Patents by Inventor Shih-Kang Fan

Shih-Kang Fan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200319135
    Abstract: A microfluidic chip suitable for detecting a microdroplet includes a first component, a second component, a channel layer, and a semiconductor chip. The first component includes a first substrate, a first electrode layer, and a first dielectric layer, wherein the first electrode layer is located between the first substrate and the first dielectric layer. The second component is disposed opposite to the first component and includes a second substrate, a second electrode layer, and a second dielectric layer. The channel layer is located between the first component and the second component. The semiconductor chip is disposed at one side of the first substrate and is exposed to the channel layer to assist in treating or detecting a sample or microdroplet. The microdroplet in the sample entering the channel layer is reacted with the semiconductor chip, and thus the sample is detected.
    Type: Application
    Filed: June 23, 2020
    Publication date: October 8, 2020
    Inventors: Shih-Kang Fan, CHEYANG CHEN
  • Patent number: 10724981
    Abstract: A microfluidic chip suitable for detecting a microdroplet includes a first component, a second component, a channel layer, and a semiconductor chip. The first component includes a first substrate, a first electrode layer, and a first dielectric layer, wherein the first electrode layer is located between the first substrate and the first dielectric layer. The second component is disposed opposite to the first component and includes a second substrate, a second electrode layer, and a second dielectric layer. The channel layer is located between the first component and the second component. The semiconductor chip is disposed at one side of the first substrate and is exposed to the channel layer to assist in treating or detecting a sample or microdroplet. The microdroplet in the sample entering the channel layer is reacted with the semiconductor chip, and thus the sample is detected.
    Type: Grant
    Filed: April 26, 2018
    Date of Patent: July 28, 2020
    Inventors: Shih-Kang Fan, Chih-Yuan Liang, Chia-Chann Shiue, Yuan-Sheng Lee, Yu-Kai Lai
  • Patent number: 10464062
    Abstract: A three-dimensional microfluidic platform including a substrate and a heterogeneous structure is provided. The heterogeneous structure located on the substrate includes prepolymer pattern, cured products, or a combination of at least one prepolymer patterns and at least one cured products, where the material characteristics of the cured products are different from each other, and the material characteristics of the prepolymer patterns are different from each other.
    Type: Grant
    Filed: October 26, 2017
    Date of Patent: November 5, 2019
    Assignee: National Taiwan University
    Inventors: Shih-Kang Fan, Min-Yu Chiang
  • Publication number: 20190113475
    Abstract: A microfluidic chip suitable for detecting a microdroplet includes a first component, a second component, a channel layer, and a semiconductor chip. The first component includes a first substrate, a first electrode layer, and a first dielectric layer, wherein the first electrode layer is located between the first substrate and the first dielectric layer. The second component is disposed opposite to the first component and includes a second substrate, a second electrode layer, and a second dielectric layer. The channel layer is located between the first component and the second component. The semiconductor chip is disposed at one side of the first substrate and is exposed to the channel layer to assist in treating or detecting a sample or microdroplet. The microdroplet in the sample entering the channel layer is reacted with the semiconductor chip, and thus the sample is detected.
    Type: Application
    Filed: April 26, 2018
    Publication date: April 18, 2019
    Applicant: National Taiwan University
    Inventors: Shih-Kang Fan, Chih-Yuan Liang, Chia-Chann Shiue, Yuan-Sheng Lee, Yu-Kai Lai
  • Publication number: 20180297027
    Abstract: A three-dimensional microfluidic platform including a substrate and a heterogeneous structure is provided. The heterogeneous structure located on the substrate includes prepolymer pattern, cured products, or a combination of at least one prepolymer patterns and at least one cured products, where the material characteristics of the cured products are different from each other, and the material characteristics of the prepolymer patterns are different from each other.
    Type: Application
    Filed: October 26, 2017
    Publication date: October 18, 2018
    Applicant: National Taiwan University
    Inventors: Shih-Kang Fan, Min-Yu Chiang
  • Publication number: 20180243081
    Abstract: The present invention provides a method of forming an intraocular lens. First, a chemical vapor deposition (CVD) process is performed to form a first poly-p-xylylene film, following by placing a solution drop on the first poly-p-xylylene film. A chemical vapor deposition encapsulation process is performed to form a second poly-p-xylylene film on the first poly-p-xylylene film and the solution drop.
