Patents by Inventor Shigetoshi Okazaki
Shigetoshi Okazaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20230245478Abstract: A discrimination device is a device that discriminates whether or not a discrimination target object is a blood cell based on an image of the discrimination target object, and includes a blood cell feature extraction unit that acquires an image of a blood cell and extracts a feature of the blood cell from the acquired image, a discrimination target object feature extraction unit that acquires the image of the discrimination target object and extracts a feature of the discrimination target object from the acquired image, and a discrimination unit that discriminates whether or not the discrimination target object is a blood cell through anomaly detection based on the extracted feature of the blood cell and the feature of the discrimination target object.Type: ApplicationFiled: June 11, 2021Publication date: August 3, 2023Applicants: HAMAMATSU PHOTONICS K.K., NATIONAL UNIVERSITY CORPORATION HAMAMATSU UNIVERSITY SCHOOL OF MEDICINEInventors: Fumio HASHIMOTO, Kibo OTE, Hidenao YAMADA, Hirotoshi KIKUCHI, Amane HIROTSU, Shigetoshi OKAZAKI
-
Publication number: 20220120660Abstract: A cell observation system observes a cell moving in a flow path with a fluid, and includes a first imaging apparatus, a second imaging apparatus, and a control device. The first imaging apparatus includes a first optical system and a first imaging element, and captures an image of the cell at a first position in a moving direction. The second imaging apparatus includes a second optical system, in which a focus is adjusted based on a focus adjustment signal, and a second imaging element, and captures an image of the cell at a second position downstream of the first position. The control device obtains a passing position of the cell in a cross section of the flow path based on the image obtained by the first imaging element, generates the focus adjustment signal, and provides the signal to the second optical system.Type: ApplicationFiled: February 14, 2020Publication date: April 21, 2022Applicants: NATIONAL UNIVERSITY CORPORATION HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE, HAMAMATSU PHOTONICS K.K.Inventors: Hirotoshi KIKUCHI, Hidenao YAMADA, Amane HIROTSU, Daisuke YAMASHITA, Shigetoshi OKAZAKI
-
Patent number: 11285483Abstract: A cell observation system observes a cell moving in a flow path with a fluid, and includes a first observation apparatus, a second observation apparatus, and a control device. The first observation apparatus includes an objective lens and a line camera. The second observation apparatus includes an objective lens and an area camera. The control device analyzes first imaging data output from the first observation apparatus to determine whether the cell satisfies a specific condition, instructs the area camera to output second imaging data of the cell determined to satisfy the specific condition, and analyzes the second imaging data output from the second observation apparatus to determine whether the cell is a specific cell.Type: GrantFiled: September 5, 2018Date of Patent: March 29, 2022Assignees: HAMAMATSU PHOTONICS K.K., NATIONAL UNIVERSITY CORPORATION HAMAMATSU UNIVERSITY SCHOOL OF MEDICINEInventors: Hirotoshi Kikuchi, Shigetoshi Okazaki, Hidenao Yamada, Yusuke Ozaki, Amane Hirotsu, Daisuke Yamashita
-
Patent number: 10890530Abstract: An image acquisition apparatus includes a spatial light modulator, an optical scanner, a detection unit, a control unit. The spatial light modulator performs focused irradiation on irradiation regions on a surface or inside of an observation object with modulated excitation light. The detection unit has imaging regions in an imaging relation with the irradiation regions on a light receiving surface, each of the imaging regions corresponds to one or two or more pixels, and a pixel that corresponds to none of the imaging regions exists adjacent to each imaging region. The control unit corrects a detection signal of a pixel corresponding to each imaging region on the basis of a detection signal of the pixel that exists adjacent to the imaging region and corresponds to none of the imaging regions, and generates an image of the observation object on the basis of the corrected detection signal.Type: GrantFiled: March 8, 2017Date of Patent: January 12, 2021Assignees: NATIONAL UNIVERSITY CORPORATION HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE, HAMAMATSU PHOTONICS K.K.Inventors: Naoya Matsumoto, Shigetoshi Okazaki
