Patents by Inventor Shihai Huang

Shihai Huang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EGFR ASSAY
    Publication number: 20200172983
    Abstract: Provided herein is technology relating to detecting molecular markers relevant to cancer and particularly, but not exclusively, to methods and compositions for quantifying and/or detecting EGFR mRNA and/or EGFRvIII mRNA in biological samples.
    Type: Application
    Filed: January 2, 2020
    Publication date: June 4, 2020
    Inventors: Jeffrey D. Wuitschick, Kevin S. Nelson, Shihai Huang, Rupinder Kular, Carolyn Mullen, James Rhoads
  • EGFR assay
    Patent number: 10538815
    Abstract: Provided herein is technology relating to detecting molecular markers relevant to cancer and particularly, but not exclusively, to methods and compositions for quantifying and/or detecting EGFR mRNA and/or EGFRvIII mRNA in biological samples.
    Type: Grant
    Filed: June 23, 2016
    Date of Patent: January 21, 2020
    Assignee: ABBOTT MOLECULAR INC.
    Inventors: Jeffrey D. Wuitschick, Kevin S. Nelson, Shihai Huang, Rupinder Kular, Carolyn Mullen, James Rhoads
  • ASSAY FOR DETECTING HEPATITIS C VIRUS (HCV)
    Publication number: 20190100813
    Abstract: The disclosure is directed to methods, kits, and compositions, for amplifying and detecting a human hepatitis C virus (HCV) in a sample, which comprises a variety of combinations of forward oligonucleotide primers, reverse oligonucleotide primers, and oligonucleotide probes.
    Type: Application
    Filed: October 3, 2018
    Publication date: April 4, 2019
    Inventors: Dan Toolsie, Shihai Huang, Hong Su, Darren Drapp, William Caminiti, Kara Nordin, Sevim Arslan, Sara Jones
  • ASSAY FOR DETECTING HUMAN IMMUNODEFICIENCY VIRUS (HIV)
    Publication number: 20190100812
    Abstract: The disclosure is directed to methods, kits, and compositions for amplifying and detecting a human immunodeficiency virus-1 (HIV-1) in a sample, which comprises a variety of combinations of forward oligonucleotide primers, reverse oligonucleotide primers, and oligonucleotide probes.
    Type: Application
    Filed: October 2, 2018
    Publication date: April 4, 2019
    Inventors: Jeffrey Wuitschick, Shihai Huang, Tomasz Krupinski, John Karavitis, John Salituro, Anna Sobol
  • MAXIMIZING DNA YIELD OF BLOOD SPECIMENS COLLECTED IN RAPID CLOT TUBES
    Publication number: 20180087049
    Abstract: The invention provides methods for isolating DNA from a blood sample collected into tubes containing a rapid clot activator, which involves the use of a lysis buffer comprising an alcohol.
    Type: Application
    Filed: September 7, 2017
    Publication date: March 29, 2018
    Inventors: Wai-Bing Mak, Dominik Duelli, Shihai Huang
  • TARGET SEQUENCE ENRICHMENT
    Publication number: 20170321253
    Abstract: The present invention provides methods, systems, kits, and compositions for magnetically purifying target nucleic acid sequences from a sample using bait molecules configured to bind both target nucleic acid sequences and magnetic binding particles. In certain embodiments, the bait molecules comprise a short target capture sequence (e.g., 18 to 48 bases), and the methods employ a short hybridization time (e.g., 1-4 hours) and a low hybridization temperature (e.g., about room temperature).
    Type: Application
    Filed: June 19, 2017
    Publication date: November 9, 2017
    Inventors: Hong Su, Shihai Huang
  • EGFR ASSAY
    Publication number: 20160376665
    Abstract: Provided herein is technology relating to detecting molecular markers relevant to cancer and particularly, but not exclusively, to methods and compositions for quantifying and/or detecting EGFR mRNA and/or EGFRvIII mRNA in biological samples.
