
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Patent number: 5716904Abstract: A novel 4,5-disubstituted pyrimidine derivative of the formula (I): ##STR1## wherein R1 is CF.sub.2 X (X is Cl or Br), R.sub.2 is a C.sub.1 -C.sub.8 alkyl group, a C.sub.3 -C.sub.8 cycloalkyl group, etc., R3 is a halogen atom, SH, NH.sub.2, etc., and R4 is a hydrogen atom, a halogen atom, a C.sub.1 -C.sub.6 alkyl group, etc., is a herbicide having excellent activities.Type: GrantFiled: May 1, 1996Date of Patent: February 10, 1998Assignee: Nissan Chemical Industries, Ltd.Inventors: Jun Satow, Yasuo Kondo, Yoshihiro Kudo, Takumi Mikashima, Tsutomu Nawamaki, Yoichi Ito, Kazuhisa Sudo, Kunimitsu Nakahira, Shigeomi Watanabe, Kimihiro Ishikawa
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Patent number: 5686390Abstract: An iminosulfonylurea compound or a salt thereof which is useful as a herbicide and growth control agent against weeds.Type: GrantFiled: December 15, 1995Date of Patent: November 11, 1997Assignee: Nissan Chemical Industries Ltd.Inventors: Kenzi Makino, Shigeaki Akiyama, Hideaki Suzuki, Takeshi Nagaoka, Toshio Niki, Koichi Suzuki, Tsutomu Nawamaki, Shigeomi Watanabe, Kimihiro Ishikawa
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Patent number: 5604179Abstract: An iminosulfonylurea derivative of the formula (1) or its salt ##STR1## wherein Q is ##STR2## wherein the variables are herein below defined, and a herbicidal and and growth control method.Type: GrantFiled: June 7, 1995Date of Patent: February 18, 1997Assignee: Nissan Chemical Industries Ltd.Inventors: Kenzi Makino, Shigeaki Akiyama, Hideaki Suzuki, Takeshi Nagaoka, Toshio Niki, Koichi Suzuki, Tsutomu Nawamaki, Shigeomi Watanabe, Kimihiro Ishikawa
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Patent number: 5545608Abstract: Pyrazole-glycolic acid amides of the following formula (1) (in which R.sup.1 to R.sup.5 each represent a hydrogen atom or a substituent having a broad definition), and herbicides containing them. The compounds have a high herbicidal effect against paddy weeds, especially Echinochloa crus-galli, while highly safe for paddy rice plants.Type: GrantFiled: April 25, 1994Date of Patent: August 13, 1996Assignee: Nissan Chemical Industries, Ltd.Inventors: Katsushi Morimoto, Masatoshi Ohnari, Tsutomu Nawamaki, Shigeomi Watanabe, Kimihiro Ishikawa
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Patent number: 5518994Abstract: Disclosed are a herbicide and a plant growth regulator comprising a 2-arylaminopyrimidinone derivative represented by the formula (1): ##STR1## (wherein Q represents various kinds of aromatic ring or heterocyclic ring).This compound can be used safely to main crops and shows high herbicidal effect to many weeds with a low dosage, and also shows plant growth regulating effect.Type: GrantFiled: December 6, 1994Date of Patent: May 21, 1996Assignee: Nissan Chemical Industries, Ltd.Inventors: Yasuo Kawamura, Jun Satow, Kenzo Fukuda, Eiichi Oya, Kaoru Itoh, Hiroshi Kita, Hisashi Nakata, Tsutomu Nawamaki, Seiichi Fujii, Shigeomi Watanabe, Kimihiro Ishikawa, Yoichi Ito
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Patent number: 5500406Abstract: The present invention provides novel iminosulfonylurea derivatives which are useful as herbicides with excellent activity and selectivity. These derivatives can be used to protect rice, wheat, corn, soybean, cotton and sugar beet from weeds.Type: GrantFiled: April 15, 1994Date of Patent: March 19, 1996Assignee: Nissan Chemical Industries Ltd.Inventors: Kenzi Makino, Shigeaki Akiyama, Hideaki Suzuki, Takeshi Nagaoka, Toshio Niki, Koichi Suzuki, Tsutomu Nawamaki, Shigeomi Watanabe, Kimihiro Ishikawa
