Patents by Inventor Shigetoshi Kashiyama
Shigetoshi Kashiyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6905744Abstract: A multilayered film comprising five layers in which the first, third and fifth layers are made of an ethylene.?-olefin copolymer having a density of 0.930 to 0. 950 g/cm3 and the second and fourth layers are made of a mixed resin comprising 35 to 55% by weight of polypropylene having a density of 0.900 to 0.930 g/cm3, 40 to 60% by weight of ethylene.?-olefin elastomer having a density of 0.860 to 0.900 g/cm3, and 2 to 8% by weight of high-density polyethylene having a density of 0.955 to 0.970 g/cm3; and a container made of the film (bag for infusion fluid, etc.). The multilayered film and the container are useful in medical applications.Type: GrantFiled: December 9, 1999Date of Patent: June 14, 2005Assignee: Otsuka Pharmaceutical Factory, Inc.Inventors: Tamotsu Kataoka, Takayuki Denpou, Motoaki Suzaki, Tatsuya Tanaka, Shigetoshi Kashiyama
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Patent number: 6773775Abstract: A multilayer sealant film for use in the medical field at least comprises as its innermost layer a first layer comprising at least one resin selected from the group consisting of linear low-density polyethylene, low-density polyethylene, polypropylene and polybutene-1, and a third layer comprising an ethylene-vinyl alcohol copolymer and laminated to the outer side of the first layer with a second layer serving as an adhesive layer and comprising a resin containing, as a main component, at least one of an amorphous polyolefin, adherent polyolefin and ethylene-vinyl acetate copolymer. The ethylene-vinyl alcohol copolymer forming the third layer functions as a barrier for preventing contaminants from migrating from outside of the third layer toward the first layer (innermost layer). Further, it is possible to improve the formability of the multilayer film since the difference in density between the resin for forming the first layer and the resin for forming the second layer is set to be 0.02 g/cm3 or less.Type: GrantFiled: December 30, 2002Date of Patent: August 10, 2004Assignee: Otsuka Pharmaceutical Factory, Inc.Inventors: Fujio Inoue, Masamitsu Izumi, Shigetoshi Kashiyama
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Publication number: 20010008686Abstract: A multilayer sealant film for use in the medical field at least comprises as its innermost layer a first layer comprising at least one resin selected from the group consisting of linear low-density polyethylene, low-density polyethylene, polypropylene and polybutene-1, and a third layer comprising an ethylene-vinyl alcohol copolymer and laminated to the outer side of the first layer with a second layer serving as an adhesive layer and comprising a resin containing, as a main component, at least one of an amorphous polyolefin, adherent polyolefin and ethylene-vinyl acetate copolymer. The ethylene-vinyl alcohol copolymer forming the third layer functions as a barrier for preventing contaminants from migrating from outside of the third layer toward the first layer (innermost layer). Further, it is possible to improve the formability of the multilayer film since the difference in density between the resin for forming the first layer and the resin for forming the second layer is set to be 0.02 g/cm3 or less.Type: ApplicationFiled: February 6, 1997Publication date: July 19, 2001Inventors: FUJIO INOUE, MASAMITSU IZUMI, SHIGETOSHI KASHIYAMA
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Patent number: 5811047Abstract: The invention provides a polyolefin drug packaging material characterized in that the content, in the polyolefin, of substances containing 12 to 26 carbon atoms is not more than 150 ppm. The packaging material of the invention is useful because the risk of its reacting with and adversely affecting the drug packaged therewith is minimum.Type: GrantFiled: March 18, 1996Date of Patent: September 22, 1998Assignees: Otsuka Pharmaceutical Factory, Inc., Mitsui Petrochemical Industries, Ltd.Inventors: Fujio Inoue, Masamitsu Izumi, Shigetoshi Kashiyama, Hiroshi Tanaka
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Patent number: 5520975Abstract: A medical multilayer film chiefly for use in forming medical containers having a plurality of chambers comprises an inner layer, an intermediate layer and an outer layer each made primarily of a polyolefin, the inner layer being formed of resin mixture of an ethylene-alpha-olefin copolymer having a density of 0.930 to 0.945 g/cm.sup.3 and a polypropylene, the intermediate layer including at least one resin mixture layer of resin mixture of an ethylene-alpha-lefin copolymer having a density of 0.920 to 0.945 g/cm.sup.3 and an ethylene-alpha-olefin elastomer having a density of 0.880 to 0.890 g/cm.sup.3 in a mixing ratio by weight of 1:5 to 2:1, the resin mixture layer having a thickness of at least 85% of the overall thickness of the intermediate layer, the outer layer being formed of an ethylene-alpha-olefin copolymer having a density of 0.930 to 0.945 g/cm.sup.3.Type: GrantFiled: October 4, 1994Date of Patent: May 28, 1996Assignee: Otsuka Pharmaceutical Factory, Inc.Inventors: Fujio Inoue, Masamitsu Izumi, Shigetoshi Kashiyama
