Patents by Inventor Shigeru Tokita

Shigeru Tokita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7712980
    Abstract: An optical transmission module mounted pluggably to a cage having an opening. The optical transmission module comprises a gasket on at least a part of an outer periphery of the module. The gasket is deformed depending on temperature change. The gasket is deformed according to temperature rise in a direction toward an inner wall of the cage to push the inner wall and deformed according to temperature drop in an opposite direction to the direction.
    Type: Grant
    Filed: April 17, 2008
    Date of Patent: May 11, 2010
    Assignee: Opnext Japan, Inc.
    Inventors: Shigeru Tokita, Hiroo Matsue
  • Patent number: 7645756
    Abstract: The invention provides a compound or its pharmaceutically-acceptable salt of formula wherein A1 is a hydrogen, etc.; j and k are 0 or 1; is a double bond, etc.; is a double bond, etc.; one of W1 and W2 is E—O—W, etc., and the other is a hydrogen atom, etc.; E is a divalent group derived from a benzene ring, etc., by removing two hydrogen atoms therefrom; W is a group of formula (II-1): which has a histamine-H3 receptor antagonistic effect or a histamine-H3 receptor inverse-agonistic effect and is useful for prevention or remedy of metabolic system diseases, circulatory system diseases or nervous system diseases.
    Type: Grant
    Filed: February 17, 2005
    Date of Patent: January 12, 2010
    Assignee: Banyu Pharmaceutical Co. Ltd.
    Inventors: Toshiyuki Takahashi, Akio Kanatani, Shigeru Tokita, Ryo Yoshimoto
  • Patent number: 7643954
    Abstract: A master station includes a group of circuits for performing an optimization method. In such a system, the optimization is achieved by adjusting the pull-up resistance and by setting the best possible clock frequency to ensure that data/clock high and low voltage levels are within predetermined specifications. An optimization procedure is performed in a calibration phase invoked by a user or a system whenever a change is introduced to the system, such as addition or deletion of slave stations, a change of data/clock lines, or a change that may affect on the electrical and timing characteristics of the two-wire communication system.
    Type: Grant
    Filed: May 30, 2007
    Date of Patent: January 5, 2010
    Assignee: Opnext Japan, Inc.
    Inventors: Antony Cleitus, Hiroo Matsue, Tomonao Kikuchi, Shigeru Tokita
  • Publication number: 20090317086
    Abstract: An optical transceiver module for transmitting and receiving an optical signal with a plurality of channels includes timing generator for sequentially generating timing instructions defining different start-up time points, and powering controller for effecting a control such that power supply to at least a portion of circuit components associated with the respective channels is sequentially started in accordance with the timing instructions generated by the timing generator. Current to be instantaneously necessitated when a power switch is turned on or when a power restoration is made from power saving operation modes can be suppressed.
    Type: Application
    Filed: April 25, 2008
    Publication date: December 24, 2009
    Inventors: Naofumi Morohashi, Futoshi Endou, Shigeru Tokita, Hiroo Matsue
  • Publication number: 20090245812
    Abstract: Provided is an optical transmission circuit capable of realizing a high-quality optical signal waveform with low power consumption. An optical transmission circuit (10) includes: a laser diode (800); a modulator (900) for supplying a differential modulation current to an anode terminal and a cathode terminal of the laser diode (800) through transmission lines (301 to 304); a current source (101) for supplying a forward bias current to the laser diode (800); and a magnetic sheet (wave absorber) (400) disposed so as to cover at least a part of the transmission lines (303 and 304). An impedance of the laser diode (800) is lower than characteristic impedances of the transmission lines (301 to 304) which are formed so that the characteristic impedances thereof are matched to an output impedance of the modulator (900).
    Type: Application
    Filed: January 27, 2009
    Publication date: October 1, 2009
    Inventors: Shigeru TOKITA, Hiroo Matsue, Akira Kuwahara
  • Patent number: 7595316
    Abstract: Compound of the formula: (I) [wherein each of X1, X2 and X3 independently represents N or CH, W represents the formula (II):(II) or the formula (III):(III) and Y represents a group of the formula (IV):(IV)], or a pharmacologically acceptable salt thereof. This compound exhibits histamine receptor H3 antagonist or inverse agonist activity and is useful of the treatment and/or prevention of obesity, diabetes, hormonal secretion abnormality, sleep, disorder, etc.
