Patents by Inventor Shih-Chia Hsiao

Shih-Chia Hsiao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • A NOVEL CD16+ NATURAL KILLER CELL AND A METHOD OF CULTURING CD16+ NATURAL KILLER CELL
    Publication number: 20230036481
    Abstract: The present invention provides a human CD16+ natural killer cell line and a CAR-expressing human CD16+ natural killer cell line. These human CD16+ natural killer cell line and a CAR-expressing human CD16+ natural killer cell line does not include synthetic, genetically modified or purposely deliberately delivered polynucleotide encoding the CD16 receptor and are non-tumorigenic cell lines. Therefore, this human CD16+ natural killer cell line and a CAR-expressing human CD16+ natural killer cell line might provide considerable long-term safety for disease treatment.
    Type: Application
    Filed: January 15, 2021
    Publication date: February 2, 2023
    Applicant: Acepodia Biotechnologies Ltd.
    Inventors: SAI-WEN TANG, ZIH-FEI CHENG, CHIA-YUN LEE, HAO-KANG LI, HSIU-PING YANG, CHING-WEN HSIAO, SEN HEN YANG, TAI-SHENG WU, YAN-LIANG LIN, YAN-DA LAI, SHIH-CHIA HSIAO
  • A NOVEL CD16+ NATURAL KILLER CELL AND A METHOD OF CULTURING CD16+ NATURAL KILLER CELL
    Publication number: 20220073878
    Abstract: The present invention provides a human CD16+ natural killer cell line. This human CD16+ natural killer cell line does not include synthetic, genetically modified or deliberately delivered polynucleotide encoding the CD16 receptor and is a non-tumorigenic cell line. Therefore, this human CD16+ natural killer cell line might provide considerable long-term safety for disease treatment.
    Type: Application
    Filed: January 16, 2020
    Publication date: March 10, 2022
    Applicant: Acepodia Biotechnologies Ltd.
    Inventors: Zih-Fei Cheng, Chia-Yun Lee, Hao-Kang Li, Yan-Liang Lin, Ching-Wen Hsiao, Yan-Da Lai, Yu-Pei Cheng, Hsiu-Ping Yang, Shih-Chia Hsiao
  • DNA-cell conjugates
    Patent number: 9969970
    Abstract: The present invention provides conjugates of DNA and cells by linking the DNA to a native functional group on the cell surface. The cells can be without cell walls or can have cell walls. The modified cells can be linked to a substrate surface and used in assay or bioreactors.
    Type: Grant
    Filed: March 1, 2016
    Date of Patent: May 15, 2018
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Shih-Chia Hsiao, Matthew B. Francis, Carolyn Bertozzi, Richard Mathies, Ravi Chandra, Erik Douglas, Amy Twite, Nicholas Toriello, Hiroaki Onoe
  • DNA-CELL CONJUGATES
    Publication number: 20160319238
    Abstract: The present invention provides conjugates of DNA and cells by linking the DNA to a native functional group on the cell surface. The cells can be without cell walls or can have cell walls. The modified cells can be linked to a substrate surface and used in assay or bioreactors.
    Type: Application
    Filed: March 1, 2016
    Publication date: November 3, 2016
    Inventors: Shih-Chia Hsiao, Matthew B. Francis, Carolyn Bertozzi, Richard Mathies, Ravi Chandra, Erik Douglas, Amy Twite, Nicholas Toriello, Hiroaki Onoe
  • DNA-cell conjugates
    Patent number: 9327036
    Abstract: The present invention provides conjugates of DNA and cells by linking the DNA to a native functional group on the cell surface. The cells can be without cell walls or can have cell walls. The modified cells can be linked to a substrate surface and used in assay or bioreactors.
    Type: Grant
    Filed: April 8, 2010
    Date of Patent: May 3, 2016
    Assignee: The Regents of the University of California
    Inventors: Shih-Chia Hsiao, Matthew B. Francis, Carolyn Bertozzi, Richard Mathies, Ravi Chandra, Erik Douglas, Amy Twite, Nicholas Toriello, Hiroaki Onoe
  • DNA-CELL CONJUGATES
    Publication number: 20120142088
    Abstract: The present invention provides conjugates of DNA and cells by linking the DNA to a native functional group on the cell surface. The cells can be without cell walls or can have cell walls. The modified cells can be linked to a substrate surface and used in assay or bioreactors.
    Type: Application
    Filed: April 8, 2010
    Publication date: June 7, 2012
    Applicant: The Regents of the University of California
    Inventors: Shih-Chia Hsiao, Matthew B. Francis, Carolyn Bertozzi, Richard Mathies, Ravi Chandra, Erik Douglas, Amy Twite, Nicholas Toriello, Hiroaki Onoe