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Patent number: 5356863Abstract: The present invention relates to an uracil derivative represented by the formula (1): ##STR1## in which R.sup.1 represents hydrogen, alkyl or haloalkyl; R.sup.2 represents haloalkyl; R.sup.3 represents hydrogen, alkyl, haloalkyl, hydroxymethyl, halogen or nitro; R.sup.4 represents hydrogen or halogen; R.sup.5 represents hydrogen, halogen, nitro or cyano; X represents oxygen or sulfur: provided that the case where both of Da and Db represent hydrogen is excluded and a herbicide containing the same. The compound can be safely applied to important crops and shows high effect against many weeds in a low amount.Type: GrantFiled: October 21, 1993Date of Patent: October 18, 1994Assignee: Nissan Chemical Industries, Ltd.Inventors: Jun Satow, Kenzou Fukuda, Kaoru Itoh, Hiroshi Kita, Yasuo Kawamura, Koichi Suzuki, Tsutomu Nawamaki, Shigeomi Watanabe, Toshiharu Endo, Kimihiro Ishikawa
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Patent number: 5354731Abstract: A pyridinesulfonamide derivative of the formula (I) and a salt thereof: ##STR1## wherein R.sup.1 is a halogen atom, a trifluoromethyl group, a C.sub.1 -C.sub.6 alkoxycarbonyl group, a C.sub.1 -C.sub.6 mono- or di-alkylaminocarbonyl group, a C.sub.1 -C.sub.6 alkoxy group, a C.sub.1 -C.sub.6 alkylsulfonyl group, a C.sub.1 -C.sub.6 alkylthio group, a C.sub.1 -C.sub.6 alkyl group substituted by a C.sub.1 -C.sub.6 alkoxy group, a C.sub.1 -C.sub.6 alkyl group substituted by a C.sub.1 -C.sub.6 mono- or poly-halogenoalkoxy group, a C.sub.1 -C.sub.6 mono- or poly-halogenoalkoxy group, a C.sub.1 -C.sub.6 mono- or di-alkylaminosulfonyl group, a C.sub.1 -C.sub.6 alkoxyaminosulfonyl group substituted by a C.sub.1 -C.sub.6 alkyl group, a nitro group, a C.sub.1 -C.sub.6 alkyl group substituted by a C.sub.1 -C.sub.6 alkylthio group, a C.sub.1 -C.sub.6 alkyl group substituted by a C.sub.1 -C.sub.6 alkylsulfonyl group, or a C.sub.1 -C.sub.6 alkyl group substituted by a C.sub.1 -C.sub.6 alkoxycarbonyl group;R.sup.Type: GrantFiled: February 11, 1992Date of Patent: October 11, 1994Assignee: Nissan Chemical Industries Ltd.Inventors: Kenzi Makino, Katsushi Morimoto, Shigeaki Akiyama, Hideaki Suzuki, Takeshi Nagaoka, Koichi Suzuki, Tsutomu Nawamaki, Shigeomi Watanabe
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Patent number: 5175299Abstract: A pyrazole derivative having the formula ##STR1## is disclosed; the groups A, B, Q, V, W, X, Y, and Z are defined in the description.Type: GrantFiled: November 1, 1991Date of Patent: December 29, 1992Assignee: Nissan Chemical Industries, Ltd.Inventors: Masatoshi Baba, Takuya Kakuta, Norio Tanaka, Eiichi Oya, Takashi Ikai, Tsutomu Nawamaki, Shigeomi Watanabe
