Patents by Inventor Shih-Chin Cheng

Shih-Chin Cheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and reagents for the analysis and purification of polysaccharides
    Patent number: 7998482
    Abstract: The disclosure provides fusion proteins comprising a carbohydrate recognition domain of an innate immunity receptor and a heterologous polypeptide. The fusion proteins of the disclosure may be used, for example, to fingerprint polysaccharide compositions and to purify polysaccharide compositions. Polysaccharide compositions include those isolated from Ganoderma lucidum (Reishi). The methods and reagents of the disclosure may also be used to identify innate immunity receptors and cell types that bind to polysaccharide compositions (including polysaccharide compositions associated with pathogens), whereupon modulators of the identified receptors can then be obtained. The fusion proteins also may be used to inhibit the interaction between a polysaccharide composition and an innate immunity receptor on a cell surface.
    Type: Grant
    Filed: July 31, 2009
    Date of Patent: August 16, 2011
    Assignee: Academia Sinica
    Inventors: Chi-Huey Wong, Shie-Liang Hsieh, Tsui-Ling Hsu, Shih-Chin Cheng, Szu-Ting Chen
  • METHODS AND REAGENTS FOR THE ANALYSIS AND PURIFICATION OF POLYSACCHARIDES
    Publication number: 20100055096
    Abstract: The disclosure provides fusion proteins comprising a carbohydrate recognition domain of an innate immunity receptor and a heterologous polypeptide. The fusion proteins of the disclosure may be used, for example, to fingerprint polysaccharide compositions and to purify polysaccharide compositions. Polysaccharide compositions include those isolated from Ganoderma lucidum (Reishi). The methods and reagents of the disclosure may also be used to identify innate immunity receptors and cell types that bind to polysaccharide compositions (including polysaccharide compositions associated with pathogens), whereupon modulators of the identified receptors can then be obtained. The fusion proteins also may be used to inhibit the interaction between a polysaccharide composition and an innate immunity receptor on a cell surface.
    Type: Application
    Filed: July 31, 2009
    Publication date: March 4, 2010
    Applicant: Academia Sinica
    Inventors: Chi-Huey Wong, Shie-Liang Hsieh, Tsui-Ling Hsu, Shih-Chin Cheng, Szu-Ting Chen
  • METHODS AND REAGENTS FOR THE ANALYSIS AND PURIFICATION OF POLYSACCHARIDES
    Publication number: 20070072247
    Abstract: The disclosure provides fusion proteins comprising a carbohydrate recognition domain of an innate immunity receptor and a heterologous polypeptide. The fusion proteins of the disclosure may be used, for example, to fingerprint polysaccharide compositions and to purify polysaccharide compositions. Polysaccharide compositions include those isolated from Ganoderma lucidum (Reishi). The methods and reagents of the disclosure may also be used to identify innate immunity receptors and cell types that bind to polysaccharide compositions (including polysaccharide compositions associated with pathogens), whereupon modulators of the identified receptors can then be obtained. The fusion proteins also may be used to inhibit the interaction between a polysaccharide composition and an innate immunity receptor on a cell surface.
    Type: Application
    Filed: August 31, 2006
    Publication date: March 29, 2007
    Applicant: Academia Sinica
    Inventors: Chie-Huey Wong, Shie-Liang Hsieh, Tsui-Ling Hsu, Shih-Chin Cheng, Szu-Ting Chen