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Patent number: 5501887Abstract: Disclosed is a resin laminate comprising: an outer layer formed from a linear polyethylene having a specific density; an inner layer formed from a linear polyethylene having a specific density; and an intermediate layer(s) provided between the outer layer and the inner layer, wherein at least one intermediate layer comprises a linear polyethylene having a specific density different from those of the linear polyethylenes for forming the outer layer and the inner layer; and at least one layer of the outer, inner and intermediate layers is formed from a linear polyethylene composition containing a high-density polyethylene having a specific density. Also disclosed in a container formed from the resin laminate. The resin laminate is excellent in hygienic qualities, transparency, flexibility and heat resistance. The container is hardly distorted even when subjected to a sterilization process under severe conditions, and is excellent in heat resistance, sealing strength, drop strength, transparency and flexibility.Type: GrantFiled: December 28, 1993Date of Patent: March 26, 1996Assignees: Mitsui Petrochemical Industries, Ltd., Otsuka Pharmaceutical Factory, Inc.Inventors: Hiroshi Tanaka, Kozo Morishige, Katsushi Watanabe, Shigetoshi Kashiyama
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Patent number: 5478617Abstract: A multi-layer film is described having an outer layer containing a linear ethylene-.alpha.-olefin copolymer, an intermediate layer containing a linear ethylene-.alpha.-olefin copolymer, and an inner layer containing a resin in which a predetermined amount of polypropylene is contained in a linear ethylene-.alpha.-olefin copolymer, wherein each component has a predetermined density, respectively, and a predetermined amount of a high-density polyethylene is contained in all layers, and a container using the film. There is no fear of a decrease in sealing strength, deformation, deterioration of transparency, etc., even if sterilization is conducted at a temperature condition of not less than 120.degree. C., and, furthermore, the easy peelable seal part is stable even if the film is molded into a container having a plurality of chambers. Therefore, the resulting container can be suitably used for an infusion bag, etc.Type: GrantFiled: October 4, 1994Date of Patent: December 26, 1995Assignees: Otsuka Pharmaceutical Factory, Inc., Mitsui Petrochemical Industries, Ltd.Inventors: Katsushi Watanabe, Shigetoshi Kashiyama
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Patent number: 5423421Abstract: A container having a plurality of chambers chiefly for use in the field of medicine. The body of the container is made of flexible plastics and has partition means dividing the container body into the chambers and permitting communication between the chambers when required. At least one of the chambers is enclosed with a cover to form a closed space therein around the chamber. The cover is made of a flexible film having barrier properties against moisture and gas. The container is inexpensive, has high quality and is efficient to use and easy to dispose of.Type: GrantFiled: December 28, 1993Date of Patent: June 13, 1995Assignee: Otsuka Pharmaceutical Factory, Inc.Inventors: Fujio Inoue, Masamitsu Izumi, Shigetoshi Kashiyama
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Patent number: 5267646Abstract: A container having a plurality of chambers chiefly for use in the field of medicine. The body of the container is made of flexible plastics and has partition means dividing the container body into the chambers and permitting communication between the chambers when required. The container body comprises container portions forming the plurality of chambers and including at least one container portion having no cover and at least one container portion having a cover. The cover encloses the container portion therewith to form a closed space therein around the container portion and is made of a flexible film having barrier properties against moisture and gas. At least one of a desiccant and an oxygen absorber can accommodated in the closes space. The container is inexpensive, has high quality and is efficient to use and easy to dispose of.Type: GrantFiled: June 30, 1992Date of Patent: December 7, 1993Assignee: Otsuka Pharmaceutical Factory, Inc.Inventors: Fujio Inoue, Yasuo Furuta, Shigetoshi Kashiyama