Patents by Inventor Shigeyuki Ando

Shigeyuki Ando has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polysubstituted thiazolylpyridine carboxyamide antifungal antibiotic
    Patent number: 4956374
    Abstract: Novel antifungal antibiotic compounds have the structural formula ##STR1## A preferred compound where R is 4-hydroxypentyl is denoted BU-3557B.sub.2. A complex of said compounds is produced by fermenting a culture of Sacchrothrix aerocolonigenes strain N806-4 (ATCC 53712). The complex is recovered by adsorption on nonionic porous polymer resin adsorbent and individual component compounds exhibit in vitro activity against fungi and Gram-positive bacteria and BU-3557B.sub.2 demonstrates in vitro antiprotazoal activity. BU-3557B.sub.2 demonstrates in vivo activity against C. albicans vaginal infection and BU-3557A.sub.3 (where R is 1,5-dihydroxy-5,5-dimethylpentyl) demonstrates in vivo activity against C. albicans systemic infection.
    Type: Grant
    Filed: July 29, 1988
    Date of Patent: September 11, 1990
    Assignee: Bristol-Myers Company
    Inventors: Maki Nishio, Shigeyuki Ando, Takeo Miyaki, Masataka Konishi, Toshikazu Oki