Abstract: Provided are formulations of ivosidenib including a number of polymorphs. Further provided are formulations of ivosidenib containing a number of known impurities. Still further provided are stable compositions of ivosidenib.

Abstract: The present invention relates to a highly flexible, scalable multi-blockchain, hierarchical data-sharing and data-storing system, at least comprising a third-party blockchain system, a data-sharing blockchain system, and an application-layer client, wherein the data-sharing blockchain system performs data aggregation and hierarchical storage on shared data uploaded by the third-party blockchain system through accessing the data-sharing blockchain system, so as to allow the application-layer client to require the shared data from the data-sharing blockchain system. The disclosure herein creates a single reliable data-sharing blockchain apparatus based on blockchain systems, so as to facilitate aggregation of data coming from different blockchain systems, reduce node complexity and block data redundancy when data are acquired from multiple parties, and define different sharing rules for different data contents, thereby being adaptive to scenarios where data are shared among parties.

Abstract: A method for managing transfer groups at a DMA PMM using a hardware-linked list includes (i) sequentially querying and updating the transfer status of each transfer group in the transfer group queue according to the priorities of the transfer groups, (ii) configuring the transfer group queue based on the results of the query and the priorities of the transfer groups, and (iii) triggering the DMA to transfer the transfer group queue. The method enables priority management for transfer groups used in communication between chips without the need to add hardware modules, thereby avoiding an increase in chip size and manufacturing costs due to the addition of hardware modules. Furthermore, the DMA PMM provided by the present method can be flexibly applied to various different MCUs.

Abstract: The present disclosure relates to bias evaluation methods. One example method includes obtaining a to-be-verified factor, classifying a plurality of evaluation images based on the to-be-verified factor to obtain a first target evaluation image set, where the first target evaluation image set includes at least one of a first evaluation image set including the to-be-verified factor or a second evaluation image set not including the to-be-verified factor, performing style conversion on the first target evaluation image set based on the to-be-verified factor to obtain a second target evaluation image set, inputting the first target evaluation image set and the second target evaluation image set into the to-be-evaluated model for inference, and outputting a bias evaluation result of the to-be-evaluated model based on an inference result, where style conversion is implemented by removing or adding the to-be-verified factor.

Abstract: The present invention relates to an implementation method for graphic-blockchain-orientated hybrid consensus, at least comprising: calling at least one module to generate a new data block and broadcast it; calling at least one module to check and validate the received new block based on predetermined rules; calling at least one module to generate a void block; and calling at least one module to update a committee member list. The existing graphic blockchain can only achieve probabilistic consensus, yet the present invention achieves deterministic consensus on graphic blockchain for the first time, thereby reaching consensus faster. The present invention decouples generation and consensus of blocks for the first time, so that the two parts can be designed separately in a modularized manner. The present invention provides the first totally decentralized hybrid consensus algorithm in the graphic blockchain. This is unachievable to many existing graphic blockchain such as IOTA and Obyte.

Abstract: The present invention relates to a network transmission optimization device for a graph-type blockchain, at least comprising a transaction processing module, a node managing module, and a route managing module, wherein the transaction processing module performs compression on a transaction, and transaction data obtained through the compression are transmitted among different clusters through a routing node selected by the route managing module from at least one cluster, wherein the at least one cluster is obtained through dividing plural nodes by the node managing module. The network transmission optimization method provides a transaction coding scheme to the existing graph-type blockchain systems, and improve use efficiency of network bandwidth by means of parallelized broadcast. The structured network topology of the network transmission optimization method is made to address delay among nodes, and is adaptive to dynamic joining and exit of nodes, thereby improving network transmission efficiency.

Abstract: Embodiments of the present disclosure provide a natural gas separation device, the device comprising a tank, providing with an air inlet, an exhaust port, and a liquid discharge port; a liquid separation assembly, disposed in the tank and dividing an internal space of the tank into a front separation chamber and a liquid recovery chamber, the liquid separation assembly being provided with a liquid return channel for connecting the front separation chamber and the liquid recovery chamber; and a solid separation assembly, disposed in the front separation chamber and connected to the liquid separation assembly.

Abstract: The present invention relates to a method of building a dynamic overlay network topology based on cross-chain interaction between blockchains, at least comprising: selecting at least one gateway node and at least one ordinary node from at least one cross-chain interaction node; clustering the ordinary nodes into ordinary node clusters based on a clustering algorithm; building a structured network topology and cross-chain connections between the cross-chain interaction nodes based on the gateway node; performing topology building on the ordinary node clusters based on a breadth-first spanning tree algorithm.

