Patents by Inventor Shiho Tokonami
Shiho Tokonami has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11719603Abstract: A collecting apparatus for bacteria includes: a laser beam source configured to emit a laser beam; and a container configured to hold a dispersion liquid in which a plurality of bacteria are dispersed. The container has a bottom surface and an inner side surface. A thin film for converting the laser beam from the laser beam source into heat is formed on the bottom surface. At the inner side surface, immersion wetting occurs by the dispersion liquid when the inner side surface comes into contact with the dispersion liquid. The thin film is configured to produce a thermal convection in the dispersion liquid by heating the dispersion liquid. The inner side surface is configured to produce a Marangoni convection at a gas-liquid interface as an interface between the dispersion liquid and gas around the dispersion liquid.Type: GrantFiled: February 28, 2018Date of Patent: August 8, 2023Assignee: University Public Corporation OsakaInventors: Takuya Iida, Shiho Tokonami, Yasuyuki Yamamoto
-
Publication number: 20230197995Abstract: The present invention provides an electrochemical device utilizing microorganisms and capable of outputting sufficient power in a short time after boot-up, by means of an electrochemical device comprising a first electrode comprising a surface layer portion having at least one pore with an opening, wherein the pore has a conductive section at least on an inner face thereof, the first electrode has a conduction path that electrically connects the conductive sections of the pores to each other, and each pore carries electron-donating microorganisms of different classifications or different electron-donating microorganisms of the same classification, or electron-donating microorganisms with average particle sizes significantly different from each other; and a method of producing the same.Type: ApplicationFiled: May 14, 2021Publication date: June 22, 2023Applicant: UNIVERSITY PUBLIC CORPORATION OSAKAInventors: Shiho TOKONAMI, Takuya IIDA
-
Publication number: 20230194413Abstract: A microscopic object detection system includes a collecting kit and a detection device. The collecting kit has a thin film for converting light into heat and is configured to be capable of holding a sample on the thin film. The detection device detects a plurality of microscopic objects in the sample by collecting the plurality of microscopic objects dispersed in the sample with the collecting kit. The detection device includes a laser module, an optical receiver, and a controller. The laser module emits a laser beam with which the collecting kit is irradiated. The optical receiver detects the laser beam from the sample held by the collecting kit and outputs a detection signal thereof. The controller calculates an amount of the plurality of microscopic objects collected in the sample based on a change of the detection signal over time.Type: ApplicationFiled: May 7, 2021Publication date: June 22, 2023Inventors: Takuya IIDA, Shiho TOKONAMI, Hiroki ISHIKAWA, Tsutomu YAMASAKI, Hirohito WASHIDA
-
Patent number: 11561160Abstract: The purpose of the present invention is to collect a plurality of microscopic objects dispersed in a liquid by light irradiation, and also trap them. A collecting device for bacteria collects a plurality of bacteria dispersed in a sample liquid. The collecting device is provided with a laser beam source that emits laser beam and a honeycomb polymer film constituted so as to be able to hold the liquid. Walls prescribing pores for trapping the plurality of bacteria dispersed in the liquid are formed on the honeycomb polymer film, and also a thin film that includes a material for converting light from the laser beam source to heat is formed on the honeycomb polymer film. The thin film heats the liquid of the sample through the conversion of the laser beam from the laser beam source to heat, thereby causing a convection in the liquid.Type: GrantFiled: May 11, 2017Date of Patent: January 24, 2023Assignee: University Public Corporation OsakaInventors: Shiho Tokonami, Takuya Iida, Kazushi Fujioka
-
Publication number: 20220324700Abstract: A method of manufacturing a photothermal conversion element includes preparing a solid material and forming a processed region processed by irradiation of the solid material with a laser beam. The forming includes grain refining the solid material to blacken the processed region.Type: ApplicationFiled: August 28, 2020Publication date: October 13, 2022Inventors: Takuya Iida, Atsuko Kosuga, Shiho Tokonami
-
