Abstract: A method for treating sleeping or movement disorder is provided. The method includes the operations as follows. A brainwave of a patient with sleeping or movement disorder is recorded. An onset of a STW oscillation episode from the brainwave is identified, wherein the STW oscillation episode is a STW signal having an oscillation frequency in a range of from about 2 Hz to about 4 Hz. a first stimulation is delivered to the patient when the onset of the STW oscillation episode is identified from the brainwave. The first stimulation is adapted according to a measurable feature of the STW oscillation episode. A system for treating sleeping or movement disorder is also provided.

Abstract: A method for treating movement disorders is provided. The method includes the following operations. A central nervous signal of a patient with movement disorders is recorded. A first stimulation is delivered from a stimulator to the patient when an oscillation episode in a range of from about 3 Hz to about 20 Hz is observed in the central nervous signal. The first stimulation is adapted according to a measurable feature of the oscillation episode. The system for treating movement disorders is also provided.

Abstract: A method for treating neural disorders is provided. The method includes the following operation. A stimulation is delivered to a layer of a cortex of a patient with a neural disorder, wherein the stimulation is delivered to less than all layers of the cortex of the patient. In another method for treating neural disorders, a stimulation is delivered to a cortex of a patient with a neural disorder, wherein the stimulation delivered to one of a plurality of layers of the cortex is stronger than to other layers of the cortex. The system for treating neural disorder is also provided. The system includes a stimulation signal generator and a layer-specific stimulation means. The layer-specific stimulation means is coupled to the stimulation signal generator, configured to deliver a stimulation to a specific layer of a cortex of a patient with a neural disorder.

Abstract: A method for treating neural disorders is provided, The method includes the following operation. A stimulation is delivered to a layer of a cortex of a patient with a neural disorder, wherein the stimulation is delivered to less than all layers of the cortex of the patient. In another method for treating neural disorders, a stimulation is delivered to a cortex of a patient with a neural disorder, wherein the stimulation delivered to one of a plurality of layers of the cortex is stronger than to other layers of the cortex. The system for treating neural disorder is also provided. The system includes a stimulation signal generator and a layer-specific stimulation means. The layer-specific stimulation means is coupled to the stimulation signal generator, configured to deliver a stimulation to a specific layer of a cortex of a patient with a neural disorder.

Abstract: A method for treating movement disorders is provided. The method includes the following operations. A central nervous signal of a patient with movement disorders is recorded. A first stimulation is delivered from a stimulator to the patient when an oscillation episode in a range of from about 3 Hz to about 20 Hz is observed in the central nervous signal. The first stimulation is adapted according to a measurable feature of the oscillation episode. The system for treating movement disorders is also provided.

Abstract: The present invention discloses a method for modifying a carbon nanotube electrode interface, which modifies carbon nanotubes used as a neuron-electrode interface by performing three stages of modifications and comprises the steps of: carboxylating carbon nanotubes to provide carboxyl functional groups and improve the hydrophilicity of the carbon nanotubes; acyl-chlorinating the carboxylated carbon nanotubes to replace the hydroxyl functional groups of the carboxyl functional groups with chlorine atoms; and aminating the acyl-chlorinated carbon nanotubes to replace the chlorine atoms with a derivative having amine functional groups at the terminal thereof. The modified carbon nanotubes used as the neuron-electrode interface has lower impedance and higher adherence to nerve cells. Thus is improved the quality of neural signal measurement.

Abstract: The present invention discloses a method for modifying a carbon nanotube electrode interface, which modifies carbon nanotubes used as a neuron-electrode interface by performing three stages of modifications and comprises the steps of: carboxylating carbon nanotubes to provide carboxyl functional groups and improve the hydrophilicity of the carbon nanotubes; acyl-chlorinating the carboxylated carbon nanotubes to replace the hydroxyl functional groups of the carboxyl functional groups with chlorine atoms; and aminating the acyl-chlorinated carbon nanotubes to replace the chlorine atoms with a derivative having amine functional groups at the terminal thereof. The modified carbon nanotubes used as the neuron-electrode interface has lower impedance and higher adherence to nerve cells. Thus is improved the quality of neural signal measurement.

Abstract: A novel multifunctional nano-probe interface is proposed for applications in neural stimulation and detecting. The nano-probe interface structure consists of a carbon nanotube coated with a thin isolation layer, a micro-electrode substrate array, and a controller IC for neural cell recording and stimulation. The micro-electrode substrate array contains wires connecting the carbon nanotube with the controller IC, as well as microfluidic channels for supplying neural tissues with essential nutrition and medicine. The carbon nanotube is disposed on the micro-electrode substrate array made by silicon, coated with a thin isolation layer around thereof, and employed as a nano-probe for neural recording and stimulation.