Abstract: One embodiment shows a method for producing porous cellulose particles, including: (a) dissolving cellulose diacetate into a solvent to prepare a cellulose diacetate solution; (b) dispersing the cellulose diacetate solution into a medium immiscible with the cellulose diacetate solution to obtain a dispersed system; (c) cooling the dispersed system; (d) adding a poor solvent to the cooled dispersed system to precipitate cellulose diacetate particles; and (e) saponifying the cellulose diacetate particles.

Abstract: A method for preparing a chromatography medium having the properties of high virus adsorption and high fluidity, and a method for producing a virus vaccine using the chromatography medium are provided. The chromatography medium is obtained by forming a sulfated polysaccharide bound with porous particles having an exclusion limit molecular weight of 6000 Da or less when pure water is used as mobile phase and standard polyethylene glycol is used and an average particle size in the range of 30-200 ?m.

Abstract: One embodiment shows a method for producing porous cellulose particles, including: (a) dissolving cellulose diacetate into a solvent to prepare a cellulose diacetate solution; (b) dispersing the cellulose diacetate solution into a medium immiscible with the cellulose diacetate solution to obtain a dispersed system; (c) cooling the dispersed system; (d) adding a poor solvent to the cooled dispersed system to precipitate cellulose diacetate particles; and (e) saponifying the cellulose diacetate particles.

Abstract: A method for preparing a chromatography medium having the properties of high virus adsorption and high fluidity, and a method for producing a virus vaccine using the chromatography medium are provided. The chromatography medium is obtained by forming a sulfated polysaccharide bound with porous particles having an exclusion limit molecular weight of 6000 Da or less when pure water is used as mobile phase and standard polyethylene glycol is used and an average particle size in the range of 30-200 ?m.

Abstract: A Chromatography medium having the properties of high virus adsorption and high fluidity, and a method for producing a virus vaccine using these are provided. The Chromatography medium is formed by binding a sulfated polysaccharide to porous particles having an exclusion limit molecular weight of 6000 Da or less when pure water is used as mobile phase and standard polyethylene glycol is used and an average particle size in the range of 30-200 ?m.

Abstract: A chromatography media having excellent salt tolerance, adsorption characteristics and so forth is provided. The chromatography media contains a base media involving porous particles and polyamine bonded with the base media, in which 20 to 40% of amino groups in the polyamine is modified with a hydrophobic group.

Abstract: A cation exchange chromatography media for purifying of the antibody comprises a base media involving porous particles and a polymer containing, in the range of 30 to 100 mol % based on the total monomer, at least one kind of strong cation exchange monomer unit represented by formula (1) or formula (2), and ion exchange capacity of the cation exchange chromatography media is from 60 to 300 ?mol/mL: (wherein, R1, R2 and R3 are each independently a hydrogen atom or methyl, A1 and A2 are —R4—SO3M, here, R4 is alkylene having 2 to 4 carbons, and M is a hydrogen atom, Na or K.).

Abstract: The present invention provides a chromatography packing material having improved flow rate characteristics and adsorption characteristics. In particular, the present invention provides a chromatography packing material suitable for separation and purification of immunoglobulin in the manufacture of antibody preparations. A porous cellulose gel, which is made by adding polysaccharides having a limiting viscosity of 0.21 to 0.90 dL/g to porous cellulose particles, the dry weight per unit volume of the porous cellulose gel being 1.06 to 1.40 times the dry weight per unit volume of the porous cellulose particles, is used. By adding a predetermined amount of polysaccharides having a predetermined limiting viscosity to porous cellulose particles, flow rate characteristics and adsorption characteristics can be improved.

Abstract: A microorganism culture device comprising a porous matrix layer having a basis weight of 40 to 100 g/m2 and an air permeability of 7 to 24 cm/sec, and at least one layer of a water-soluble polymer layer laminated with the matrix layer.

