Patents by Inventor Shihe HU

Shihe HU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quinoline compound and use thereof
    Publication number: 20230014962
    Abstract: Disclosed are a class of quinoline compounds and use thereof. This class of compounds has good inhibitory activity to a fibroblast growth factor receptor 4 (FGFR4), may be used as a receptor tyrosine kinase inhibitor, in particular as an FGFR4 kinase irreversible inhibitor, and is used for preparing drugs for preventing and/or treating FGFR4 overexpression-mediated diseases in organisms and diseases associated with angiogenesis or cancer metastasis.
    Type: Application
    Filed: December 22, 2020
    Publication date: January 19, 2023
    Inventors: Libo YAN, Shihe HU, Ya WANG, Yu LIU
  • Deuterated 3-(4,5-substituted aminopyrimidine)phenyl derivatives and use thereof
    Patent number: 10654851
    Abstract: A type of deuterated 3-(4,5-substituted aminopyrimidine)phenyl derivatives and use thereof. The derivatives are compounds of Formula (I) or pharmaceutically acceptable salts thereof. These compounds or salts thereof can be used for treatment or prevention of diseases or illnesses through certain mutant forms of epidermal growth factor receptors, inhibit the growth of various tumor cells effectively, and inhibit other proteases of EGFR and Her families, they can be used for preparing anti-tumor drugs.
    Type: Grant
    Filed: September 18, 2017
    Date of Patent: May 19, 2020
    Assignee: NANJING CHUANGTE PHARMACEUTICAL TECHNOLOGY CO., LTD.
    Inventors: Yongqiang Zhu, Zhaogang Liu, Chao Feng, Shihe Hu, Hao Chen, Enhe Bai, Jie Wang, Jingmiao Shi
  • DEUTERATED 3-(4,5-SUBSTITUTED AMINOPYRIMIDINE)PHENYL DERIVATIVES AND USE THEREOF
    Publication number: 20190225610
    Abstract: A type of deuterated 3-(4,5-substituted aminopyrimidine)phenyl derivatives and use thereof. The derivatives are compounds of Formula (I) or pharmaceutically acceptable salts thereof. These compounds or salts thereof can be used for treatment or prevention of diseases or illnesses through certain mutant forms of epidermal growth factor receptors, inhibit the growth of various tumor cells effectively, and inhibit other proteases of EGFR and Her families, they can be used for preparing anti-tumor drugs.
    Type: Application
    Filed: September 18, 2017
    Publication date: July 25, 2019
    Inventors: Yongqiang ZHU, Zhaogang LIU, Chao FENG, Shihe HU, Hao CHEN, Enhe BAI, Jie WANG, Jingmiao SHI