    Type: Grant
    Filed: June 24, 2004
    Date of Patent: September 29, 2009
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Norikazu Ohtake, Akira Naya, Yuji Haga, Makoto Jitsuoka, Takuya Suga, Ryo Yoshimoto, Shigeru Tokita, Akio Kanatani
  • Publication number: 20090209562
    Abstract: The present invention provides a compound represented by formula (I) below, or a pharmaceutically acceptable salt thereof, which, having histamine H3 receptor antagonist or inverse agonist activity, is useful in the prophylaxis or therapy of metabolic diseases, circulatory diseases, or nervous system diseases. [where, for example, Ar is a divalent group formed by eliminating two hydrogen atoms from benzene, X1 is a nitrogen atom, sulfur atom or oxygen atom, R1 is a 5- to 6-membered heteroaryl group, Ring A is a 5- to 6-membered heteroaryl ring, R2 and R3 are amino groups or alkylamino groups, and X2 is represented by formula (II): (where R4 and R5 are lower alkyl groups, and n is an integer from 2 to 4).
    Type: Application
    Filed: February 11, 2009
    Publication date: August 20, 2009
    Applicant: Banyu Pharmaceutical Co., Ltd.
    Inventors: Tsuyoshi Nagase, Nagaaki Sato, Akio Kanatani, Shigeru Tokita
  • Publication number: 20090203710
    Abstract: Provided are a histamine-H3 receptor antagonist; and a preventive and/or a remedy for metabolic system diseases such as obesity, diabetes, hormone secretion disorder, hyperlipemia, gout, fatty liver, circulatory system diseases, for example, stenocardia, acute/congestive cardiac insufficiency, cardiac infarction, coronary arteriosclerosis, hypertension, nephropathy, sleep disorder and various diseases accompanied by sleep disorder such as idiopathic hypersomnia repetitive hypersomnia, true hypersomnia, narcolepsy, sleep periodic acromotion disorder, sleep apnea syndrome, circadian rhythm disorder, chronic fatigue syndrome, REM sleep disorder, senile insomnia, night worker sleep insanitation, idiopathic insomnia, repetitive insomnia, true insomnia, electrolyte metabolism disorder; and central and peripheral nervous system diseases such as bulimia, emotional disorder, melancholia, anxiety, epilepsy, delirium, dementia, shinzophrenia, attention deficit/hyperactivity disorder, memory disorder, Alzheimer's disease
    Type: Application
    Filed: March 6, 2009
    Publication date: August 13, 2009
    Inventors: Norikazu Ohtake, Ryo Yoshimoto, Shigeru Tokita, Akio Kanatani, Sayaka Mizutani
  • Patent number: 7552872
    Abstract: A reader/writer is provided which is capable of speedily recognizing a correspondence between one end and the other end of a fiber-optic cable when a plurality of fiber-optic cables is laid. The reader/writer according to the present invention reads, on receiving through the fiber-optic cable a signal that is an instruction to read data from a RF tag mounted to an end of the fiber-optic cable, data from the RF tag through radio communication, and transmits the read data through the fiber-optic cable. Also, on receiving through the fiber-optic cable a signal that is an instruction to write data into the RF tag and a signal indicating the write data, the reader/writer writes the write instruction and the write data into the RF tag through radio communication.
    Type: Grant
    Filed: February 5, 2007
    Date of Patent: June 30, 2009
    Assignee: Opnext Japan, Inc.
    Inventors: Shigeru Tokita, Hiroo Matsue, Antony Cleitus, Tomonao Kikuchi
  • Patent number: 7547693
    Abstract: Provided are a histamine-H3 receptor antagonist; and a preventive and/or a remedy for metabolic system diseases such as obesity, diabetes, hormone secretion disorder, hyperlipemia, gout, fatty liver, circulatory system diseases, for example, stenocardia, acute/congestive cardiac insufficiency, cardiac infarction, coronary arteriosclerosis, hypertension, nephropathy, sleep disorder and various diseases accompanied by sleep disorder such as idiopathic hypersomnnia, repetitive hypersomnnia, true hypersomnnia, narcolepsy, sleep periodic acromotion disorder, sleep apnea syndrome, circadian rhythm disorder, chronic fatigue syndrome, REM sleep disorder, senile insomnia, night worker sleep insanitation, idiopathic insomnia, repetitive insomnia, true insomnia, electrolyte metabolism disorder, and central and peripheral nervous system diseases such as bulimia, emotional disorder, melancholia, anxiety, epilepsy, delirium, dementia, shinzophrenia, attention deficit/hyperactivity disorder, memory disorder, Alzheimer's dis
    Type: Grant
    Filed: September 21, 2004
    Date of Patent: June 16, 2009
    Assignee: Banyu Pharmaceutical Co. Ltd.