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Patent number: 5154755Abstract: Disclosed herein is uracil derivatives having a trifluoromethyl group at the 6-position and a phenyl group at the 3-position which has a NHSO.sub.2 D.sup.26 group at 5-position of the benzene ring, halogen atom at 4-position thereof and hydrogen atom or halogen atom at 2-position thereof, which are represented by the formula (I) and showing penetrative translocation activity, a very high herbicidal activity and, particularly, no phytotoxicity against soybean, in which as compared with the conventional herbicidal compounds, the said uracil derivatives can be applied for either soil treatment or soil incorporation treatment, thereby producing a quick and high herbicidal effect even at a very low dosage against a large variety of weeds including perennial weeds, and have the property to residual effect for an appropriate period of time.Type: GrantFiled: May 20, 1991Date of Patent: October 13, 1992Assignee: Nissan Chemical Industries Ltd.Inventors: Jun Satow, Kenzou Fukuda, Kaoru Itoh, Koichi Suzuki, Tsutomu Nawamaki, Shigeomi Watanabe
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Patent number: 5152824Abstract: A sulfamidosulfonamide derivative of the formula (1) and an agriculturally suitable salt thereof: ##STR1## wherein Q is ##STR2## X is an oxygen atom or a sulfur atom; and G is ##STR3## which are useful as herbicide.Type: GrantFiled: March 6, 1991Date of Patent: October 6, 1992Assignee: Nissan Chemical Industries Ltd.Inventors: Kenzi Makino, Katsushi Morimoto, Shigeaki Akiyama, Hideaki Suzuki, Takeshi Nagaoka, Koichi Suzuki, Tsutomu Nawamaki, Shigeomi Watanabe
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Patent number: 5145502Abstract: A substituted benzoyl derivative of the formula: ##STR1## ps wherein R is a lower alkyl group, or a phenyl group unsubstituted or substituted by a lower alkyl group, halogen atom or a lower alkoxy group;n is an integer of 2 0r 3;m is an integer of from 0 to 6, and when m is an integer of from 2 to 6, the plurality of R may be the same or different fron one another;l is an integer of 0, 1 or 2;X is a halogen atom, a nitro group, a cyano group, a lower alkyl group, a lower alkoxy group, or a lower haloalkyl group;Y is a hydrogen atom, a halogen atom, a nitro group, a lower alkyl group unsubstituted or substituted by a halogen atom or a lower alkoxy group, a lower alkoxy group, or a lower alkoxy carbonyl group; andZ is a halogen atom, a nitro group, a cyano group, a trifluoromethyl group, a lower alkoxy group, a lower alkylthio group, a lower haloalkylthio group, a lower alkylsulfinyl group, a lower haloalkylsulfinyl group, a lower alkylsulfonyl group, or a lower haloalkylsulfonyl group.Type: GrantFiled: January 14, 1991Date of Patent: September 8, 1992Assignee: Nissan Chemical Industries Ltd.Inventors: Junichi Watanabe, Yasuo Kondo, Masataka Hatanaka, Takashi Ikai, Koichi Suzuki, Tsutomu Nawamaki, Shigeomi Watanabe
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Patent number: 5132434Abstract: A substituted benzoyl derivative of the formula: ##STR1## wherein R is a lower alkyl group, or a phenyl group unsubstituted or substituted by a lower alkyl group, halogen atom or a lower alkoxy group;n is an integer of 2 or 3;m is an integer of from 0 to 6, and when m is an integer of from 2 to 6, the plurality of R may be the same or different from one another;l is an integer of 0, 1 or 2;X is a halogen atom, a nitro group, a cyano group, a lower alkyl group, a lower alkoxy group, or a lower haloalkyl group;Y is a hydrogen atom, a halogen atom, a nitro group, a lower alkyl group unsubstituted or substituted by a halogen atom or a lower alkoxy group, a lower alkoxy group, or a lower alkoxy carbonyl group; andZ is a halogen atom, a nitro group, a cyano group, a trifluoromethyl group, a lower alkoxy group, a lower alkylthio group, a lower haloalkylthio group, a lower alkylsulfinyl group, a lower haloalkylsulfinyl group, a lower alkylsulfonyl group, or a lower haloalkylsulfonyl group.Type: GrantFiled: January 3, 1990Date of Patent: July 21, 1992Assignee: Nissan Chemical Industries Ltd.Inventors: Junichi Watanabe, Yasuo Kondo, Masataka Hatanaka, Takashi Ikai, Koichi Suzuki, Tsutomu Nawamaki, Shigeomi Watanabe