    Type: Application
    Filed: June 23, 2016
    Publication date: December 29, 2016
    Inventors: Jeffrey D. Wuitschick, Kevin S. Nelson, Shihai Huang, Rupinder Kular, Carolyn Mullen, James Rhoads
  • TARGET SEQUENCE ENRICHMENT
    Publication number: 20140287408
    Abstract: The present invention provides methods, systems, kits, and compositions for magnetically purifying target nucleic acid sequences from a sample using bait molecules configured to bind both target nucleic acid sequences and magnetic binding particles. In certain embodiments, the bait molecules comprise a short target capture sequence (e.g., 18 to 48 bases), and the methods employ a short hybridization time (e.g., 1-4 hours) and a low hybridization temperature (e.g., about room temperature).
    Type: Application
    Filed: March 13, 2014
    Publication date: September 25, 2014
    Applicant: Abbott Molecular Inc.
    Inventors: Hong Su, Shihai Huang
  • MULTIPLEX ALLELE DETECTION
    Publication number: 20140274779
    Abstract: Provided herein is technology relating to nucleic acid detection and particularly, but not exclusively, to methods and compositions for the simultaneous detection of multiple nucleic acids.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Applicant: Abbott Molecular Inc.
    Inventors: Shihai Huang, Hong Su
  • PRAME DETECTION ASSAYS
    Publication number: 20140072971
    Abstract: Provided herein are molecular assays, including oligonucleotides and other reagents, for the detection and analysis of PRAME (Preferentially Expressed Antigen in Melanoma). The assays find use, for example, as diagnostic and prognostic applications, including use in assessing therapeutic courses of action.
    Type: Application
    Filed: August 30, 2013
    Publication date: March 13, 2014
    Applicant: ABBOTT LABORATORIES
    Inventors: Jeffrey D. Wuitschick, Shihai Huang
  • Image based correction for unwanted light signals in a specific region of interest
    Patent number: 8249381
    Abstract: A method for correcting the signal in an image having a plurality of regions of interest, the method comprising the steps of: (a) providing an image having a plurality of regions of interest, these regions of interest having areas between them; (b) determining a region of correction between at least two regions of interest; (c) calculating a correction signal from the region of correction; and (d) using the correction signal to correct a measured signal from one or more regions of interest.
    Type: Grant
    Filed: February 17, 2010
    Date of Patent: August 21, 2012
    Assignee: Abbott Laboratories
    Inventors: James C. Kolterman, Eric B. Shain, Robert C. Gray, Shihai Huang, Gavin Cloherty
  • Image Based Correction For Unwanted Light Signals In A Specific Region Of Interest
    Publication number: 20100142848
    Abstract: A method for correcting the signal in an image having a plurality of regions of interest, the method comprising the steps of: (a) providing an image having a plurality of regions of interest, these regions of interest having areas between them; (b) determining a region of correction between at least two regions of interest; (c) calculating a correction signal from the region of correction; and (d) using the correction signal to correct a measured signal from one or more regions of interest.
    Type: Application
    Filed: February 17, 2010
    Publication date: June 10, 2010
    Applicant: Abbott Laboratories
    Inventors: James C. Kolterman, Eric B. Shain, Robert C. Gray, Shihai Huang, Gavin A. Cloherty
  • Image based correction for unwanted light signals in a specific region of interest
    Publication number: 20070116376
    Abstract: A method for correcting the signal in an image having a plurality of regions of interest, the method comprising the steps of: (a) providing an image having a plurality of regions of interest, these regions of interest having areas between them; (b) determining a region of correction between at least two regions of interest; (c) calculating a correction signal from the region of correction; and (d) using the correction signal to correct a measured signal from one or more regions of interest.
    Type: Application
    Filed: November 18, 2005
    Publication date: May 24, 2007
    Inventors: James Kolterman, Eric Shain, Robert Gray, Shihai Huang, Gavin Cloherty
  • Double stranded linear nucleic acid probe and uses thereof
    Publication number: 20050227257
    Abstract: A double-stranded nucleic acid hybridization probe and methods of using the same are described. The probe described is particularly suited for real-time RT-PCR reactions and has high tolerance to mismatches.
    Type: Application
    Filed: November 30, 2004
    Publication date: October 13, 2005
    Inventors: Klara Abravaya, John Hackett, Shihai Huang, Ka-Cheung Luk, John Salituro, Larry Morrison