-
Publication number: 20200300762Abstract: An image acquisition apparatus includes a spatial light modulator, an optical scanner, a detection unit, a control unit. The spatial light modulator performs focused irradiation on irradiation regions on a surface or inside of an observation object with modulated excitation light. The detection unit has imaging regions in an imaging relation with the irradiation regions on a light receiving surface, each of the imaging regions corresponds to one or two or more pixels, and a pixel that corresponds to none of the imaging regions exists adjacent to each imaging region. The control unit corrects a detection signal of a pixel corresponding to each imaging region on the basis of a detection signal of the pixel that exists adjacent to the imaging region and corresponds to none of the imaging regions, and generates an image of the observation object on the basis of the corrected detection signal.Type: ApplicationFiled: March 8, 2017Publication date: September 24, 2020Applicants: NATIONAL UNIVERSITY CORPORATION HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE, HAMAMATSU PHOTONICS K.K.Inventors: Naoya MATSUMOTO, Shigetoshi OKAZAKI
-
Publication number: 20190070608Abstract: A cell observation system observes a cell moving in a flow path with a fluid, and includes a first observation apparatus, a second observation apparatus, and a control device. The first observation apparatus includes an objective lens and a line camera. The second observation apparatus includes an objective lens and an area camera. The control device analyzes first imaging data output from the first observation apparatus to determine whether the cell satisfies a specific condition, instructs the area camera to output second imaging data of the cell determined to satisfy the specific condition, and analyzes the second imaging data output from the second observation apparatus to determine whether the cell is a specific cell.Type: ApplicationFiled: September 5, 2018Publication date: March 7, 2019Applicants: HAMAMATSU PHOTONICS K.K., NATIONAL UNIVERSITY CORPORATION HAMAMATSU UNIVERSITY SCHOOL OF MEDICINEInventors: Hirotoshi KIKUCHI, Shigetoshi OKAZAKI, Hidenao YAMADA, Yusuke OZAKI, Amane HIROTSU, Daisuke YAMASHITA
-
Publication number: 20060039520Abstract: The present invention relates to a deuteron generating target having a construction for generating deuteron efficiently, and a deuteron generating target apparatus including the same. The deuteron generating target is constructed by providing an upper film mainly composed of a deuterated organic compound onto a base film mainly composed of a halogen-containing organic compound.Type: ApplicationFiled: December 16, 2003Publication date: February 23, 2006Inventors: Hironori Takahashi, Shigetoshi Okazaki, Shinji Ohsuka
-
Patent number: 6242430Abstract: This invention provides rotaxane type dyes. Specifically, the rotaxane type dye according to the invention has a rotaxane structure which binds dye molecules to both of the termini of a chain group penetrating a cyclodextrin ring, which possesses excellent water-solubility, and which is capable of having a plurality of different dyes.Type: GrantFiled: April 29, 1999Date of Patent: June 5, 2001Assignee: Laboratory of Molecular BiophotonicsInventors: Tomomi Suzuki, Hitoshi Nohta, Shigetoshi Okazaki
-
Patent number: 5905030Abstract: A method and apparatus for measuring enzyme activity by supplying a substrate solution and an enzyme solution into a reaction vessel combined with a total reflection absorption prism is disclosed. A measurement solution (40) in which the enzyme solution and the substrate solution are combined together is kept at a constant temperature within the reaction vessel (26) by a temperature control unit (23), and is stirred by a stirrer (21). Infrared light (36) emitted from an infrared light source (3) is made incident on the interface between a total reflection absorption prism (28) disposed in contact with the measurement solution (40) and the measurement solution (40) from the side of the total reflection absorption prism (28) and is totally reflected by the interface. The spectrum of transmitted infrared light (37) thus totally reflected and emitted is detected by an infrared light detector (5).Type: GrantFiled: June 5, 1998Date of Patent: May 18, 1999Assignee: Laboratory of Molecular BiophotonicsInventors: Shigetoshi Okazaki, Hiroyuki Matsumoto