    Type: Application
    Filed: April 25, 2018
    Publication date: August 30, 2018
    Inventors: Hsien-Yeh Chen, Shih-Kang Fan, Jyun-Ting Wu
  • Patent number: 9746465
    Abstract: A magnetic bead-based digital microfluidic immunoanalysis device and a method thereof are provided, which includes a lower plate, an upper plate disposed above the lower plate, a separating structure therebetween and a magnet disposed on the upper plate or the lower plate. The lower plate includes a first electrode layer including a plurality of channel electrodes with different sizes. A droplet containing few magnetic beads is adapted to be disposed on the lower plate and corresponding to the channel electrodes. The magnet attracts the magnetic beads to approach to the smaller one of the channel electrodes though a magnetic force, and when a voltage is applied to the first electrode layer, the droplet is divided to a detection portion with the magnetic beads and a waste-liquid portion without the magnetic beads respectively corresponding to the smaller one and the larger one of the channel electrodes through a dual-direction electrowetting-on-dielectric force.
    Type: Grant
    Filed: June 15, 2015
    Date of Patent: August 29, 2017
    Assignee: National Chiao Tung University
    Inventors: Wensyang Hsu, Cheng-Yeh Huang, Po-Yen Tsai, Po-Huai Shih, Shih-Kang Fan, Da-Jeng Yao, Cheng-Hsien Liu, Hong-Yuan Huang
  • Publication number: 20170172728
    Abstract: The present invention provides an intraocular lens, including a first poly-p-xylylene film, a second poly-p-xylylene film and a liquid drop. The liquid drop is disposed between the first poly-p-xylylene film and the second poly-p-xylylene. The present invention further provides a method of forming the same.
    Type: Application
    Filed: January 18, 2016
    Publication date: June 22, 2017
    Inventors: Hsien-Yeh Chen, Shih-Kang Fan, Jyun-Ting Wu
  • Patent number: 9663751
    Abstract: The present disclosure illustrates a platform system for in vitro cell co-cultivation with automatic trapping function. The platform system aims to develop a bio-chip applied in cell culture systems, and has several features. The first feature is that this co-cultivation platform can construct a micro environment suitable for culture of various cells. The second feature is dynamic perfusion. The microfluidic system is used to dynamically replace the culture medium, in order to maintain an appropriate environment for the growth of cells. The third feature is the automatic trapping. The cells to be cultured can be trapped in a suitable location according to the flow resistance, so that the damaged on the cell caused by manual operation can be minimized.
    Type: Grant
    Filed: January 2, 2015
    Date of Patent: May 30, 2017
    Assignee: NATIONAL TSING HUA UNIVERSITY
    Inventors: Ting-Ju Yueh, Chi-Fan Chen, Kuo-Wei Chang, Pei-Yu Chang, Cheng-Hsien Liu, Hong-Yuan Huang, Chin-Jung Li, Chang-Hung Tien, Da-Jeng Yao, Shih-Kang Fan, Wen-Syang Hsu
  • Publication number: 20160274098
    Abstract: A magnetic bead-based digital microfluidic immunoanalysis device and a method thereof are provided, which includes a lower plate, an upper plate disposed above the lower plate, a separating structure therebetween and a magnet disposed on the upper plate or the lower plate. The lower plate includes a first electrode layer including a plurality of channel electrodes with different sizes. A droplet containing few magnetic beads is adapted to be disposed on the lower plate and corresponding to the channel electrodes. The magnet attracts the magnetic beads to approach to the smaller one of the channel electrodes though a magnetic force, and when a voltage is applied to the first electrode layer, the droplet is divided to a detection portion with the magnetic beads and a waste-liquid portion without the magnetic beads respectively corresponding to the smaller one and the larger one of the channel electrodes through a dual-direction electrowetting-on-dielectric force.
    Type: Application
    Filed: June 15, 2015
    Publication date: September 22, 2016
    Inventors: Wensyang Hsu, Cheng-Yeh Huang, Po-Yen Tsai, Po-Huai Shih, Shih-Kang Fan, Da-Jeng Yao, Cheng-Hsien Liu, Hong-Yuan Huang
  • Publication number: 20150291926
    Abstract: The present disclosure illustrates a platform system for in vitro cell co-cultivation with automatic trapping function. The platform system aims to develop a bio-chip applied in cell culture systems, and has several features. The first feature is that this co-cultivation platform can construct a micro environment suitable for culture of various cells. The second feature is dynamic perfusion. The microfluidic system is used to dynamically replace the culture medium, in order to maintain an appropriate environment for the growth of cells. The third feature is the automatic trapping. The cells to be cultured can be trapped in a suitable location according to the flow resistance, so that the damaged on the cell caused by manual operation can be minimized.