Publication number: 20220326249Abstract: A method for detecting an analyte includes first to third steps. The first step is distributing a sample containing a bead modified with a host molecule that is specifically bound to the analyte in a microchannel using a syringe pump. The second step is irradiating the sample with non-resonant light that is light outside a wavelength range of electronic resonance of the bead. The third step is detecting the analyte based on a signal from a camera that receives the light from the sample.Type: ApplicationFiled: August 28, 2020Publication date: October 13, 2022Inventors: Takuya Iida, Shiho Tokonami, Ikuhiko Nakase
-
Publication number: 20220226814Abstract: A method of collecting resin beads includes first to fourth steps. The first step is a step of preparing a sample on a thin film provided on an upper surface of a substrate. The second step is a step of irradiating the thin film with a laser beam and a laser beam with the laser beam and the laser beam being distant from each other. The third step is a step of producing a microbubble at a position irradiated with the laser beam and producing a microbubble at a position irradiated with the laser beam, by heating the sample by irradiation with the laser beams. The fourth step is a step of collecting a plurality of resin beads in a region between the microbubble and the microbubble by producing convection of the sample in a direction perpendicular to a direction of alignment of the microbubble and the microbubble.Type: ApplicationFiled: April 22, 2020Publication date: July 21, 2022Inventors: Takuya IIDA, Shiho TOKONAMI, Hiroki ISHIKAWA, Tsutomu YAMASAKI
-
Publication number: 20220178798Abstract: A laser module includes a plurality of light emission regions and the plurality of light emission regions emit a plurality of laser beams. An optical waveguide and a lens condense the plurality of laser beams to an identical focal point. An adjustment mechanism is configured to adjust relative positional relation between the sample stage and a condenser lens (the optical waveguide and the lens). A controller is configured to switch between a single-point irradiation mode and a multi-point irradiation mode. The single-point irradiation mode refers to a mode in which the adjustment mechanism is controlled such that the focal point of the plurality of laser beams falls on the thin film. The multi-point irradiation mode refers to a mode in which the adjustment mechanism is controlled such that the focal point does not fall on the thin film.Type: ApplicationFiled: April 22, 2020Publication date: June 9, 2022Inventors: Takuya IIDA, Shiho TOKONAMI, Hiroki ISHIKAWA, Tsutomu YAMASAKI
-
Publication number: 20200182770Abstract: The purpose of the present invention is to collect a plurality of microscopic objects dispersed in a liquid by light irradiation, and also trap them. A collecting device for bacteria collects a plurality of bacteria dispersed in a sample liquid. The collecting device is provided with a laser beam source that emits laser beam and a honeycomb polymer film constituted so as to be able to hold the liquid. Walls prescribing pores for trapping the plurality of bacteria dispersed in the liquid are formed on the honeycomb polymer film, and also a thin film that includes a material for converting light from the laser beam source to heat is formed on the honeycomb polymer film. The thin film heats the liquid of the sample through the conversion of the laser beam from the laser beam source to heat, thereby causing a convection in the liquid.Type: ApplicationFiled: May 11, 2017Publication date: June 11, 2020Applicant: Osaka Prefecture University Public CorporationInventors: Shiho TOKONAMI, Takuya IIDA, Kazushi FUJIOKA
-
Publication number: 20190383708Abstract: A collecting apparatus for bacteria includes: a laser beam source configured to emit a laser beam; and a container configured to hold a dispersion liquid in which a plurality of bacteria are dispersed. The container has a bottom surface and an inner side surface. A thin film for converting the laser beam from the laser beam source into heat is formed on the bottom surface. At the inner side surface, immersion wetting occurs by the dispersion liquid when the inner side surface comes into contact with the dispersion liquid. The thin film is configured to produce a thermal convection in the dispersion liquid by heating the dispersion liquid. The inner side surface is configured to produce a Marangoni convection at a gas-liquid interface as an interface between the dispersion liquid and gas around the dispersion liquid.Type: ApplicationFiled: February 28, 2018Publication date: December 19, 2019Inventors: Takuya Iida, Shiho Tokonami, Yasuyuki Yamamoto
-
