Abstract: According to one embodiment, a method of generating reference genome data includes: determining, based on a plurality of base sequence data of different subjects, base information relating to at least one position in a base sequence according to a frequency of appearance of each of a plurality of base information at the position. The method further includes generating reference genome data to associate the determined base information with the position.

Abstract: A recording device which backs up a content ? in a recording medium and a recording device which restores the content are registered in a server so as to belong to the same domain group. When the recording device tries to restore the content, the restore is permitted only when both the recording devices belong to the same domain group. When there is a refresh request of the domain group, the domain group is invalidated only when a refresh period has passed. When a refresh number recorded in the recording device is less than or equal to the refresh number recorded in the recording device, the recording device backs up and locally merges the content recorded in the recording device into the recording medium.

Abstract: There is provided a method for preventing the occurrence of abnormal behavior such as cannibalism, fright behavior and collision death during rearing, storage and transportation of tuna of larva, juvenile and young adult fish stages, particularly, of those periods in the seed production. The abnormal behavior during rearing, storage or transportation of tuna is prevented by controlling their visual stimuli, particularly, by making wall and bottom surfaces of a rearing water tank coming with contact with the environment transparent, setting a visual stimulus-buffering material through which light transmits partially in both straight and diagonal directions, maintaining the tuna in the presence of colored fine particles in the environment, or controlling the fluctuation in illumination of the environment, or a combination thereof. Alternatively, death of tuna due to collision with a rearing water tank wall is prevented by stimulating their visual sense.