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Patent number: 5127935Abstract: Disclosed herein is uracil derivatives having a haloalkyl group at the 5-position and a phenyl group at the 2-position which has a specific substituent, which are represented by the formula (I) and showing penetrative translocation activity and a very high herbicidal activity, in which as compared with the conventional herbicidal compounds, the said uracil derivatives can be applied for either soil treatment or foliage treatment, thereby producing a quick and high herbicidal effect even at a very low dosage against a large variety of weeds including perennial weeds, and have the property to residual effect for an appropriate period of time.Type: GrantFiled: April 9, 1991Date of Patent: July 7, 1992Assignee: Nissan Chemical Industries Ltd.Inventors: Jun Satow, Kenzou Fukuda, Kaoru Itoh, Koichi Suzuki, Tsutomu Nawamaki, Shigeomi Watanabe
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Patent number: 5116404Abstract: The present invention provides novel uracil derivatives and pesticides which contain the novel uracil derivatives as an active ingredient, and exhibit preventing and controlling effects against harmful living things, especially agricultural insect pests, sanitary insect pests, stored product insect pests, house insect pests and veterinary insect pests at a very low drug-concentration.Type: GrantFiled: January 8, 1991Date of Patent: May 26, 1992Assignee: Nissan Chemical Industries Ltd.Inventors: Shigeru Ishii, Kazunari Nakayama, Kazuo Yagi, Jun Satow, Kenzou Fukuda, Kaoru Itoh, Toshiyuki Umehara, Masaki Kudo, Yoichi Inoue, Tsutomu Nawamaki, Shigeomi Watanabe
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Patent number: RE34779Abstract: A pyrazole derivative of the formula I ##STR1## wherein A is C.sub.1 -C.sub.4 alkyl, C.sub.2 -C.sub.4 alkenyl or C.sub.2 -C.sub.4 alkynyl; B is hydrogen, C.sub.1 -C.sub.3 alkyl, halogen, C.sub.1 -C.sub.3 haloalkyl, C.sub.1 -C.sub.3 alkoxy, C.sub.1 -C.sub.3 alkylthio, C.sub.2 -C.sub.4 alkoxyalkyl, C.sub.2 -C.sub.4 alkylthioalkyl or C.sub.2 -C.sub.4 alkoxycarbonyl; X is C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkoxy, halogen, nitro, cyano, etc.; Y is --OR.sup.1 (wherein R.sup.1 is C.sub.3 -C.sub.8 cycloalkyl, etc), --O--L--O--R.sup.1 (wherein L is C.sub.1 -C.sub.6 alkylene which may be substituted by C.sub.1 -C.sub.3 alkyl), --O--L--OH, --O--L--O--L--O--R.sup.2 (wherein R.sup.2 is hydrogen, C.sub.1 -C.sub.6 alkyl group, etc.), --O--L--R.sup.3 (wherein R.sup.3 is phenyl which may be substituted by C.sub.1 -C.sub.3 alkyl, etc.), --O--M (wherein M is a 3- to 6-membered alicyclic group), --O--L--M, --O--L--NR.sup.4 R.sup.5 (wherein each of R.sup.4 and R.sup.5 is hydrogen or C.sub.1 -C.sub.6 alkyl, or R.sup.Type: GrantFiled: September 18, 1992Date of Patent: November 8, 1994Assignee: Nissan Chemical Industries Ltd.Inventors: Eiichi Oya, Junichi Watanabe, Yasuo Kondo, Takuya Kakuta, Koichi Suzuki, Tsutomu Nawamaki, Shigeomi Watanabe