Patents by Inventor Shijie Feng

Shijie Feng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11156821
    Abstract: A high-illumination numerical aperture-based large field-of-view high-resolution microimaging device, and a method for iterative reconstruction, the device comprising an LED array (1), a stage (2), a condenser (3), a microscopic objective (5), a tube lens (6), and a camera (7), the LED array (1) being arranged on the forward focal plane of the condenser (3). Light emitted by the i-th lit LED unit (8) of the LED array (1) passes through the condenser (3) and converges to become parallel light illuminating a specimen (4) to be examined, which is placed on the stage (2); part of the diffracted light passing through the specimen (4) is collected by the microscopic objective (5), converged by the tube lens (6), and reaches the imaging plane of the camera (7), forming an intensity image recorded by the camera (1). The present device and method ensure controllable programming of the illumination direction, while also ensuring an illumination-numerical-aperture up to 1.
    Type: Grant
    Filed: February 26, 2018
    Date of Patent: October 26, 2021
    Assignee: NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Qian Chen, Chao Zuo, Jiasong Sun, Shijie Feng, Yuzhen Zhang, Guohua Gu
  • Publication number: 20210325654
    Abstract: The patent discloses a differential phase contrast (DPC) quantitative phase microscopy method based on the optimal illumination pattern design. Firstly, the optimal illumination pattern corresponding to the isotropic phase transfer function of DPC quantitative phase imaging is derived, which is determined as a semi-annular illumination pattern with the illumination numerical aperture NAill equal to the numerical aperture NAobj of the objective lens. The illumination intensity distribution varies with the cosine of the illumination angle, and it can be expressed as S(?)=cos(?). This patent effectively compensates for the frequency loss of phase transfer, not only the high-frequency responses of PTF are enhanced, but also the transfer responses of low-frequency phase information is significantly improved.
    Type: Application
    Filed: July 5, 2019
    Publication date: October 21, 2021
    Applicant: Nanjing University of Science and Technology
    Inventors: Qian CHEN, Chao ZUO, Yao FAN, Jiasong SUN, Jiaji LI, Shijie FENG, Yuzhen ZHANG
  • Patent number: 11106029
    Abstract: An annular-irradiation high-resolution quantitative phase microimaging based on light intensity transfer equation is proposed here includes designing an annular aperture for the imaging system illumination; invoking the weak object approximation by using the parameters of annular illumination aperture and bright field microscopy to calculate a weak object optical transfer function (WOTF) on the basis of a partially coherent imaging theory; and collecting three intensity images by a camera and obtaining the quantitative phase image of object by resolving the light intensity transfer equation with a deconvolution algorithm.
    Type: Grant
    Filed: February 26, 2018
    Date of Patent: August 31, 2021
    Assignee: NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Qian Chen, Chao Zuo, Jiasong Sun, Shijie Feng, Yuzhen Zhang, Guohua Gu
  • Patent number: 11029144
    Abstract: A super-rapid three-dimensional measurement method and system based on an improved Fourier transform contour technique is disclosed.
    Type: Grant
    Filed: February 26, 2018
    Date of Patent: June 8, 2021
    Assignee: NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Qian Chen, Chao Zuo, Shijie Feng, Jiasong Sun, Yuzhen Zhang, Guohua Gu
  • Publication number: 20210112187
    Abstract: A high-illumination numerical aperture-based large field-of-view high-resolution microimaging device, and a method for iterative reconstruction, the device comprising an LED array (1), a stage (2), a condenser (3), a microscopic objective (5), a tube lens (6), and a camera (7), the LED array (1) being arranged on the forward focal plane of the condenser (3). Light emitted by the i-th lit LED unit (8) of the LED array (1) passes through the condenser (3) and converges to become parallel light illuminating a specimen (4) to be examined, which is placed on the stage (2); part of the diffracted light passing through the specimen (4) is collected by the microscopic objective (5), converged by the tube lens (6), and reaches the imaging plane of the camera (7), forming an intensity image recorded by the camera (1). The present device and method ensure controllable programming of the illumination direction, while also ensuring an illumination-numerical-aperture up to 1.
    Type: Application
    Filed: February 26, 2018
    Publication date: April 15, 2021
    Applicant: NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Qian CHEN, Chao ZUO, Jiasong SUN, Shijie FENG, Yuzhen ZHANG, Guohua GU
  • Publication number: 20210102801
    Abstract: A super-rapid three-dimensional measurement method and system based on an improved Fourier transform contour technique is disclosed.