    Inventors: Norikazu Ohtake, Ryo Yoshimoto, Shigeru Tokita, Akio Kanatani, Sayaka Mizutani
  • Publication number: 20090137576
    Abstract: Disclosed is a substance having an antagonistic effect on the binding of histamine to a histamine H3 receptor or an inhibitory effect on the activity which a histamine H3 receptor constantly exhibits. A compound represented by the formula (I) or a pharmaceutically acceptable salt thereof; (I) wherein R1 represents a phenyl group which may be substituted or the like and R2 represents a cyano group which may be substituted or the like, or R1 and R2 together form an aliphatic heterocylic ring which may be substituted; R3 represents a group represented by the formula (II-1) below; and all of X1 to X4 represent a carbon atom or the like: (II-1) where R4 and R5 represent a lower alkyl group or the like; and m1 represents an integer of 2 to 4.
    Type: Application
    Filed: May 29, 2006
    Publication date: May 28, 2009
    Inventors: Shiho Ishikawa, Tsuyoshi Nagase, Nagaaki Sato, Hidekazu Takahashi, Shigeru Tokita, Toshihiro Wada
  • Patent number: 7521455
    Abstract: The present invention provides a compound represented by formula (I) below, or a pharmaceutically acceptable salt thereof, which, having histamine H3 receptor antagonist or inverse agonist activity, is useful in the prophylaxis or therapy of metabolic diseases, circulatory diseases, or nervous system diseases. [where, for example, Ar is a divalent group formed by eliminating two hydrogen atoms from benzene, X1 is a nitrogen atom, sulfur atom or oxygen atom, R1 is a 5- to 6-membered heteroaryl group, Ring A is a 5- to 6-membered heteroaryl ring, R2 and R3 are amino groups or alkylamino groups, and X2 is represented by formula (II): (where R4 and R5 are lower alkyl groups, and n is an integer from 2 to 4).
    Type: Grant
    Filed: February 14, 2005
    Date of Patent: April 21, 2009
    Assignee: Banyu Pharmaceutical Co. Ltd.
    Inventors: Tsuyoshi Nagase, Nagaaki Sato, Akio Kanatani, Shigeru Tokita
  • Publication number: 20090039503
    Abstract: The invention provides a heat radiating structure which reduces a mechanical stress applied to an electronic part mounted on a printed circuit board including a semiconductor package. The heat radiating structure is constructed by a semiconductor package mounted on a printed circuit board, a thermal conduction sheet arranged on an upper surface of the semiconductor package, and a metal case provided with a heat radiating fin for receiving a heat transmitted form the thermal conduction sheet so as to discharge to an atmospheric air, and the metal case is provided with a concavo-convex structure in a contact portion with the thermal conduction sheet.
    Type: Application
    Filed: April 25, 2008
    Publication date: February 12, 2009
    Inventors: Shigeru TOKITA, Hiroo Matsue, Fumihide Maeda
  • Publication number: 20090023163
    Abstract: It is intended to provide a method of measuring an activity, which is a method of measuring an activity of an enzymatic reaction in which a lipid-soluble reaction product is formed by catalyzing an addition reaction of two or more kinds of substrates, characterized by comprising a labeling step in which any one of the substrates is labeled, a reaction step in which an enzymatic reaction is carried out in the presence of an enzyme, all substrates and an acceptor, and a detection step in which the reaction product is detected by bringing the labeled molecule and a molecule to be detected close to each other via the acceptor and transferring an energy generated by the labeled molecule to the molecule to be detected, and a method of evaluating a compound utilizing the method of measuring an activity.
    Type: Application
    Filed: March 29, 2006
    Publication date: January 22, 2009
    Inventors: Shigeru Tokita, Ken Shimamura, Yasuhisa Miyamoto, Hidefumi Kitazawa, Akio Kanatani
  • Publication number: 20090016742
    Abstract: An optical transmission module mounted pluggably to a cage having an opening. The optical transmission module comprises a gasket on at least a part of an outer periphery of the module. The gasket is deformed depending on temperature change. The gasket is deformed according to temperature rise in a direction toward an inner wall of the cage to push the inner wall and deformed according to temperature drop in an opposite direction to the direction.