    Type: Application
    Filed: January 2, 2015
    Publication date: October 15, 2015
    Inventors: Ting-Ju YUEH, Chi-Fan CHEN, Kuo-Wei CHANG, Pei-Yu CHANG, Cheng-Hsien LIU, Hong-Yuan HUANG, Chin-Jung LI, Chang-Hung TIEN, Da-Jeng YAO, Shih-Kang FAN, Wen-Syang HSU
  • Patent number: 8771493
    Abstract: A liquid dielectrophoretic device comprises: a first container unit defining a first micro containing space including an electrode pair for generating a dielectrophoretic force; a second container unit defining a second micro containing space and including an electrode pair for generating a dielectrophoretic force; and a fluid channel unit defining a micro-channel between the first and second micro containing spaces and including an electrode pair having a middle region layer that has first and second enlarged sections and a middle section disposed between the first and second enlarged sections. The first and second enlarged sections are enlarged gradually from the middle section to the first and second micro containing spaces. A method for controllably transporting a liquid using the liquid dielectrophoretic device is also disclosed.
    Type: Grant
    Filed: July 8, 2011
    Date of Patent: July 8, 2014
    Assignee: National Chiao Tung University
    Inventors: Shih-Kang Fan, I-Pei Lu
  • Patent number: 8451301
    Abstract: A color display device includes a plurality of pixel display elements and a driving circuit. Each of the pixel display elements includes a plurality of sub-pixel display elements. Each of the sub-pixel display elements includes first and second supports, first and second electrodes attached to inner faces of the first and second supports, respectively, a solution disposed between the first and second electrodes, and particles dispersed in the solution. The particles of the sub-pixel display elements of a same one of the pixel display elements are electrically polarizable by voltage signals supplied by the driving circuit, the voltage signals having the same predetermined driving frequency.
    Type: Grant
    Filed: August 31, 2010
    Date of Patent: May 28, 2013
    Assignee: National Chiao Tung University
    Inventors: Shih-Kang Fan, Cheng-Pu Chiu, Shih-Chiang Chen
  • Patent number: 8428416
    Abstract: A device for transmitting light signals includes two electrode plates, a spacing structure, a cladding fluid, and a core fluid. The spacing structure, the cladding and core fluids are disposed between the electrode plates. The refractive index of the core fluid is higher than that of the cladding fluid. The core fluid is located on an electrode of one of the electrode plates, and its shape corresponds to the shape of that electrode. The shape and position is changeable and programmable by the electrodes of one of the electrode plates. The core fluid is further surrounded by the cladding fluid, forming an optical waveguide. Via these arrangements, the interface between the core and cladding fluids is much smoother than that between a fluid and a solid, so that the light signals are less likely to scatter while transmitted, in the core fluid. Therefore, the attenuation and reduction of the intensity of the light signals can be decreased. A method for transmitting light signals is also provided.
    Type: Grant
    Filed: June 18, 2010
    Date of Patent: April 23, 2013
    Assignee: National Chiao Tung University
    Inventors: Shih-Kang Fan, Chia-Chi Chien, Yi-Wen Lu
  • Patent number: 8400593
    Abstract: An electro-optical device includes a body of fluid, a lower conductor layer disposed below the body of fluid, and a dielectric layer disposed between the body of fluid and the lower conductor layer, connected to the lower conductor layer and supporting the body of fluid. The dielectric layer includes a matrix and a liquid crystal material disposed in the matrix and including liquid crystal molecules. The dielectric layer has a segment disposed adjacent to the fluid. When the segment of the dielectric layer is exposed to an electric field, the body of fluid undergoes electrowetting or dielectrophoresis mechanism, and the orientation of the liquid crystal molecules that are disposed in the segment of the dielectric layer is changed.
    Type: Grant
    Filed: April 22, 2010
    Date of Patent: March 19, 2013
    Assignee: National Chiao Tung University
    Inventors: Shih-Kang Fan, Cheng-Pu Chiu
  • Patent number: 8390564
    Abstract: A display including a first substrate, a first electrode, a second substrate, a second electrode, and a mixed solution is provided. The first electrode is disposed on the first substrate, and the second electrode is disposed on the second substrate. In addition, the mixed solution is disposed between the first electrode and the second electrode. Moreover, the mixed solution includes a solution and a plurality of first neutral micro-particles disposed in the solution.