    Type: Application
    Filed: February 26, 2018
    Publication date: April 8, 2021
    Applicant: NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Qian CHEN, Chao ZUO, Shijie FENG, Jiasong SUN, Yuzhen ZHANG, Guohua GU
  • Publication number: 20210103135
    Abstract: Annular-irradiation high-resolution quantitative phase microimaging based on light intensity transfer equation is proposed here. First, an annular aperture is designed for the imaging system illumination. And then, by invoking the weak object approximation, the parameters of annular illumination aperture and bright field microscopy are used to calculate a weak object optical transfer function (WOTF) on the basis of a partially coherent imaging theory. Finally, three intensity images are collected by a camera and the quantitative phase image of object is obtained by resolving the light intensity transfer equation with a deconvolution algorithm. The present method effectively resolves the tradeoff between the cloudy low-frequency noise and high-frequency fuzziness in the light intensity transfer equation, and the spatial imaging resolution of phase reconstruction is greatly increased.
    Type: Application
    Filed: February 26, 2018
    Publication date: April 8, 2021
    Applicant: NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Qian CHEN, Chao ZUO, Jiasong SUN, Shijie FENG, Yuzhen ZHANG, Guohua GU
  • Patent number: 10911672
    Abstract: A highly efficient three-dimensional image acquisition method based on multi-mode composite encoding and epipolar constraint, respectively using a fast imaging mode or a high-precision imaging mode, wherein in the fast imaging mode, two phase maps having different frequencies are obtained by four stripe gratings, and a high-frequency absolute phase is obtained by means of the epipolar constraint and a left-right consistency check, and the three-dimensional image is obtained by means of a mapping relationship between the phase and three-dimensional coordinates; and in the high precision imaging mode, two phases having different frequencies are obtained by means of N+2 stripe gratings, a low-frequency absolute phase is obtained by the epipolar constraint, and the unwrapping of a high-frequency phase is assisted by means of the low-frequency absolute phase, so as to obtain the high-frequency absolute phase, and finally, the three-dimensional image is obtained by the mapping relationship between the phase and the
    Type: Grant
    Filed: February 26, 2018
    Date of Patent: February 2, 2021
    Assignee: NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Qian Chen, Chao Zuo, Shijie Feng, Jiasong Sun, Yuzhen Zhang, Guohua Gu
  • Publication number: 20200209604
    Abstract: The invention discloses a programmable annular LED illumination-based high efficiency quantitative phase microscopy imaging method, the proposed method comprising the following steps: the derivation of system optical transfer function in a partially coherent illumination imaging system; the derivation of phase transfer function with the weak object approximation under the illumination of tilted axially symmetric coherent point illumination source; the extension of illumination from an axially symmetric coherence point source to a discrete annular point source, and the optical transfer function can be treated as an incoherent superposition of each pair of tilted axially symmetric coherent point sources. The acquisition of raw intensity dataset; the implementation of deconvolution for quantitative phase reconstruction.
    Type: Application
    Filed: February 26, 2018
    Publication date: July 2, 2020
    Applicant: NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Qian CHEN, Chao Zuo, Jiasong SUN, Shijie FENG, Yuzhen ZHANG, Guohua GU
  • Publication number: 20200128180
    Abstract: A highly efficient three-dimensional image acquisition method based on multi-mode composite encoding and epipolar constraint, respectively using a fast imaging mode or a high-precision imaging mode, wherein in the fast imaging mode, two phase maps having different frequencies are obtained by four stripe gratings, and a high-frequency absolute phase is obtained by means of the epipolar constraint and a left-right consistency check, and the three-dimensional image is obtained by means of a mapping relationship between the phase and three-dimensional coordinates; and in the high precision imaging mode, two phases having different frequencies are obtained by means of N+2 stripe gratings, a low-frequency absolute phase is obtained by the epipolar constraint, and the unwrapping of a high-frequency phase is assisted by means of the low-frequency absolute phase, so as to obtain the high-frequency absolute phase, and finally, the three-dimensional image is obtained by the mapping relationship between the phase and the
    Type: Application
    Filed: February 26, 2018
    Publication date: April 23, 2020
    Applicant: Nanjing University of Science and Technology
    Inventors: Qian Chen, Chao Zuo, Shijie Feng, Jiasong Sun, Yuzhen Zhang, Guohua Gu