Patent number: 9903861Abstract: A detection device detects an analyte that may be contained in a specimen. The detection device includes a plurality of gold nanoparticles, an optical trapping light source, an illumination light source, an objective lens, an image pick-up device, and a computation unit. The plurality of gold nanoparticles are each modified with a probe DNA allowing the analyte to specifically adhere thereto. The optical trapping light source emits polarized light for assembling the plurality of gold nanoparticles together. The objective lens focuses and introduces the polarized light into a liquid containing a specimen and the plurality of gold nanoparticles. The image pick-up device receives light from the liquid. The computation unit detects an analyte based on a signal received from the image pick-up device.Type: GrantFiled: May 30, 2014Date of Patent: February 27, 2018Assignee: Osaka Prefecture University Public CorporationInventors: Takuya Iida, Shiho Tokonami
-
Patent number: 9797842Abstract: Disclosed is a device and method allowing a trace amount of a target substance to be detected. A metallic nanoparticle assembly structure is formed of metallic nanoparticles assembled together and modified with a host molecule allowing the target substance to specifically adhere thereto. A metallic nanorod is modified with a host molecule allowing the target substance to specifically adhere thereto. The metallic nanorod is conjugated to the metallic nanoparticle assembly structure by the target substance. An extinction spectrum of localized surface plasmon resonance or a surface enhanced Raman scattering (SERS) spectrum induced in the metallic nanoparticle assembly structure and the metallic nanostructure is measured with a spectroscope. The target substance is detected based on that spectrum.Type: GrantFiled: December 8, 2011Date of Patent: October 24, 2017Assignee: OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATIONInventors: Shiho Tokonami, Takuya Iida, Yojiro Yamamoto, Hiroshi Shiigi, Tsutomu Nagaoka
-
Publication number: 20170074760Abstract: An assembling apparatus assembles beads different in particle size from each other. The assembling apparatus includes a substrate and a photothermal light source. The substrate is constructed to be able to hold a sample in which the beads are dispersed. The photothermal light source irradiates the substrate or the sample with laser beams to thereby produce a temperature difference in the sample.Type: ApplicationFiled: May 8, 2015Publication date: March 16, 2017Inventors: Takuya IIDA, Shiho TOKONAMI, Ikuhiko NAKASE, Yushi NISHIMURA, Yasuyuki YAMAMOTO
-
Publication number: 20170051242Abstract: A polymer membrane for cancer cell detection having a surface provided with a mold having a three-dimensional structure complementary to a portion of a steric structure of a cancer cell to be detected; a method of producing the same; and a cancer cell detection device including the polymer membrane are provided. The polymer membrane for cancer cell detection can be obtained, for example, by a producing method including: polymerizing monomers in presence of cancer cells to be detected, to form a cancer cell-containing polymer membrane having the cancer cells incorporated therein; and removing at least part of the cancer cells incorporated in the cancer cell-containing polymer membrane.Type: ApplicationFiled: April 30, 2015Publication date: February 23, 2017Inventors: Shiho TOKONAMI, Ikuhiko NAKASE
-
Publication number: 20160123968Abstract: A detection device detects an analyte that may be contained in a specimen. The detection device includes a plurality of gold nanoparticles, an optical trapping light source, an illumination light source, an objective lens, an image pick-up device, and a computation unit. The plurality of gold nanoparticles are each modified with a probe DNA allowing the analyte to specifically adhere thereto. The optical trapping light source emits polarized light for assembling the plurality of gold nanoparticles together. The objective lens focuses and introduces the polarized light into a liquid containing a specimen and the plurality of gold nanoparticles. The image pick-up device receives light from the liquid. The computation unit detects an analyte based on a signal received from the image pick-up device.Type: ApplicationFiled: May 30, 2014Publication date: May 5, 2016Applicant: OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATIONInventors: Takuya IIDA, Shiho TOKONAMI
-