Abstract: The present invention provides a chromatography packing material having improved flow rate characteristics and adsorption characteristics. In particular, the present invention provides a chromatography packing material suitable for separation and purification of immunoglobulin in the manufacture of antibody preparations. A porous cellulose gel, which is made by adding polysaccharides having a limiting viscosity of 0.21 to 0.90 dL/g to porous cellulose particles, the dry weight per unit volume of the porous cellulose gel being 1.06 to 1.40 times the dry weight per unit volume of the porous cellulose particles, is used. By adding a predetermined amount of polysaccharides having a predetermined limiting viscosity to porous cellulose particles, flow rate characteristics and adsorption characteristics can be improved.

Abstract: The present invention provides a compound selected from sulfated cellulose and salts thereof which can be used as an active ingredient for a cutaneous external preparation produced intending to prevent, soften, improve or cure atopic cutaneous symptoms and the like and which are excellent in a hydrolytic resistance, and dermatitis therapeutic agents and cosmetics using the same.

Abstract: A Chromatography medium having the properties of high virus adsorption and high fluidity, and a method for producing a virus vaccine using these are provided. The Chromatography medium is formed by binding a sulfated polysaccharide to porous particles having an exclusion limit molecular weight of 6000 Da or less when pure water is used as mobile phase and standard polyethylene glycol is used and an average particle size in the range of 30-200 ?m.

Abstract: A microorganism culture device comprising a porous matrix layer having a basis weight of 40 to 100 g/m2 and an air permeability of 7 to 24 cm/sec, and at least one layer of a water-soluble polymer layer laminated with the matrix layer.

Abstract: A microorganism culture device comprising a porous matrix layer having a basis weight of 40 to 100 g/m2 and an air permeability of 7 to 24 cm/sec, and at least one layer of a water-soluble polymer layer laminated with the matrix layer.

Abstract: The present invention provides a compound selected from sulfated cellulose and salts thereof which can be used as an active ingredient for a cutaneous external preparation produced intending to prevent, soften, improve or cure atopic cutaneous symptoms and the like and which are excellent in a hydrolytic resistance, and dermatitis therapeutic agents and cosmetics using the same.

Abstract: A microorganism culture device comprising a porous matrix layer having a basis weight of 40 to 100 g/m2 and an air permeability of 7 to 24 cm/sec, and at least one layer of a water-soluble polymer layer laminated with the matrix layer.

Abstract: A microorganism culture device comprising a porous matrix layer having a basis weight of 40 to 100 g/m2 and an air permeability of 7 to 24 cm/sec, and at least one layer of a water-soluble polymer layer laminated with the matrix layer.

Abstract: A process for producing the protein part of Ca.sup.+2 -binding photoprotein aequorin (apoaequorin) according to a recombinant DNA technique, and a process for purifying the resulting apoaequorin are provided, which production process comprises cultivating a strain having an expression vector piP-HE outside the bacterial bodies transformed into Escherichia coli, followed by separating the resulting culture solution into the bacterial bodies and a culture filtrate, and recovering the culture filtrate, and which purification process comprises adding an acid to the culture filtrate so as to give a pH of 4.7 or less, followed by recovering the resulting white precipitates, dissolving the white precipitates in a buffer solution, reducing the solution, subjecting the resulting apoaequorin fraction to adsorption treatment according to anion exchange chromatography and subjecting the resulting apoaequorin to gel filtration.

Abstract: A multi-purpose laboratory room for mobile applications. The room comprises a housing structure having an airtight laboratory unit and an entrance unit, an air-conditioning and exhausting equipment unit to be installed in the upper part of the housing structure and a drain processing equipment unit to be equipped in the airtight laboratory unit. The clean levels of the laboratory unit and drain processing can be selected in multiple steps by electrical signal control.The laboratory room is composed of the hollow wall structure in the wall, floor and ceiling, in which air pressure in the hollow parts are controlled. The filter is provided with a heating device. In addition, an autoclave automatic sterilizing device is incorporated for processing drain. A suspension type vibration-isolating device is also equipped.

Abstract: An air sterilization filter for the containment of leakage prevention of biologically contaminated air in space for a biotechnological performance, such as a genetic engineering work. The filter comprises a heat durable sheet filter for collecting microorganisms suspended in air and a heater for heating the sheet filter and sterilizing the collected microorganisms. The filter of the invention is also useful for providing a clean room.