Patents by Inventor SHIH-HSUN CHENG

SHIH-HSUN CHENG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Solid phase gold nanoparticle synthesis
    Patent number: 8734844
    Abstract: A method of synthesizing ligand-conjugated gold nanoparticles (AuNPs) is disclosed. The method comprises: a) providing an amine-modified silica particle; b) providing a solution comprising Au+3 ions; c) suspending the amine-modified silica particle in the solution comprising Au+3 ions; d) allowing the Au3+ ions to be adsorbed and/or immobilized onto the surface of the amine-modified silica particle; e) exposing the Au3+ ions immobilized onto the surface of the amine-modified silica particle to radiation to obtain bare gold nanoparticles (AuNPs) adsorbed and/or immobilized onto the surface of the amine-modified silica particle, wherein the bare AuNPs are without organic surface modifications; and f) reacting a ligand with the bare AuNPs adsorbed and/or immobilized onto the surface of the amine-modified SiNP and thereby obtain ligand-conjugated gold nanoparticles (AuNPs).
    Type: Grant
    Filed: May 17, 2011
    Date of Patent: May 27, 2014
    Assignee: National Health Research Institutes
    Inventors: Chia-Hung Lee, Wei-Neng Liao, Shih-Hsun Cheng, Jen-Kun Chen, Chung-Shi Yang, Leu-Wei Lo, Yeu-Kuang Hwu, Fong-Sian Lin
  • SOLID PHASE GOLD NANOPARTICLE SYNTHESIS
    Publication number: 20120130053
    Abstract: A method of synthesizing ligand-conjugated gold nanoparticles (AuNPs) is disclosed. The method comprises: a) providing an amine-modified silica particle; b) providing a solution comprising Au+3 ions; c) suspending the amine-modified silica particle in the solution comprising Au+3 ions; d) allowing the Au3+ ions to be adsorbed and/or immobilized onto the surface of the amine-modified silica particle; e) exposing the Au3+ ions immobilized onto the surface of the amine-modified silica particle to radiation to obtain bare gold nanoparticles (AuNPs) adsorbed and/or immobilized onto the surface of the amine-modified silica particle, wherein the bare AuNPs are without organic surface modifications; and f) reacting a ligand with the bare AuNPs adsorbed and/or immobilized onto the surface of the amine-modified SiNP and thereby obtain ligand-conjugated gold nanoparticles (AuNPs).
    Type: Application
    Filed: May 17, 2011
    Publication date: May 24, 2012
    Applicant: NATIONAL HEALTH RESEARCH INSTITUTES
    Inventors: CHIA-HUNG LEE, WEI-NENG LIAO, SHIH-HSUN CHENG, JEN-KUN CHEN, CHUNG-SHI YANG, LEU-WEI LO, YEU-KUANG HWU, FONG-SIAN LIN