Patents by Inventor Shikha Vig

Shikha Vig has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Spirocyclic anti-migraine compounds
    Patent number: 7754732
    Abstract: The present invention relates to compounds of Formula (I) as antagonists of calcitonin gene-related peptide receptors (“CGRP-receptor”), pharmaceutical compositions comprising them, methods for identifying them, methods of treatment using them and their use in therapy for treatment of neurogenic vasodilation, neurogenic inflammation, migraine and other headaches, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), and other conditions the treatment of which can be effected by the antagonism of CGRP-receptors.
    Type: Grant
    Filed: January 5, 2007
    Date of Patent: July 13, 2010
    Assignee: Bristol-Myers Squibb Company
    Inventors: Prasad V. Chaturvedula, Gene M. Dubowchik, Xiang Jun J. Jiang, John E. Macor, Graham S. Poindexter, Shikha Vig
  • SPIROCYCLIC ANTI-MIGRAINE COMPOUNDS
    Publication number: 20070149502
    Abstract: The present invention relates to compounds of Formula (I) as antagonists of calcitonin gene-related peptide receptors (“CGRP-receptor”), pharmaceutical compositions comprising them, methods for identifying them, methods of treatment using them and their use in therapy for treatment of neurogenic vasodilation, neurogenic inflammation, migraine and other headaches, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), and other conditions the treatment of which can be effected by the antagonism of CGRP-receptors.
    Type: Application
    Filed: January 5, 2007
    Publication date: June 28, 2007
    Inventors: Prasad Chaturvedula, Gene Dubowchik, Xiang Jun Jiang, John Macor, Graham Poindexter, Shikha Vig
  • Amidoheterocycles as modulators of the melanocortin-4 receptor
    Patent number: 7049323
    Abstract: Novel azetidinyl and pyrrolidinyl compounds are ligands of melanocortin-4 receptors and are useful for treating conditions responsive to the modulation of melanocortin-4 receptors such as obesity, diabetes, and sexual dysfunction.
    Type: Grant
    Filed: March 30, 2004
    Date of Patent: May 23, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Prasad V. Chaturvedula, Guanglin Luo, Shikha Vig, Graham S. Poindexter, Brett R. Beno
  • Amidoheterocycles as modulators of the melanocortin-4 receptor
    Publication number: 20040224901
    Abstract: Novel azetidinyl and pyrrolidinyl compounds are ligands of melanocortin-4 receptors and are useful for treating conditions responsive to the modulation of melanocortin-4 receptors such as obesity, diabetes, and sexual dysfunction.
    Type: Application
    Filed: March 30, 2004
    Publication date: November 11, 2004
    Inventors: Prasad V. Chaturvedula, Guanglin Luo, Shikha Vig, Graham S. Poindexter, Brett R, Beno
  • Calcitonin gene related peptide receptor antagonists
    Publication number: 20040204397
    Abstract: The present invention relates to compounds of Formula (I) 1
    Type: Application
    Filed: December 5, 2003
    Publication date: October 14, 2004
    Inventors: Prasad V. Chaturvedula, Ling Chen, Rita Civiello, Charles Mark Conway, Andrew P. Degnan, Gene M. Dubowchik, Xiaojun Han, Xiang Jun J. Jiang, George N. Karageorge, Guanglin Luo, John E. Macor, Graham Poindexter, George Tora, Shikha Vig
  • Calcitonin gene related peptide receptor antagonists
    Publication number: 20040063735
    Abstract: The present invention relates to compounds of Formula (I) 1
    Type: Application
    Filed: May 27, 2003
    Publication date: April 1, 2004
    Inventors: Prasad V. Chaturvedula, Ling Chen, Rita Civiello, Charles Mark Conway, Andrew P. Degnan, Gene M. Dubowchik, Xiaojun Han, George N. Karageorge, Guanglin Luo, John E. Macor, Graham Poindexter, Shikha Vig
  • Benzodiazepinone &bgr;-amyloid inhibitors: arylacetamidoalanyl derivatives
    Patent number: 6432944
    Abstract: There is provided a series of arylacetamidoalanyl derivatives of benzodiazepinones of Formula I wherein R1 through R7 and n are defined herein, which are inhibitors of &bgr;-amyloid peptide (&bgr;-AP) production and are useful in the treatment of Alzheimer's Disease and other conditions characterized by aberrant extract cellular deposition of amyloid.
    Type: Grant
    Filed: July 2, 2001
    Date of Patent: August 13, 2002
    Assignee: Bristol-Myers Squibb Company
    Inventors: Prasad V. Chaturvedula, Suresh Yeola, Shikha Vig
  • Benzodiazepinone beta -amyloid inhibitors: arylacetamidoalanyl derivatives
    Publication number: 20020022621
    Abstract: There is provided a series of arylacetamidoalanyl derivatives of benzodiazepinones of Formula I 1
    Type: Application
    Filed: July 2, 2001
    Publication date: February 21, 2002
    Inventors: Prasad V. Chaturvedula, Suresh Yeola, Shikha Vig