Abstract: The present invention relates to a network transmission optimization device for a graph-type blockchain, at least comprising a transaction processing module, a node managing module, and a route managing module, wherein the transaction processing module performs compression on a transaction, and transaction data obtained through the compression are transmitted among different clusters through a routing node selected by the route managing module from at least one cluster, wherein the at least one cluster is obtained through dividing plural nodes by the node managing module. The network transmission optimization method provides a transaction coding scheme to the existing graph-type blockchain systems, and improve use efficiency of network bandwidth by means of parallelized broadcast. The structured network topology of the network transmission optimization method is made to address delay among nodes, and is adaptive to dynamic joining and exit of nodes, thereby improving network transmission efficiency.

Abstract: The present application relates to a method for preparing a substantially and diastereomerically pure crystalline ethanol solvate of Compound IIa and its use for synthesizing Ivosidenib.

Abstract: The present invention relates to a lightweight data storage apparatus for graphic blockchains, at least comprising a common transaction construction module for a user to initiate new transactions and a network broadcast module for broadcasting the transactions, wherein the apparatus further comprises a combined-transaction constructing module and a transaction deleting module, wherein the combined-transaction constructing module serves to determine whether number of transactions initiated by an account satisfies a first predetermined condition, and if yes, execute a first lightening procedure on the transactions, and the transaction deleting module serves to execute a second lightening procedure on the transactions that have been processed by the first lightening procedure and now have validation references satisfying a second predetermined condition, after which the network broadcast module broadcasts the transactions obtained after the second lightening procedure.

Abstract: The present invention relates to an implementation method for graphic-blockchain-orientated hybrid consensus, at least comprising: calling at least one module to generate a new data block and broadcast it; calling at least one module to check and validate the received new block based on predetermined rules; calling at least one module to generate a void block; and calling at least one module to update a committee member list. The existing graphic blockchain can only achieve probabilistic consensus, yet the present invention achieves deterministic consensus on graphic blockchain for the first time, thereby reaching consensus faster. The present invention decouples generation and consensus of blocks for the first time, so that the two parts can be designed separately in a modularized manner. The present invention provides the first totally decentralized hybrid consensus algorithm in the graphic blockchain. This is unachievable to many existing graphic blockchain such as IOTA and Obyte.

Abstract: The present invention relates to a highly flexible, scalable multi-blockchain, hierarchical data-sharing and data-storing system, at least comprising a third-party blockchain system, a data-sharing blockchain system, and an application-layer client, wherein the data-sharing blockchain system performs data aggregation and hierarchical storage on shared data uploaded by the third-party blockchain system through accessing the data-sharing blockchain system, so as to allow the application-layer client to require the shared data from the data-sharing blockchain system. The disclosure herein creates a single reliable data-sharing blockchain apparatus based on blockchain systems, so as to facilitate aggregation of data coming from different blockchain systems, reduce node complexity and block data redundancy when data are acquired from multiple parties, and define different sharing rules for different data contents, thereby being adaptive to scenarios where data are shared among parties.

Abstract: The present invention relates to a method of building a dynamic overlay network topology based on cross-chain interaction between blockchains, at least comprising: selecting at least one gateway node and at least one ordinary node from at least one cross-chain interaction node; clustering the ordinary nodes into ordinary node clusters based on a clustering algorithm; building a structured network topology and cross-chain connections between the cross-chain interaction nodes based on the gateway node; performing topology building on the ordinary node clusters based on a breadth-first spanning tree algorithm.

Abstract: Provided herein are various salts, including tris(hydroxymethyl)aminomethane salts and sodium salts, as well as various crystalline forms of the compound represented by the structural formula: Also provided are pharmaceutical compositions comprising these salts and crystalline forms, methods for their manufacture, and uses thereof for treating conditions, including but not limited to conditions that would benefit from inhibition of dihydroorotate dehydrogenase (DHODH).

Abstract: The present disclosure provides a white-light block polymer, an ink composition, and a manufacturing method thereof. The white-light block polymer makes it only necessary to print one ink when using inkjet printing, thereby simplifying inkjet printing processing and meanwhile preventing a crosstalk problem of pixels having different colors of light. The present disclosure makes the ink composition suitable for inkjet printing by properly mixing the white-light block polymer, an organic solvent, a surface tension modifier, and a viscosity modifier in a suitable ratio.

Abstract: Provided are formulations of ivosidenib including a number of polymorphs. Further provided are formulations of ivosidenib containing a number of known impurities. Still further provided are stable compositions of ivosidenib.

Abstract: Provided are compounds useful for treating cancer and methods of making the compounds and intermediates described herein.

Abstract: Provided are compounds useful for treating cancer and methods of making the compounds and intermediates described herein.