Publication number: 20160018391Abstract: The present invention is a sensor for detecting a microorganism, which is provided with a detection unit equipped with a detection electrode and a polymer layer, wherein the polymer layer is arranged on the detection electrode and is provided with a template having a three-dimensional structure complementary to a three-dimensional structure of a microorganism to be detected. The sensor detects a microorganism on the basis of the captured state of the microorganism onto the template. The polymer layer is formed by a manufacturing method including a polymerization step of polymerizing a monomer in the presence of the microorganism to be detected to form a polymer layer having the microorganism incorporated therein on the detection electrode, and a disruption step of bringing at least a part of the microorganism incorporated in the polymer layer into contact with a solution containing a lytic enzyme to disrupt the microorganism.Type: ApplicationFiled: March 10, 2014Publication date: January 21, 2016Applicants: OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION, Sharp Kabushiki KaishaInventors: Mugihei IKEMIZU, Shiho TOKONAMI, Hiroshi SHIIGI, Tsutomu NAGAOKA
-
Patent number: 9206461Abstract: The present invention provides a sensor including a detection unit having a detection electrode and a polymer layer that is disposed on the detection electrode and includes a mold having a three-dimensional structure complementary to a steric structure of a microorganism to be detected. The sensor detects the microorganism based on a state of capturing the microorganism in the mold. The polymer layer is formed by a manufacturing method including: a polymerization step of polymerizing a monomer in the presence of the microorganism to be detected, to form the polymer layer having captured the microorganism on the detection electrode; a destruction step of partially destroying the microorganism captured in the polymer layer; and a peroxidation step of peroxidizing the polymer layer to release the microorganism from the polymer layer.Type: GrantFiled: March 6, 2012Date of Patent: December 8, 2015Assignees: OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION, SHARP KABUSHIKI KAISHAInventors: Shiho Tokonami, Hiroshi Shiigi, Tsutomu Nagaoka, Mugihei Ikemizu, Mari Takahashi
-
Publication number: 20130337498Abstract: The present invention provides a sensor including a detection unit having a detection electrode and a polymer layer that is disposed on the detection electrode and includes a mold having a three-dimensional structure complementary to a steric structure of a microorganism to be detected. The sensor detects the microorganism based on a state of capturing the microorganism in the mold. The polymer layer is formed by a manufacturing method including: a polymerization step of polymerizing a monomer in the presence of the microorganism to be detected, to form the polymer layer having captured the microorganism on the detection electrode; a destruction step of partially destroying the microorganism captured in the polymer layer; and a peroxidation step of peroxidizing the polymer layer to release the microorganism from the polymer layer.Type: ApplicationFiled: March 6, 2012Publication date: December 19, 2013Applicants: SHARP KABUSHIKI KAISHA, OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATIONInventors: Shiho Tokonami, Hiroshi Shiigi, Tsutomu Nagaoka, Mugihei Ikemizu, Mari Takahashi
-
Publication number: 20130252275Abstract: Disclosed is a device and method allowing a trace amount of a target substance to be detected. A metallic nanoparticle assembly structure is formed of metallic nanoparticles assembled together and modified with a host molecule allowing the target substance to specifically adhere thereto. A metallic nanorod is modified with a host molecule allowing the target substance to specifically adhere thereto. The metallic nanorod is conjugated to the metallic nanoparticle assembly structure by the target substance. An extinction spectrum of localized surface plasmon resonance or a surface enhanced Raman scattering (SERS) spectrum induced in the metallic nanoparticle assembly structure and the metallic nanostructure is measured with a spectroscope. The target substance is detected based on that spectrum.Type: ApplicationFiled: December 8, 2011Publication date: September 26, 2013Applicant: OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATIONInventors: Shiho Tokonami, Takuya Iida, Yojiro Yamamoto, Hiroshi Shiigi, Tsutomu Nagaoka
-
Publication number: 20090257907Abstract: SmCo-based alloy nanoparticles composed mainly of a SmCo-based alloy containing Sm and Co as constituent elements, wherein the content of metal elements other than Sm and Co is 0.05-20 wt % with respect to the SmCo-based alloy.Type: ApplicationFiled: March 4, 2009Publication date: October 15, 2009Applicants: TDK Corporation, Tokyo University of Science Educational Foundation Administrative OrganizationInventors: Mamoru Satoh, Naoki Toshima, Mutsuko Kinjo, Haruki Kinjo, Shiho Tokonami