    Type: Application
    Filed: April 17, 2008
    Publication date: January 15, 2009
    Inventors: Shigeru Tokita, Hiroo Matsue
  • Publication number: 20080275069
    Abstract: This invention provides a compound or its pharmaceutically-acceptable salt of formula (I) wherein R1 represents a lower alkyl group et al; R2 and R3 are same and different and represents hydrogen atm et al; R4 represents the substituent of the formula (I) et al; X1 represents NH, O or S; Y represents N or C; Ar is a divalent substituent derived from aryl et al, by removing two hydrogen atoms therefrom; the ring A represents a 5- or 6-membered heteroaryl group; this compounds has a histamine-H3 receptor antagonistic effect or a histamine-H3 receptor inverse-agonistic effect and is useful for preventive or remedy of metabolic system diseases, circulatory system diseases or nervous system diseases.
    Type: Application
    Filed: May 30, 2005
    Publication date: November 6, 2008
    Inventors: Takashi Mizutani, Tsuyoshi Nagase, Nagaaki Sato, Akio Kanatani, Shigeru Tokita
  • Publication number: 20080269287
    Abstract: Compounds of a formula (I) [wherein, A represents formula (III-1) R3 is a hydrogen, lower alkyl et al; m is 0 or 1; R1 is a hydrogen atom, halogen atom et al, R2 is a hydrogen et al; p is 0 to 4; X is a carbon atom or nitrogen atom; and X1 to X4 is a lower alkyl et al], or pharmaceutical acceptable salts thereof. These have a potency antagonistic to binding to histamine H3 receptor, or have a potency inhibiting the constant activity of histamine H3 receptor, and are useful in the therapy of obesity, diabetes et al.
    Type: Application
    Filed: November 30, 2005
    Publication date: October 30, 2008
    Inventors: Norikazu Ohtake, Takuya Suga, Shigeru Tokita
  • Publication number: 20080171753
    Abstract: A compound represented by, e.g. the formula (I): [wherein X, Y, Z, and W each independently represent optionally substituted methine; A, B, and D each independently represent —C(O)—, etc.; Q represents a methine or a nitrogen; and R represents the formula (II-1), optionally substituted with lower alkyl, etc.; (wherein R6 represents a lower alkyl, etc; and R7 and R8 each independently represents a lower alkyl, etc.)] or a pharmaceutically acceptable salt of the compound. The compounds and salt have antagonistic activity against a histamine H3 receptor or inverse agonistic activity against a histamine H3 receptor. They are useful in the prevention or treatment of metabolic diseases, circulatory diseases, or neurotic diseases.
    Type: Application
    Filed: September 6, 2005
    Publication date: July 17, 2008
    Inventors: Makoto Jitsuoka, Norikazu Ohtake, Nagaaki Sato, Shigeru Tokita, Daisuke Tsukahara
  • Publication number: 20080138089
    Abstract: In an optical transmitter, a light-emitting device, a modulator that outputs a differential modulation current via alternating current coupling capacitors to an anode terminal and a cathode terminal of the light-emitting device, a first current source between the cathode terminal and a ground line (GND) of the light-emitting device, and a second current source between the anode terminal and a power source line (Vcc) of the light-emitting device, are provided.
    Type: Application
    Filed: November 29, 2007
    Publication date: June 12, 2008
    Inventors: Shigeru Tokita, Hiroo Matsue, Antony Cleitus
  • Publication number: 20080139589
    Abstract: A substance that has a potency antagonistic to coupling of histamine with histamine H3 receptor or a potency of inhibiting the constant activity of histamine H3 receptor. There is provided a form I crystal of 2-methyl 3-{4-[3-(1-pyrrolidinyl)propoxy]phenyl}-5-trifluoromethyl-4(3H)-quinazolinone that in the powder X- ray diffractometry, has peaks at 6.4°, 9.7°, 10.2°, 12.9°, 14.2°, 14.7°, 16.0°, 16.3°, 16.8°, 17.6°, 19.5°, 20.3°, 20.6°, 21.2°, 21.8°, 22.1°, 22.4°, 22.6°, 24.0°, 24.3°, 24.9°, 25.7°, 25.9°, 26.5°, 26.7°, 27.4°, 29.1°, 29.4°, 32.3° and 39.0° diffraction angles(2?±0.2°).
    Type: Application
    Filed: February 13, 2006
    Publication date: June 12, 2008
    Inventors: Akio Kanatani, Nagaaki Sato, Tsuyoshi Nagase, Shigeru Tokita