    Type: Grant
    Filed: March 31, 2008
    Date of Patent: March 5, 2013
    Assignees: Chunghwa Picture Tubes, Ltd., National Chiao Tung University
    Inventors: Shih-Kang Fan, Cheng-Pu Chiu, Chi-Neng Mo, Mei-Tsao Chiang
  • Publication number: 20120301564
    Abstract: A microfluidic system for creating encapsulated droplets whose shells can be further removed comprises: two electrode plates and a spacing structure disposed between the two electrode plates. One of the electrode plates has three reservoir electrodes and a plurality of channel electrodes. The three electrodes are respectively used for accommodating a shell liquid, a core liquid, and a removing liquid which is able to remove the shell liquid. The channel electrodes are used for communicating droplets among the three reservoir electrodes. Via these arrangements, the microfluidic system can create a quantitative shell droplet and a quantitative core droplet, and then merge the shell and core droplets to form an encapsulated droplet. Moreover, the shell of the encapsulated droplet can be removed by mixing it with the removing liquid. This invention is further provided with a method for creating an encapsulated droplet with a removable shell.
    Type: Application
    Filed: August 6, 2012
    Publication date: November 29, 2012
    Applicant: NATIONAL CHIAO TUNG UNIVERSITY
    Inventors: SHIH-KANG FAN, YAO-WEN HSU, CHIUN-HSUN CHEN
  • Patent number: 8287708
    Abstract: A microfluidic system for creating encapsulated droplets whose shells can be further removed comprises: two electrode plates and a spacing structure disposed between the two electrode plates. One of the electrode plates has three reservoir electrodes and a plurality of channel electrodes. The three electrodes are respectively used for accommodating a shell liquid, a core liquid, and a removing liquid which is able to remove the shell liquid. The channel electrodes are used for communicating droplets among the three reservoir electrodes. Via these arrangements, the microfluidic system can create a quantitative shell droplet and a quantitative core droplet, and then merge the shell and core droplets to form an encapsulated droplet. Moreover, the shell of the encapsulated droplet can be removed by mixing it with the removing liquid. This invention is further provided with a method for creating an encapsulated droplet with a removable shell.
    Type: Grant
    Filed: June 15, 2010
    Date of Patent: October 16, 2012
    Assignee: National Chiao Tung University
    Inventors: Shih-Kang Fan, Yao-Wen Hsu, Chiun-Hsun Chen
  • Patent number: 8232961
    Abstract: A pixel driving structure of a particle display displaying three colors and a method for displaying colors thereof are provided. The pixel driving structure includes a first substrate; a first electrode layer disposed on a surface of the first substrate; a second substrate disposed opposite to the first substrate; a second electrode layer on the second substrate; a particle solution disposed between the first electrode layer and the second electrode layer and having a first color solution, a plurality of second color positive particles, and a plurality of third color negative particles; and an alternating/direct power supply connecting with the first and second electrode layers. A method for displaying color includes steps of applying an alternating voltage to display a first color; applying a first direct voltage to display a third color; and applying a second direct voltage to display a second color.
    Type: Grant
    Filed: August 17, 2009
    Date of Patent: July 31, 2012
    Assignees: Chunghwa Picture Tubes, Ltd., National Chiao Tung University
    Inventors: Shih-Kang Fan, Cheng-Pu Chiu, Ching-Hsiang Hsu, Chi-Neng Mo, Mei-Tsao Chiang
  • Publication number: 20120160680
    Abstract: A microfluidic system includes a first electrode plate having a first substrate and a first electrode layer, wherein the first electrode layer has a plurality of continuously-arranged driving electrodes; a second electrode plate having a second substrate and a second electrode layer, wherein the second electrode layer corresponds to the first electrode layer; a spacing structure disposed between the first electrode plate and the second electrode plate so as to define a fluidic space therebetween; at least one fluid manipulatably received in the fluidic space, wherein the fluid has at least one gas bubble having a reaction gas thereinside, and the gas bubble is an enclosure structure. An electric potential is applied for driving the fluid and then controlling the position of the gas bubble. A gas breakdown voltage is applied to electrically discharge the gas in the gas bubble.
    Type: Application
    Filed: June 14, 2011
    Publication date: June 28, 2012
    Applicant: NATIONAL CHIAO TUNG UNIVERSITY
    Inventors: SHIH-KANG FAN, LING-PIN TSAI